{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:23:11Z","timestamp":1790709791442,"version":"4.1.0"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Coronary artery disease (CAD) is frequently diagnosed in patients with aortic valve stenosis. Treatment options include surgical and interventional approaches. We therefore analyzed short-term outcomes of patients undergoing either coronary artery bypass grafting with simultaneous aortic valve replacement (CABG\u2009+\u2009AVR) or staged percutaneous coronary intervention and transcatheter aortic valve implantation (PCI\u2009+\u2009TAVI).<\/jats:p><jats:p>\n          Methods\u2003From all patients treated since 2017, we retrospectively identified 237 patients undergoing TAVI within 6 months after PCI and 241 patients undergoing combined CABG\u2009+\u2009AVR surgery. Propensity score matching was performed, resulting in 101 matched pairs.<\/jats:p><jats:p>\n          Results\u2003Patients in the CABG\u2009+\u2009AVR group were younger compared with patients in the PCI\u2009+\u2009TAVI group (71.9\u2009\u00b1\u20094.9 vs 81.4\u2009\u00b1\u20093.6 years; p\u2009&lt;\u20090.001). The overall mortality at 30 days before matching was higher after CABG\u2009+\u2009AVR than after PCI\u2009+\u2009TAVI (7.8 vs 2.1%; p\u2009=\u20090.012). The paired cohort was balanced for both groups regarding demographic variables and the risk profile (age: 77.2\u2009\u00b1\u20093.7 vs78.5\u2009\u00b1\u20092.7 years; p\u2009=\u20090.141) and EuroSCORE II (6.2 vs 7.6%; p\u2009=\u20090.297). At 30 days, mortality was 4.9% in the CABG\u2009+\u2009AVR group and 1.0% in the PCI\u2009+\u2009TAVI group (p\u2009=\u20090.099). Rethoracotomy was necessary in 7.9% in the CABG\u2009+\u2009AVR, while conversion to open heart surgery was necessary in 2% in the PCI\u2009+\u2009TAVI group. The need for new pacemaker was lower after CABG\u2009+\u2009AVR than after PCI\u2009+\u2009TAVI (4.1 vs 6.9%; p\u2009=\u20090.010). No paravalvular leak (PVL) was noted in the CABG\u2009+\u2009AVR group, while the incidence of moderate-to-severe PVL after PCI\u2009+\u2009TAVI was 4.9% (p\u2009=\u20090.027).<\/jats:p><jats:p>\n          Conclusion\u2003A staged interventional approach comprises a short-term survival advantage compared with combined surgery for management of CAD and aortic stenosis. However, PCI\u2009+\u2009TAVI show a significantly higher risk of atrioventricular block and PVL. Further long-term trials are warranted.<\/jats:p>","DOI":"10.1055\/a-2003-2105","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T23:40:45Z","timestamp":1671752445000},"page":"620-631","source":"Crossref","is-referenced-by-count":10,"title":["Surgical versus Interventional Treatment of Concomitant Aortic Valve Stenosis and Coronary Artery Disease"],"prefix":"10.1055","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6859-5384","authenticated-orcid":false,"given":"Ahmed","family":"Elderia","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6568-6766","authenticated-orcid":false,"given":"Stephen","family":"Gerfer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6941-7785","authenticated-orcid":false,"given":"Kaveh","family":"Eghbalzadeh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Baldus","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parwis","family":"Rahmanian","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Kuhn","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Wahlers","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,2,3]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jcin.2017.08.045","article-title":"A novel angiographic quantification of aortic regurgitation after TAVR provides an accurate estimation of regurgitation fraction derived from cardiac magnetic resonance imaging","volume":"11","author":"M Abdel-Wahab","year":"2018","journal-title":"JACC Cardiovasc 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