{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:19:26Z","timestamp":1766269166787},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Wir pr\u00e4sentieren den Fall einer Patientin mit schwerem Verlauf einer komplikativen mediastinalen Blutung nach endosonografisch gesteuerter transbronchialer Kryobiopsie (EBUS-TBKB) bei Verdacht einer fortgeschrittenen Lymphomerkrankung. Die EBUS-TBKB ist eine noch nicht routinem\u00e4\u00dfig angewandte effektive Untersuchungsmethode in der interventionellen Pneumologie zur Diagnose von Erkrankungen mit mediastinalen Lymphknotenvergr\u00f6\u00dferungen und intrathorakalen Tumoren, mit der gro\u00dfe Gewebezylinder im Mediastinum gewonnen werden k\u00f6nnen. Aufgrund der hohen diagnostischen Wertigkeit der endobronchialen ultraschallgesteuerten transbronchialen Nadelaspiration (EBUS-TBNA) zur Abkl\u00e4rung einer Lymphadenopathie sollte die Untersuchung nicht als Routineanwendung erfolgen. Indikationen f\u00fcr eine prim\u00e4re EBUS-TBKB k\u00f6nnen sich bei Verdacht auf intrathorakale maligne Lymphome oder andere seltene Tumoren, bei denen umfangreiches unfragmentiertes Gewebematerial f\u00fcr die Diagnosefindung erforderlich ist, ergeben. Eine seltene und bisher nicht in der Literatur beschriebene Komplikation ist ein H\u00e4matomediastinum, sodass vor Intervention eine sorgf\u00e4ltige Risikoabw\u00e4gung von m\u00f6glicherweise auftretenden Blutungskomplikationen erfolgen sollte und die invasivere Mediastinoskopie eine sicherere Untersuchungsmethode sein kann.<\/jats:p>","DOI":"10.1055\/a-2002-4972","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T23:45:30Z","timestamp":1675381530000},"page":"162-167","source":"Crossref","is-referenced-by-count":3,"title":["Komplikatives H\u00e4matomediastinum einer 76-j\u00e4hrigen Patientin nach Durchf\u00fchrung einer endosonografisch gesteuerten transbronchialen Kryobiopsie (EBUS-TBKB) bei Verdacht einer Lymphomerkrankung"],"prefix":"10.1055","volume":"77","author":[{"given":"Bj\u00f6rn","family":"Schwick","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pneumologie, Luisenhospital Aachen, Aachen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svetlana","family":"Kintsler","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Aachen, Aachen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Lindemann-Docter","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Aachen, Aachen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny","family":"Jonigk","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Aachen, Aachen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Miguel","family":"Sodi Luna","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pneumologie, Luisenhospital Aachen, Aachen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Thoraxchirurgie, Luisenhospital Aachen, Aachen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,2,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1183\/09031936.00028706","article-title":"Endobronchial ultrasound: new insight for the diagnosis of sarcoidosis","volume":"29","author":"M Wong","year":"2007","journal-title":"Eur Respir J"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.cllc.2017.11.010","article-title":"Feasibility of endobronchial ultrasound-guided transbronchial needle aspiration cytology specimens for next generation sequencing in non-small-cell lung cancer","volume":"19","author":"SP Stoy","year":"2018","journal-title":"Clin Lung 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