{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:22:28Z","timestamp":1788276148866,"version":"build-2803163510"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"03","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81902264, 81902265, 81930071, 82072502, U21A20352"],"award-info":[{"award-number":["81902264, 81902265, 81930071, 82072502, U21A20352"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Project Program of National Clinical Research Center for Geriatric Disorders","award":["2020LNJJ03"],"award-info":[{"award-number":["2020LNJJ03"]}]},{"DOI":"10.13039\/501100019081","name":"Science and Technology Program of Hunan Province","doi-asserted-by":"crossref","award":["2019RS2010"],"award-info":[{"award-number":["2019RS2010"]}],"id":[{"id":"10.13039\/501100019081","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Objective Synovial abnormalities are modifiable targets for hand pain and osteoarthritis. We examined the prevalence and distribution of ultrasound-detected hand synovial abnormalities in a community-derived sample of older people in China.<\/jats:p>\n                  <jats:p>Methods Within the Xiangya Osteoarthritis Study, a community-based study, we assessed synovial hypertrophy (SH), joint effusion, and Power Doppler signal (PDS) on all fingers and thumbs of both hands using standardized ultrasound examinations (score: 0\u20133). We assessed distribution patterns of SH and effusion using \u03c72-test and interrelationships of SH and effusion in different joints and hands by generalized estimating equations.<\/jats:p>\n                  <jats:p>Results Among 3,623 participants (mean age: 64.4 years; women: 58.1%), prevalence of SH, effusion and PDS were 85.5%, 87.3% and 1.5%, respectively. Prevalence of SH, effusion and PDS increased with age, was higher in the right hand than in the left hand and was more common in proximal than in distal hand joints. SH and effusion often occurred in multiple joints (P &lt; 0.001). SH in one joint was strongly associated with presence of SH in the same joint of the opposite hand (odds ratio [OR]= 6.60, 95% confidence interval [CI]: 6.19\u20137.03) followed by SH in other joints in the same row, (OR=5.70, 95%CI: 5.32\u20136.11), and then other joints in the same ray of the same hand (OR=1.49, 95%CI: 1.39\u20131.60). Similar patterns were observed for effusion.<\/jats:p>\n                  <jats:p>Conclusion Hand synovial abnormalities are common among older people, often affect multiple hand joints and present a unique pattern. These findings suggest both systemic and mechanical factors play roles in their occurrence.<\/jats:p>","DOI":"10.1055\/a-2048-8782","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T19:17:05Z","timestamp":1678216625000},"page":"277-284","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and distribution of ultrasound-detected hand synovial abnormalities in a middle-aged and older population"],"prefix":"10.1055","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5604-7989","authenticated-orcid":false,"given":"Ting","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital, Xiangya Hospital Central South University, Changsha, China"},{"name":"Department of Ultrasonography, Xiangya Hospital Central South University, Changsha, China"},{"name":"Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"},{"name":"Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuo","family":"Yang","sequence":"first","affiliation":[{"name":"Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"},{"name":"Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"},{"name":"Health Management Center, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiya","family":"Zhang","sequence":"additional","affiliation":[{"name":"Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"},{"name":"Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Doherty","sequence":"additional","affiliation":[{"name":"Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"},{"name":"Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States"},{"name":"The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China"},{"name":"Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China"},{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliya","family":"Sarmanova","sequence":"additional","affiliation":[{"name":"Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zidan","family":"Yang","sequence":"additional","affiliation":[{"name":"Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiatian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China"},{"name":"Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abasiama D.","family":"Obotiba","sequence":"additional","affiliation":[{"name":"Department of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghua","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China"},{"name":"Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China"},{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Wei","sequence":"additional","affiliation":[{"name":"Health Management Center, Xiangya Hospital Central South University, Changsha, China"},{"name":"Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China"},{"name":"National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University, Changsha, China"},{"name":"Department of Epidemiology and Health Statistics, Central South University Xiangya School of Public Health, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,5,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1136\/ard.2003.017087","article-title":"Prevalence and determinants of one month hand pain and hand related disability in the elderly (Rotterdam study)","volume":"64","author":"S Dahaghin","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1093\/rheumatology\/kem005","article-title":"The impact of musculoskeletal hand problems in older adults: findings from the North Staffordshire Osteoarthritis Project (NorStOP)","volume":"46","author":"K Dziedzic","year":"2007","journal-title":"Rheumatology 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