{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:13Z","timestamp":1740126853760,"version":"3.37.3"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Facial Plast Surg"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mandibular fractures are among the most common facial fractures resulting from trauma. The nature of the injury, involved facial structures, presence of associated injuries, the dental status of the patient, comorbid conditions, and psychosocial context all must be considered by the surgeon when planning the optimal treatment for these patients. While consensus exists for many aspects of the management of mandibular trauma, some elements remain controversial. Three such topics\u2014antibiotic therapy, treatment of subcondylar fractures, and management of the third molar\u2014remain particularly controversial, with significant heterogeneity in practice patterns and without widely accepted evidence-based guidelines to standardize care. The goals of this work are to (1) review the historical perspective underlying these controversies, (2) summarize recent evidence shaping the current debate, and (3) highlight opportunities for continued efforts to identify best practices.<\/jats:p>","DOI":"10.1055\/a-2008-2723","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T00:16:52Z","timestamp":1672964212000},"page":"214-219","source":"Crossref","is-referenced-by-count":0,"title":["Evidence-Based Medicine for Mandible Fracture Repair: Current Controversies and Future Opportunities"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6058-1404","authenticated-orcid":false,"given":"Thomas","family":"Barrett","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Chi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.joms.2015.04.032","article-title":"The epidemiology of mandibular fractures in the United States, part 1: a review of 13,142 cases from the US National Trauma Data Bank","volume":"73","author":"P N Afrooz","year":"2015","journal-title":"J Oral Maxillofac Surg"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1097\/PRS.0000000000000717","article-title":"Evidence-based medicine: mandible fractures","volume":"134","author":"B T Morrow","year":"2014","journal-title":"Plast Reconstr Surg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1055\/s-0030-1269761","article-title":"Larry H Hollier, Jr., M.D","volume":"24","author":"L Hollier","year":"2010","journal-title":"Seminars in Plastic Surgery"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/SAP.0000000000000135","article-title":"The role of postoperative antibiotics in mandible fractures: a systematic review of the literature","volume":"75","author":"S M Shridharani","year":"2015","journal-title":"Ann Plast Surg"},{"issue":"06","key":"ref5","first-page":"431","article-title":"A study of antibiotic usage in compound mandibular fractures","volume":"33","author":"R D Zallen","year":"1975","journal-title":"J Oral Surg"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.joms.2006.01.003","article-title":"The efficacy of postoperative antibiotic regimens in the open treatment of mandibular fractures: a 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