{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:14Z","timestamp":1740126854943,"version":"3.37.3"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T00:00:00Z","timestamp":1677110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Patients with congenital heart disease frequently require surgical or percutaneous interventional valve replacement after initial congenital heart defect (CHD) repair. In some of these patients, simultaneous replacement of both semilunar valves is necessary, resulting in increased procedural complexity, morbidity, and mortality. In this study, we analyze the outcomes of simultaneous aortic and pulmonary valve replacements following multiple surgical interventions for CHD.<\/jats:p><jats:p>\n          Methods\u2003This was a retrospective study of 24 patients who after initial repair of CHD underwent single-stage aortic and pulmonary valve replacement at our institution between 2003 and 2021.<\/jats:p><jats:p>\n          Results\u2003The mean age of the patients was 28\u2009\u00b1\u200913 years; the mean time since the last surgery was 15\u2009\u00b1\u200911 years. Decellularized valved homografts (DVHs) were used in nine patients, and mechanical valves were implanted in seven others. In eight patients, DVHs, biological, and mechanical valves were implanted in various combinations. The mean cardiopulmonary bypass time was 303\u2009\u00b1\u2009104\u2009minutes, and aortic cross-clamp time was 152\u2009\u00b1\u200973\u2009minutes. Two patients died at 12 and 16 days postoperatively. At a maximum follow-up time of 17 years (mean 7\u2009\u00b1\u20095 years), 95% of the surviving patients were categorized as New York Heart Association heart failure class I.<\/jats:p><jats:p>\n          Conclusion\u2003Single-stage aortic and pulmonary valve replacement after initial repair of CHD remains challenging with substantial perioperative mortality (8.3%). Nevertheless, long-term survival and clinical status at the latest follow-up were excellent. The valve type had no relevant impact on the postoperative course. The selection of the valves for implantation should take into account operation-specific factors\u2014in particular reoperability\u2014as well as the patients' wishes.<\/jats:p>","DOI":"10.1055\/a-2041-3528","type":"journal-article","created":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:05:55Z","timestamp":1677197155000},"page":"358-365","source":"Crossref","is-referenced-by-count":0,"title":["Simultaneous Aortic and Pulmonary Valve Replacement in Repaired Congenital Heart Disease"],"prefix":"10.1055","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3961-8348","authenticated-orcid":false,"given":"Dmitry","family":"Bobylev","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klea","family":"Hysko","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Avsar","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomislav","family":"Cvitkovic","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Petena","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Sarikouch","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mechthild Westhoff","family":"Bleck","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Hansmann","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Pediatric Intensive Care, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Haverich","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Horke","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Niedersachsen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"492","DOI":"10.21037\/cdt-20-831","article-title":"German Heart Centre Munich-45 years of surgery in adults with congenital heart defects: from primary corrections of septal defects and coarctation to complex reoperations","volume":"11","author":"J Pabst von Ohain","year":"2021","journal-title":"Cardiovasc Diagn Ther"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"754","DOI":"10.21037\/cdt.2018.10.06","article-title":"Current spectrum, challenges and new developments in the surgical care of adults with congenital heart disease","volume":"8","author":"J H\u00f6rer","year":"2018","journal-title":"Cardiovasc Diagn Ther"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/jocs.14316","article-title":"Late management of the aortic root after repair of tetralogy of Fallot: A European multicentre study","volume":"35","author":"V L Vida","year":"2020","journal-title":"J Card Surg"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.jjcc.2021.09.007","article-title":"Characteristics of the aortic root morphology in conotruncal anomaly of the congenital heart disease","volume":"79","author":"N Ichikawa","year":"2022","journal-title":"J Cardiol"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.athoracsur.2007.07.039","article-title":"Fate of the truncal valve in truncus arteriosus","volume":"85","author":"R Henaine","year":"2008","journal-title":"Ann Thorac Surg"},{"issue":"17","key":"ref6","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1093\/eurheartj\/ehs173","article-title":"Autograft and pulmonary allograft performance in the second post-operative decade after the Ross procedure: insights from the Rotterdam Prospective Cohort Study","volume":"33","author":"M M Mokhles","year":"2012","journal-title":"Eur Heart J"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.athoracsur.2012.12.009","article-title":"Reoperative multivalve surgery in adult congenital heart disease","volume":"95","author":"K A Holst","year":"2013","journal-title":"Ann Thorac