{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T09:32:22Z","timestamp":1749115942324,"version":"3.37.3"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropediatrics"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In children with therapy refractory epilepsy, the functional disconnection of one hemisphere (hemispherotomy) may be considered as a treatment option. The visual field defects and hand function effects associated with the procedure have been extensively studied. However, the effect of the hemispherotomy on gait pattern has thus far only been analyzed qualitatively, and there is limited quantitative data. At the Children's Hospital, we regularly perform standardized quantitative gait analysis studies and care for children with complex epilepsies. During the standard routine of care for two children with structural therapy refractory epilepsy, gait analysis was performed prior to and after hemispherotomy. Both patients had prenatal ischemic brain lesions, had developed severe epilepsy during the first 3 years of life, and were treated with the hemispherotomy at about 7 years of age. Interestingly, one patient did not show any changes in gait pattern, while for the other patient, differences could be observed by means of three-dimensional gait analysis. However, greater deviations to controls postoperatively may also be related to day-to-day variability.<\/jats:p>","DOI":"10.1055\/a-2021-0202","type":"journal-article","created":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T00:01:06Z","timestamp":1674864066000},"page":"397-401","source":"Crossref","is-referenced-by-count":2,"title":["Gait is not Affected by Hemispherotomy\u2014Case Report from Two Children"],"prefix":"10.1055","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2864-2246","authenticated-orcid":false,"given":"Nathalie","family":"Alexander","sequence":"additional","affiliation":[{"name":"Laboratory for Motion Analysis, Department of Paediatric Orthopaedics, Children's Hospital of Eastern Switzerland, Street Gallen, Switzerland"},{"name":"Department of Orthopaedics and Traumatology, Cantonal Hospital, St. Gallen, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Cip","sequence":"additional","affiliation":[{"name":"Department of Paediatric Orthopaedics, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Lengnick-Lampadius","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip Julian","family":"Broser","sequence":"additional","affiliation":[{"name":"Medical Faculty, University of Basel, 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