{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:30:46Z","timestamp":1785540646194,"version":"3.56.0"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"02","funder":[{"DOI":"10.13039\/100017237","name":"Saitama Cardiovascular and Respiratory Center","doi-asserted-by":"crossref","award":["N\/A."],"award-info":[{"award-number":["N\/A."]}],"id":[{"id":"10.13039\/100017237","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003The bacteriological features of the frontal sinus mucosa may impose significant complications in neurosurgery, when breached unintentionally. This study aimed to investigate the bacterial flora in patients undergoing frontal craniotomy for cerebrovascular substrate surgery.<\/jats:p><jats:p>\n          Design\u2003This is a single-center prospective study.<\/jats:p><jats:p>\n          Setting\u2003When mucosal laceration occurred, the patients underwent frontal sinus reconstruction with mucosa reconstruction, preserving the nasofrontal duct.<\/jats:p><jats:p>\n          Participants\u2003We enrolled eight consecutive patients who underwent bifrontal craniotomy associated with frontal sinus mucosa laceration.<\/jats:p><jats:p>\n          Main Outcome Measures\u2003A portion of the mucosa was extracted during the reconstructive procedure and was sent for microbiological analysis.<\/jats:p><jats:p>\n          Results\u2003None of the patients presented with the bacterial flora in the mucosal cultures. No patient experienced postoperative cerebrospinal fluid leakage or meningitis. One patient with a clinical history of chronic maxillary sinusitis presented with a subcutaneous abscess around the forehead at 9 months postoperatively. The patient rapidly recovered after receiving oral administration of antibiotics.<\/jats:p><jats:p>\n          Conclusions\u2003Our findings demonstrated that the frontal sinuses were maintained in an aseptic environment in all cases. The results may encourage the development and wider use of transfrontal sinus approaches.<\/jats:p>","DOI":"10.1055\/a-2015-8371","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T23:46:39Z","timestamp":1674171999000},"page":"119-122","source":"Crossref","is-referenced-by-count":1,"title":["Frontal Sinus Mucosa Bacteriological Features: Evaluation after Unintentional Opening in Neurosurgery"],"prefix":"10.1055","volume":"85","author":[{"given":"Hiroki","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saitama Cardiovascular and Respiratory Center, Itai, Kumagaya, Saitama, Japan"},{"name":"Department of Cerebrovascular Surgery, International Medical Center, Saitama Medical University, Hidaka, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetoshi","family":"Ooigawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saitama Cardiovascular and Respiratory Center, Itai, Kumagaya, Saitama, Japan"},{"name":"Department of Cerebrovascular Surgery, International Medical Center, Saitama Medical University, Hidaka, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaima","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saitama Cardiovascular and Respiratory Center, Itai, Kumagaya, Saitama, Japan"},{"name":"Department of Cerebrovascular Surgery, International Medical Center, Saitama Medical University, Hidaka, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Yanagawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saitama Cardiovascular and Respiratory Center, Itai, Kumagaya, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Lepic","sequence":"additional","affiliation":[{"name":"Department of Cerebrovascular Surgery, International Medical Center, Saitama Medical University, Hidaka, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munehiro","family":"Otsuka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saitama Cardiovascular and Respiratory Center, Itai, Kumagaya, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goji","family":"Fushihara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Saitama Cardiovascular and Respiratory Center, Itai, Kumagaya, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kurita","sequence":"additional","affiliation":[{"name":"Department of Cerebrovascular Surgery, International Medical Center, Saitama Medical University, Hidaka, Saitama, 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