{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:21Z","timestamp":1740126861651,"version":"3.37.3"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose Detecting glaucoma damage progression is an essential component of follow-ups in glaucoma patients. It is still unclear which of the currently available and routinely used\n          parameters of glaucoma damage heralds the loss of retinal ganglion cells first. We analysed local hospital data on primary open-angle glaucoma (POAG) patients and looked for correlations\n          between the optical coherence tomography (OCT) structural, OCT angiography (OCTA), and visual field (VF) parameters.<\/jats:p><jats:p>\n          Patients and Methods Results of eye examinations of POAG patients at baseline, 6 months, and 12 months were analysed. Inclusion criteria were, apart from the diagnosis of POAG,\n          availability and quality of all modalities of examination data and no surgical intervention on the eyes during the observation period. Data on VF mean defect (MD), OCT peripapillary nerve\n          fibre layer (RNFL), OCT macular ganglion cell layer, and OCTA, peripapillary and in the macula, were parameters of interest. Correlations of structural (OCT and OCTA) on one, and functional\n          parameters (VF MD) on the other side, at baseline and as changing over time (first 6 months vs. second 6 months) were performed.<\/jats:p><jats:p>\n          Results All together, data from 78 eyes of 78 POAG patients were included in the analysis. Correlations at baseline were all highly significant (Spearman\u02bcs r-coefficients between\n          0.31 and 0.8, all p\u2009&lt;\u20090.05). None of the correlations of parameter changes over time were significant (all p\u2009&gt;\u20090.05).<\/jats:p><jats:p>\n          Conclusion Whereas a robust correlation was observed at baseline between the structural (OCT and OCTA) and functional (VF MD) parameters, none of the examination modality could\n          predict a change in the other modalities during the 1-year period. Results confirm the necessity of regularly performing both the structural and functional examinations in our glaucoma\n          patients.<\/jats:p>","DOI":"10.1055\/a-1997-9328","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T22:42:48Z","timestamp":1682462568000},"page":"472-477","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective Analysis of Prognostic Value of Optical Coherence Tomography Angiography for the Development of Glaucomatous Damage \u2013 One Year Follow-Up Retrospective\n          Observational Cohort Analysis"],"prefix":"10.1055","volume":"240","author":[{"given":"Olivia","family":"Bollinger","sequence":"additional","affiliation":[{"name":"Eye Department, University Hospital Basel Eye Clinic, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3520-2791","authenticated-orcid":false,"given":"Konstantin","family":"Gugleta","sequence":"additional","affiliation":[{"name":"Eye Department, University Hospital Basel Eye Clinic, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Schmetterer","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometrics, University Hospital Vienna, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0356-8262","authenticated-orcid":false,"given":"Pascal W.","family":"Hasler","sequence":"additional","affiliation":[{"name":"Eye Department, University Hospital Basel Eye Clinic, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline Chua Yu","family":"Min","sequence":"additional","affiliation":[{"name":"Singapore Eye Research Institute (SERI), Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damon Wong Wing","family":"Kee","sequence":"additional","affiliation":[{"name":"Singapore Eye Research Institute (SERI), Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,4,25]]},"reference":[{"key":"ref1","first-page":"844","article-title":"Global data on visual impairment in the year 2002","volume":"82","author":"S Resnikoff","year":"2004","journal-title":"Bull World Health Organ"},{"issue":"S 01","key":"ref2","first-page":"S1","article-title":"European Glaucoma Society Terminology and Guidelines for Glaucoma, 5th Edition","volume":"105","year":"2021","journal-title":"Br J Ophthalmol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ogla.2019.11.012","article-title":"Review of Longitudinal Glaucoma Progression: 5 Years after the Shaffer Lecture","volume":"3","author":"J S Schuman","year":"2020","journal-title":"Ophthalmol Glaucoma"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"e0249212","DOI":"10.1371\/journal.pone.0249212","article-title":"Characterizing and quantifying the temporal relationship between structural and functional change in glaucoma","volume":"16","author":"F I Chu","year":"2021","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1097\/IJG.0000000000001374","article-title":"Structure-function Relationship in Advanced Glaucoma After Reaching the RNFL Floor","volume":"28","author":"M S Sung","year":"2019","journal-title":"J Glaucoma"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ogla.2018.11.007","article-title":"Dynamic Range of the Peripapillary Retinal Vessel Density for Detecting Glaucomatous Visual Field Damage","volume":"2","author":"G N Kim","year":"2019","journal-title":"Ophthalmol Glaucoma"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/0039-6257(94)90041-8","article-title":"The vascular concept of glaucoma","volume":"38","author":"J Flammer","year":"1994","journal-title":"Surv