Surg"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1161\/01.CIR.103.3.393","article-title":"Structural abnormalities of great arterial walls in congenital heart disease: light and electron microscopic analyses","volume":"103","author":"K Niwa","year":"2001","journal-title":"Circulation"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0003-4975(97)01064-3","article-title":"Trends in the management of truncal valve insufficiency","volume":"65","author":"D B McElhinney","year":"1998","journal-title":"Ann Thorac Surg"},{"issue":"06","key":"ref10","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/s00246-003-0665-2","article-title":"Late aortic root dilatation in tetralogy of Fallot may be prevented by early repair in infancy","volume":"25","author":"A H Bhat","year":"2004","journal-title":"Pediatr Cardiol"},{"issue":"06","key":"ref11","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.ejcts.2004.08.025","article-title":"Prevalence and optimal management strategy for aortic regurgitation in tetralogy of Fallot","volume":"26","author":"T Ishizaka","year":"2004","journal-title":"Eur J Cardiothorac Surg"},{"issue":"02","key":"ref12","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1161\/CIRCULATIONAHA.112.129585","article-title":"Aortic root dilatation in adults with surgically repaired tetralogy of Fallot: a multicenter cross-sectional study","volume":"127","author":"F P Mongeon","year":"2013","journal-title":"Circulation"},{"issue":"08","key":"ref13","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1007\/s10554-016-0902-4","article-title":"Dilatation of the ascending aorta is associated with presence of aortic regurgitation in patients after repair of tetralogy of Fallot","volume":"32","author":"K G Ordovas","year":"2016","journal-title":"Int J Cardiovasc Imaging"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"e004748","DOI":"10.1161\/CIRCOUTCOMES.118.004748","article-title":"The Ross procedure: a systematic review, meta-analysis, and microsimulation","volume":"11","author":"J RG Etnel","year":"2018","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/ejcts\/ezaa346","article-title":"Three-step preoperative sequential planning for pulmonary valve replacement in repaired tetralogy of Fallot using computed tomography","volume":"59","author":"P E Ferraz Cavalcanti","year":"2020","journal-title":"Eur J Cardiothorac Surg"},{"issue":"08","key":"ref16","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.3390\/jcm9082493","article-title":"Surgery for adult patients with congenital heart disease: results from the European database","volume":"9","author":"V L Vida","year":"2020","journal-title":"J Clin Med"},{"issue":"06","key":"ref17","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1093\/icvts\/ivab189","article-title":"Valve-sparing aortic root replacement in adult patients with congenital heart disease","volume":"33","author":"D Bobylev","year":"2021","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"04","key":"ref18","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1093\/ejcts\/ezaa119","article-title":"Paediatric aortic valve replacement using decellularized allografts","volume":"58","author":"A Horke","year":"2020","journal-title":"Eur J Cardiothorac Surg"},{"issue":"02","key":"ref19","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/ejcts\/ezw050","article-title":"Decellularized fresh homografts for pulmonary valve replacement: a decade of clinical experience","volume":"50","author":"S Sarikouch","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"issue":"05","key":"ref20","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1016\/j.athoracsur.2013.07.116","article-title":"Semilunar valve replacement with decellularized homograft after Damus-Kaye-Stansel anastomosis and fontan procedure","volume":"97","author":"D Bobylev","year":"2014","journal-title":"Ann Thorac Surg"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.01.013","article-title":"Management of the aortic root in adult patients with conotruncal anomalies","author":"J A Dearani","year":"2009","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"issue":"03","key":"ref22","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.jtcvs.2017.04.084","article-title":"Reoperative aortic root replacement: outcome in a contemporary series","volume":"154","author":"J Esaki","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"05","key":"ref23","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1016\/j.athoracsur.2014.11.058","article-title":"Mechanical prostheses for right ventricular outflow tract reconstruction: a systematic review and meta-analysis","volume":"99","author":"B Dunne","year":"2015","journal-title":"Ann Thorac Surg"},{"issue":"02","key":"ref24","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jtcvs.2020.06.157","article-title":"Reintervention rates after bioprosthetic pulmonary valve replacement in patients younger than 30 years of age: a multicenter analysis","volume":"161","author":"C W Baird","year":"2021","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2041-3528.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T14:45:54Z","timestamp":1730817954000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2041-3528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,23]]},"references-count":24,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,7,30]]},"published-print":{"date-parts":[[2024,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2041-3528","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published-other":{"date-parts":[[2023,2,23]]},"published":{"date-parts":[[2023,2,23]]}}}