{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:34:09Z","timestamp":1780047249968,"version":"3.53.1"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose To report the prevalence of late postoperative opacification of a hydrophilic and hydrophobic acrylic intraocular lens (IOL) and to assess the risk factors in a subset of 212\n          eyes of patients referred to the University Eye Department in Basel, Switzerland.<\/jats:p><jats:p>\n          Design Retrospective case series.<\/jats:p><jats:p>\n          Methods A survey was performed at all large ophthalmological clinics in Switzerland regarding exchanged Lentis LS-502-1 lenses, and the number of affected eyes was counted. Moreover,\n          consecutive patients who were referred to a tertiary clinic between September 2015 and November 2016 with Lentis LS-502-1 opacification were investigated. Peri- and postoperative charts,\n          medical history, and topical and systemic medications were assessed.<\/jats:p><jats:p>\n          Results A total of 674 opacified Lentis LS-502-1 lenses have been reported in Switzerland, and 212 consecutive eyes of 182 patients were included in the study. All IOLs had a similar\n          pattern of opacification with a yellowish, diffuse appearance, and most of them showed a small, paracentral, roundish area that was less affected or not at all. Arterial hypertension (73%),\n          hypercholesterolemia (34%), and diabetes (21%) were the main associated systemic diseases, and statins (34%) and betablockers (34%) were the main treatments used.<\/jats:p><jats:p>\n          Conclusions The prevalence of IOL opacification was 9.9%. No associated systemic eye disease or medications could be detected, which was implicated in the opacification process. The\n          reason for opacification remains unclear, but it seems to be unrelated to the patient\u02bcs state; therefore, it is attributed to primary calcification.<\/jats:p>","DOI":"10.1055\/a-2013-1478","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T22:42:48Z","timestamp":1682462568000},"page":"440-445","source":"Crossref","is-referenced-by-count":1,"title":["674 Cases of Late Postoperative Intraocular Lens Opacification of a Hydrophilic-Hydrophobic Acryl Intraocular Lens in Switzerland and Retrospective Opacification Risk Factor\n          Assessment of 212 Cases"],"prefix":"10.1055","volume":"240","author":[{"given":"Tabea","family":"Amon","sequence":"additional","affiliation":[{"name":"Eye Clinic, University Hospital Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Goldblum","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Pallas Clinic, Olten, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Meyer","sequence":"additional","affiliation":[{"name":"Eye Clinic, University Hospital Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Maloca","sequence":"additional","affiliation":[{"name":"IOB, University Hospital Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justus","family":"Garweg","sequence":"additional","affiliation":[{"name":"Berner Augenklinik, Bern, Switzerland"},{"name":"Swiss Eye Institute AG, Rotkreuz, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Pruente","sequence":"additional","affiliation":[{"name":"Eye Clinic, University Hospital Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Sachers","sequence":"additional","affiliation":[{"name":"Augenzentrum Bahnhof Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theo","family":"Signer","sequence":"additional","affiliation":[{"name":"Vista Clinic, Binningen, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Thumann","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal W.","family":"Hasler","sequence":"additional","affiliation":[{"name":"Eye Clinic, University Hospital Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,4,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.jcrs.2007.01.015","article-title":"Causes of intraocular lens opacification or discoloration","volume":"33","author":"L Werner","year":"2007","journal-title":"J Cataract Refract 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