{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:56:41Z","timestamp":1790704601366,"version":"4.1.0"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n                  Objectives This study aimed to evaluate elastography features of deep infiltrating endometriosis (DIE), and to define whether this technique may discriminate lesions from surrounding non-endometriotic tissue.<\/jats:p><jats:p>\n                  Methods This was an exploratory observational study on women affected by DIE treated in a third-level academic hospital gynaecology outpatient facility between 2020 and 2021. Strain elastography (SE) was conducted via transvaginal probe. Tissue deformation of DIE and surrounding tissue was expressed as percentage tissue deformation or as subjective colour score (CS; from blue=stiff to red=soft, assigned numerical values from 0 to 3). Ratios of normal tissue\/DIE were compared to ratio of normal tissue\/stiffer normal tissue area.<\/jats:p><jats:p>\n                  Results Evaluations were performed on 46 DIE nodules and surrounding tissue of the uterosacral ligaments (n=21), parametrium (n=7), rectum (n=14), and recto-vaginal septum (n =4). Irrespective of location, DIE strain ratio (3.09, IQR 2.38\u20134.14 vs. 1.25, IQR 1.11\u20131.48; p&lt;0.001) and CS ratio (4.62, IQR 3.83\u20136.94 vs. 1.13, IQR 1.06\u20131.29; p&lt;0.001) was significantly higher than that of normal tissue. ROC AUC of CS ratio was higher than ROC AUC of strain ratio (99.76%, CI.95 99.26\u2013100% vs. 91.35%, CI.95 85.23\u201397.47%; p=0.007), and best ROC threshold for CS ratio was 1.82, with a sensitivity of 97.83% (CI.95 93.48\u2013100%) and a specificity of 100% (CI.95 100\u2013100%).<\/jats:p><jats:p>\n                  Conclusions Both strain and CS ratios accurately distinguish DIE nodules at various locations. Applications of elastography in improving the diagnosis DIE, in distinguishing different DIE lesions and in monitoring DIE evolution can be envisioned and are worthy of further evaluation.<\/jats:p>","DOI":"10.1055\/a-2028-8214","type":"journal-article","created":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T00:29:16Z","timestamp":1675729756000},"page":"69-76","source":"Crossref","is-referenced-by-count":10,"title":["The Benefit of Transvaginal Elastography in Detecting Deep Endometriosis: A Feasibility Study"],"prefix":"10.1055","volume":"45","author":[{"given":"Anjeza","family":"Xholli","sequence":"additional","affiliation":[{"name":"Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6429-1220","authenticated-orcid":false,"given":"Ambrogio P","family":"Londero","sequence":"additional","affiliation":[{"name":"DINOGMI, University of Genoa, 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