Ophthalmol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e252","DOI":"10.1111\/aos.12298","article-title":"Ocular perfusion pressure in glaucoma","volume":"92","author":"V P Costa","year":"2014","journal-title":"Acta Ophthalmol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1055\/s-0034-1368222","article-title":"Analysis of risk factors for long-term glaucomatous damage development","volume":"231","author":"S Gross","year":"2014","journal-title":"Klin Monbl Augenheilkd"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1136\/bjophthalmol-2020-316222","article-title":"Peripapillary vessel parameters and mean ocular perfusion pressure in young healthy eyes: OCT angiography study","volume":"105","author":"Y I Yun","year":"2021","journal-title":"Br J Ophthalmol"},{"key":"ref11","first-page":"e377","article-title":"Vascular biomarkers from optical coherence tomography angiography and glaucoma: where do we stand in 2021?","volume":"100","author":"J D Shin","year":"2022","journal-title":"Acta Ophthalmol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/IJG.0000000000001979","article-title":"Comparison of the Structure-Function Relationship in Glaucoma Using Optical Microangiography in the Peripapillary Retinal Nerve Fiber Layer","volume":"31","author":"Y Nakatani","year":"2022","journal-title":"J Glaucoma"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"3222","DOI":"10.1038\/s41433-020-01367-z","article-title":"Comparative study of retinal nerve fibre layer thickness and retinal peripapillary capillary plexus microvascular vessel density: structure-function relationship analysis in glaucoma","volume":"35","author":"H Yilmaz","year":"2021","journal-title":"Eye (Lond)"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.21037\/atm.2020.03.187","article-title":"Optical coherence tomography angiography in glaucoma: analysis of the vessel density-visual field sensitivity relationship","volume":"8","author":"G Hollo","year":"2020","journal-title":"Ann Transl Med"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e0240111","DOI":"10.1371\/journal.pone.0240111","article-title":"Macular microvascular parameters in the ganglion cell-inner plexiform layer derived by optical coherence tomography angiography: Vascular structure-central visual function analysis","volume":"15","author":"C Hansen","year":"2020","journal-title":"PLoS One"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.4103\/ijo.IJO_2904_20","article-title":"Relationship between peripapillary vessel density and visual function based on Garway-Heath sectorization in open-angle glaucoma","volume":"69","author":"J M Kwon","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"ref17","first-page":"102671","article-title":"Optical coherence tomography angiography vessel density parameters in primary open-angle glaucoma","volume":"69","author":"O Khayrallah","year":"2021","journal-title":"Ann Med Surg (Lond)"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"e199","DOI":"10.1111\/aos.13914","article-title":"Optical coherence tomography angiography analysis of macular flow density in glaucoma","volume":"97","author":"R Kromer","year":"2019","journal-title":"Acta Ophthalmol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1080\/02713683.2019.1676912","article-title":"Quantitative Analysis of Microvasculature in Macular and Peripapillary Regions in Early Primary Open-Angle Glaucoma","volume":"45","author":"P Lu","year":"2020","journal-title":"Curr Eye Res"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1167\/iovs.62.1.22","article-title":"The Macular Choriocapillaris Flow in Glaucoma and Within-Day Fluctuations: An Optical Coherence Tomography Angiography Study","volume":"62","author":"P Milani","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/nyas.14732","article-title":"Combining vascular and nerve fiber layer thickness measurements to model glaucomatous focal visual field loss","volume":"1511","author":"M Kallab","year":"2022","journal-title":"Ann N Y Acad Sci"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2021-320621","article-title":"Relationship of macular ganglion cell complex thickness to choroidal microvasculature drop-out in primary open-angle glaucoma","author":"E Micheletti","year":"2022","journal-title":"Br J Ophthalmol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1016\/j.ophtha.2015.08.020","article-title":"Importance of Normal Aging in Estimating the Rate of Glaucomatous Neuroretina Rim ad Retinal Nerve Fiber Layer Loss","volume":"122","author":"J R Vianna","year":"2015","journal-title":"Ophthalmology"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1167\/iovs.15-18940","article-title":"The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma","volume":"57","author":"R Y Abe","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Klinische Monatsbl\u00e4tter f\u00fcr Augenheilkunde"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1997-9328.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T22:44:27Z","timestamp":1682462667000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1997-9328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":24,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2023,4,25]]},"published-print":{"date-parts":[[2023,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1997-9328","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0023-2165","1439-3999"],"issn-type":[{"type":"print","value":"0023-2165"},{"type":"electronic","value":"1439-3999"}],"subject":[],"published":{"date-parts":[[2023,4]]}}}