{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:11:25Z","timestamp":1787163085287,"version":"build-2736575974"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Objective\u2003This study aimed to ascertain the outcomes associated with a cervical cerclage among individuals with a history of previable prelabor rupture of membranes (PROM).<\/jats:p>\n                  <jats:p>Study Design\u2003This study was a retrospective cohort study conducted at a single tertiary center between 2011 and 2021. We included individuals with a history of previable (before 24 weeks) PROM and the subsequent viable pregnancy. Women with multifetal gestation, preterm birth (PTB) or cerclage in previous gestation, or abdominal cerclage after trachelectomy were excluded. Primary outcome was PTB rate (delivery &lt;37 weeks). Recurrence of preterm PROM and adverse composite maternal and neonatal outcomes (CMO and CNO) were evaluated as secondary outcomes. CMO included any of the following: suspected chorioamnionitis, endometritis, red blood cell transfusion, uterine rupture, unplanned hysterectomy, or death. CNO included any of the following: previable PTB (&lt;24 weeks of gestation), bronchopulmonary dysplasia, grade 3 or 4 intraventricular hemorrhage, necrotizing enterocolitis, mechanical ventilation, seizures, hypoxic ischemic encephalopathy, or death.<\/jats:p>\n                  <jats:p>Results\u2003During the study period, 118 individuals had a history of previable PROM and a documented subsequent pregnancy, out of which 74 (62.7%) met inclusion criteria. Nineteen (25.7%) of eligible individuals underwent a cerclage for prior previable PROM and were compared with controls (n\u2009=\u200955, 74.3%). Women who underwent a cerclage had higher rates of PTB\u2009&lt;\u200937 weeks (63.2 vs. 10.9%, p\u2009&lt;\u20090.001; odds ratio [OR]: 14.00, 95% confidence interval [CI]: 3.97\u201349.35) and\u2009&lt;\u200934 weeks (21.1 vs. 3.6%, p\u2009=\u20090.03; OR: 7.07, 95% CI: 1.18\u201342.39) compared with those without cerclage. Furthermore, recurrent preterm PROM and previable PTB rates were higher among patients who underwent cerclage. The survival curve further indicated that individuals with cerclage delivered earlier. CMO and CNO rates were similar in those with and without cerclage.<\/jats:p>\n                  <jats:p>Conclusion\u2003Cerclage placement in individuals with prior previable PROM was associated with higher rates of recurrent preterm PROM and PTB.<\/jats:p>\n                  <jats:p>Key Points<\/jats:p>","DOI":"10.1055\/a-2028-7633","type":"journal-article","created":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T19:25:48Z","timestamp":1675711548000},"page":"e1397-e1403","source":"Crossref","is-referenced-by-count":4,"special_numbering":"S","title":["The Role of Cerclage in Subsequent Pregnancy following Previable Prelabor Rupture of Membranes"],"prefix":"10.1055","volume":"41","author":[{"given":"Rakefet","family":"Yoeli","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shali","family":"Mazaki-Tovi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"},{"name":"Department of Obstetrics and Gynecology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5077-7008","authenticated-orcid":false,"given":"Yossi","family":"Bart","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4715-566X","authenticated-orcid":false,"given":"Michal","family":"Fishel Bartal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"},{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roni","family":"Plaschkes","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diklah","family":"Sebag","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suneet P.","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baha M.","family":"Sibai","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0720-4343","authenticated-orcid":false,"given":"Raanan","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel"},{"name":"Department of Obstetrics and Gynecology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Kassif","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Sheba Medical 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Linehan","year":"2016","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/S0002-9378(99)70111-0","article-title":"The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome","volume":"181","author":"B M Mercer","year":"1999","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1067\/mob.2003.115","article-title":"Preterm premature rupture of membranes: risks of recurrent complications in the next pregnancy among a population-based sample of gravid women","volume":"188","author":"T Lee","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/0002-9378(91)90481-6","article-title":"Rate of recurrence of preterm premature rupture of membranes in consecutive pregnancies","volume":"165","author":"T Asrat","year":"1991","journal-title":"Am J Obstet Gynecol"},{"issue":"06","key":"ref10","doi-asserted-by":"crossref","first-page":"570.e1","DOI":"10.1016\/j.ajog.2009.12.010","article-title":"Recurrence of preterm premature rupture of membranes in relation to interval between pregnancies","volume":"202","author":"D Getahun","year":"2010","journal-title":"Am J Obstet Gynecol"},{"issue":"05","key":"ref11","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1097\/AOG.0000000000001682","article-title":"Pregnancy outcomes in women with a history of previable, preterm prelabor rupture of membranes","volume":"128","author":"M A Monson","year":"2016","journal-title":"Obstet Gynecol"},{"issue":"02","key":"ref12","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1055\/s-0033-1353389","article-title":"Subsequent pregnancy after preterm prelabor rupture of membranes before 27 weeks' gestation","volume":"3","author":"J L van der Heyden","year":"2013","journal-title":"AJP 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Sbarra","year":"1985","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0002-9378(86)90404-7","article-title":"Protease production by microorganisms associated with reproductive tract infection","volume":"154","author":"J A McGregor","year":"1986","journal-title":"Am J Obstet Gynecol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0002-9378(11)90686-3","article-title":"Risk factors for preterm premature rupture of fetal membranes: a multicenter case-control study","volume":"163","author":"J H Harger","year":"1990","journal-title":"Am J Obstet Gynecol"},{"issue":"05","key":"ref19","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1515\/jpm-2017-0027","article-title":"Mid-trimester preterm premature rupture of membranes (PPROM): etiology, diagnosis, classification, international recommendations of treatment options and outcome","volume":"46","author":"M 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