{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:41:15Z","timestamp":1789202475451,"version":"build-2803163510"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"S 01","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["1R01HD077592"],"award-info":[{"award-number":["1R01HD077592"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Institutes of Health (NIH)\/Office of Research on Women's Health Building Interdisciplinary Research Careers in Women\u2019s Health scholar funds to S.R.","award":["5K12HD092535"],"award-info":[{"award-number":["5K12HD092535"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to evaluate whether transient fetal growth restriction (FGR) that resolves prior to delivery confers a similar risk of neonatal morbidity as uncomplicated FGR that persists at term.<\/jats:p><jats:p>\n            Study Design\u2003This is a secondary analysis of a medical record abstraction study of singleton live-born pregnancies delivered at a tertiary care center between 2002 and 2013. Patients with fetuses that had either persistent or transient FGR and delivered at 38 weeks or later were included. Patients with abnormal umbilical artery Doppler studies were excluded. Persistent FGR was defined as estimated fetal weight (EFW) &lt;10th percentile by gestational age from diagnosis through delivery. Transient FGR was defined as EFW &lt;10th percentile on at least one ultrasound, but not on the last ultrasound prior to delivery. The primary outcome was a composite of neonatal morbidity: neonatal intensive care unit admission, Apgar's score &lt;7 at 5\u2009minutes, neonatal resuscitation, arterial cord pH &lt;7.1, respiratory distress syndrome, transient tachypnea of the newborn, hypoglycemia, sepsis, or death. Baseline characteristics and obstetric and neonatal outcomes were compared using Wilcoxon's rank-sum and Fisher's exact test. Log binomial regression was used to adjust for confounders.<\/jats:p><jats:p>\n            Results\u2003Of 777 patients studied, 686 (88%) had persistent FGR and 91 (12%) had transient FGR. Patients with transient FGR were more likely to have a higher body mass index, gestational diabetes, diagnosed with FGR earlier in pregnancy, have spontaneous labor, and deliver at later gestational ages. There was no difference in the composite neonatal outcome (relative risk\u2009=\u20091.03, 95% confidence interval [CI] 0.72, 1.47) for transient versus persistent FGR after adjusting for confounders (adjusted relative risk\u2009=\u20090.79, 95% CI 0.54, 1.17). There were no differences in cesarean delivery or delivery complications between groups.<\/jats:p><jats:p>\n            Conclusion\u2003Neonates born at term after transient FGR do not appear to have differences in composite morbidity compared with those where uncomplicated FGR persists at term.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2051-3859","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:24:45Z","timestamp":1678407885000},"page":"e1470-e1477","source":"Crossref","is-referenced-by-count":3,"special_numbering":"S","title":["Outcomes among Neonates after a Diagnosis of Persistent or Transient Fetal Growth Restriction Delivered at Term"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1465-5027","authenticated-orcid":false,"given":"Sebastian Z.","family":"Ramos","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women & Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phinnara","family":"Has","sequence":"additional","affiliation":[{"name":"Lifespan Biostatistics, Epidemiology, and Research Design (BERD), Rhode Island Hospital, Lifespan Healthcare System, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9358-8995","authenticated-orcid":false,"given":"Alexis C.","family":"Gimovsky","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women & Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8165-3457","authenticated-orcid":false,"given":"Valery A.","family":"Danilack","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research and Evaluation, Yale University School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Savitz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women & Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"},{"name":"Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam K.","family":"Lewkowitz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women & Infants Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1097\/01.AOG.0000287616.71602.d0","article-title":"Prediction and prevention of recurrent stillbirth","volume":"110","author":"U M Reddy","year":"2007","journal-title":"Obstet Gynecol"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1097\/AOG.0000000000003070","article-title":"ACOG Practice Bulletin No. 204: fetal growth restriction","volume":"133","author":"American College of Obstetricians and Gynecologists' Committee on Practice Bulletins-Obstetrics and the Society for Maternal-Fetal Medicine","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2020.05.010","article-title":"Society for Maternal-Fetal Medicine Consult Series #52: 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