{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:33:48Z","timestamp":1762900428379},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Die chronische Rhinosinusitis mit Nasenpolypen (CRSwNP) ist eine multifaktorielle entz\u00fcndliche Erkrankung der Schleimh\u00e4ute von Nase und Nasennebenh\u00f6hlen. In Deutschland sind 3 verschiedene monoklonale Antik\u00f6rper f\u00fcr die Indikation \u201eZusatztherapie zu intranasalen Glukokortikosteroiden f\u00fcr die Behandlung Erwachsener mit schwerer chronischer Rhinosinusitis mit Nasenpolypen\u201c zugelassen. Um die Verordnung in der zugelassenen Indikation (In-Label) zu dokumentieren, ist neben einer Dokumentation zahlreicher medizinischer Parameter die korrekte Auswahl der ICD-10-GM-Codierung entscheidend. Hierf\u00fcr existieren in Deutschland bislang keine konsentierten Empfehlungen.<\/jats:p><jats:p>\n          Methoden\u2002Basierend auf der internationalen Literatur und bisherigen Erfahrungen werden von einem Expertengremium von AeDA, DGHNO-KHC und Deutschem CRS-Register Codierungsm\u00f6glichkeiten von CRS und CRSwNP analysiert und auf dieser Basis eine konsentierte Empfehlung f\u00fcr die ICD-10-GM-Codierung in Deutschland ausgesprochen.<\/jats:p><jats:p>\n          Ergebnis\u2002Die Internationale statistische Klassifikation der Krankheiten und verwandter Gesundheitsprobleme ICD-10-GM (International Classification of Diseases, 10. Revision, German Modification) ist die amtliche Klassifikation zur Verschl\u00fcsselung von Diagnosen in der ambulanten und station\u00e4ren Versorgung in Deutschland. Der ICD-10-GM unterscheidet nicht ad\u00e4quat zwischen heute anerkannten klinischen und immunologischen Differenzierungen der CRSsNP und der CRSwNP. Dennoch wird insbesondere bei indiziertem Einsatz von Biologika in der Therapie der schweren CRSwNP eine m\u00f6glichst exakte Verschl\u00fcsselung mit den Codes J33.8 (im Einzelfall J33.1 oder J33.9) empfohlen.<\/jats:p><jats:p>\n          Schlussfolgerungen\u2002Das Verst\u00e4ndnis \u00fcber die immunologischen Grundlagen der CRSwNP er\u00f6ffnet neue Behandlungsans\u00e4tze mit monoklonalen Antik\u00f6rpern f\u00fcr Patienten mit schwerer, unkontrollierter Erkrankung. Hier geben wir Empfehlungen f\u00fcr eine ad\u00e4quate ICD-10-GM-Codierung in Deutschland.<\/jats:p>","DOI":"10.1055\/a-2039-1831","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T23:58:05Z","timestamp":1678233485000},"page":"349-356","source":"Crossref","is-referenced-by-count":2,"title":["Positionspapier: ICD-Codierung der chronischen Rhinosinusitis mit\u00a0Nasenpolypen (CRSwNP) im ICD-10-GM als Grundlage f\u00fcr eine Therapie mit Biologika"],"prefix":"10.1055","volume":"102","author":[{"given":"S.","family":"Becker","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Universit\u00e4tsklinik T\u00fcbingen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Laudien","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Universit\u00e4tsklinikum Kiel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"F\u00f6rster-Ruhrmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Charit\u00e9-Universit\u00e4tsmedizin Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Olze","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Charit\u00e9-Universit\u00e4tsmedizin Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Rudack","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Universit\u00e4tsklinikum M\u00fcnster"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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K.","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Universit\u00e4tsklinikum Ulm"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Dazert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Ruhr-Universit\u00e4t Bochum, St.-Elisabeth-Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Deitmer","sequence":"additional","affiliation":[{"name":"Deutsche Gesellschaft f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Bonn"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Strieth","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-Nasen-Ohren-Heilkunde, Universit\u00e4tsklinikum Bonn"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Wrede","sequence":"additional","affiliation":[{"name":"Hals-, Nasen- und Ohrenarzt, Herford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Schlenter","sequence":"additional","affiliation":[{"name":"\u00c4rzteverband Deutscher Allergologen, Wiesbaden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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Deutscher Allergologen (AeDA) und der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC)","volume":"100","author":"U F\u00f6rster-Ruhrmann","year":"2021","journal-title":"Laryngo-Rhino-Otol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1055\/a-1644-4066","article-title":"Positionspapier: Empfehlungen zur Anwendung von Omalizumab bei\u00a0chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem \u2013 Empfehlungen des \u00c4rzteverbandes Deutscher Allergologen (AeDA) und der AGs Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC)","volume":"100","author":"L Klimek","year":"2021","journal-title":"Laryngo-Rhino-Otol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1055\/a-1752-8462","article-title":"Positionspapier: Empfehlungen zur Anwendung von Mepolizumab bei chronischer RhinoSinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem \u2013 Empfehlungen des \u00c4rzteverbandes Deutscher Allergologen (AeDA) und der AG\u00b4s Klinische Immunologie, Allergologie und Umweltmedizin und Rhinologie und Rhinochirurgie der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNOKHC)","volume":"101","author":"L Klimek","year":"2022","journal-title":"Laryngo-Rhino-Otol"},{"issue":"06","key":"ref28","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1055\/a-1164-9696","article-title":"Positionspapier: Empfehlungen zur Behandlung der chronischen Rhinosinusitis w\u00e4hrend der COVID-19-Pandemie im deutschen Gesundheitssystem \u2013 Empfehlungen des \u00c4rzteverbandes Deutscher Allergologen (AeDA) und der Deutschen Gesellschaft f\u00fcr HNO-Heilkunde, Kopf- und Halschirurgie (DGHNO-KHC) \u2013 Diese Empfehlungen basieren auf dem EAACI Positionspapier \u201eTreatment of chronic RhinoSinusitis with nasal polyps (CRSwNP) in the COVID-19 pandemics \u2013 An EAACI Position Paper\u201d, Allergy, 2020 und wurden auf die Situation im deutschen Gesundheitswesen angepasst","volume":"99","author":"L Klimek","year":"2020","journal-title":"Laryngo-Rhino-Otol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.jaci.2020.05.032","article-title":"Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials","volume":"146","author":"P Gevaert","year":"2020","journal-title":"The Journal of allergy and clinical immunology"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s40629-017-0048-5","article-title":"Subtyping of polyposis nasi: phenotypes, endotypes and comorbidities","volume":"27","author":"M Koennecke","year":"2018","journal-title":"Allergo journal international"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s40629-022-00220-x","article-title":"Indicating biologics for 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