{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T05:26:00Z","timestamp":1741325160203,"version":"3.38.0"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003We aimed to evaluate the impact of membranous interventricular septum (MIS) length and calcifications of the native aortic valve (AV), via preoperative multidetector computed tomography (MDCT) scan, on postoperative atrioventricular block III (AVB\/AVB III) and permanent pacemaker implantation in surgical aortic valve replacement (SAVR).<\/jats:p><jats:p>\n          Methods\u2003We retrospectively analyzed preoperative contrast-enhanced MDCT scans and procedural outcomes of patients affected by AV stenosis who underwent SAVR at our center (June 2016\u2013December 2019). The study population was divided into two groups (AVB and non-AVB), and variables were compared with a Mann\u2013Whitney's U-test or chi-square test. Data were further analyzed using point biserial correlation and logistic regression.<\/jats:p><jats:p>\n          Results\u2003A total of 155 (38% female) patients (mean age of 71.2\u2009\u00b1\u20096 years) were enrolled in our study: conventional stented bioprosthesis (N\u2009=\u200999) and sutureless prosthesis (N\u2009=\u200956) were implanted. A postoperative AVB III was observed in 11 patients (7.1%). AVB patients had significant greater calcifications in left coronary cusp (LCC) -AV (non-AVB\u2009=\u2009181.0\u2009mm3 [82.7\u2013316.9] vs. AVB\u2009=\u2009424.8\u2009mm3 [115.9\u2013563.2], p\u2009=\u20090.044), LCC left ventricular outflow tract (LVOT) (non-AVB\u2009=\u20092.1\u2009mm3 [0\u201320.1] vs. AVB\u2009=\u200926.0\u2009mm3 [0.1\u2013138.0], p\u2009=\u20090.048), right coronary cusp (RCC) -LVOT (non-AVB\u2009=\u20090\u2009mm3 [0\u20133.5] vs. AVB\u2009=\u20092.8\u2009mm3 [0\u201329.0], p\u2009=\u20090.039), and consequently in total LVOT (non-AVB\u2009=\u20092.1\u2009mm3 [0\u201320.1] vs. AVB\u2009=\u200926.0\u2009mm3 [0.1\u2013138.0], p\u2009=\u20090.02), while their MIS was significantly shorter than in non-AVB patients (non-AVB\u2009=\u200911.3\u2009mm [9.9\u201313.4] vs. AVB\u2009=\u20099.44\u2009mm [6.98\u201310.5]; p=0.014)). Partially, these group differences correlated positively (LCC -AV, r\u2009=\u20090.201, p\u2009=\u20090.012; RCC -LVOT, r\u2009=\u20090.283, p \u2264 0.001) or negatively (MIS length, r\u2009=\u2009\u22120.202, p\u2009=\u20090.008) with new-onset AVB III.<\/jats:p><jats:p>\n          Conclusion\u2003We recommend including an MDCT in preoperative diagnostic testing for all patients undergoing surgical AVR for further risk stratification.<\/jats:p>","DOI":"10.1055\/a-2052-8848","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T00:16:37Z","timestamp":1678752997000},"page":"117-125","source":"Crossref","is-referenced-by-count":0,"title":["Baseline CT-Based Risk Factors for Atrioventricular Block after Surgical AVR"],"prefix":"10.1055","volume":"73","author":[{"given":"Marie","family":"Claes","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Klinikum N\u00fcrnberg, Paracelsus Medical University, Nuremberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Pollari","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Klinikum N\u00fcrnberg, Paracelsus Medical University, Nuremberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem","family":"Mamdooh","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Klinikum N\u00fcrnberg, Paracelsus Medical University, Nuremberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodor","family":"Fischlein","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Klinikum N\u00fcrnberg, Paracelsus Medical University, Nuremberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"E385","DOI":"10.1002\/ccd.27915","article-title":"Characteristics of and current practice patterns of pacing for high-degree atrioventricular block after transcatheter aortic valve implantation in comparison to surgical aortic valve replacement","volume":"93","author":"N Misumida","year":"2019","journal-title":"Catheter Cardiovasc Interv"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.cjca.2014.10.030","article-title":"Sutureless aortic valve replacement: a Canadian multicentre study","volume":"31","author":"A Mazine","year":"2015","journal-title":"Can J Cardiol"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.athoracsur.2016.07.044","article-title":"Conduction disorders after sutureless aortic valve replacement","volume":"103","author":"I Bouhout","year":"2017","journal-title":"Ann Thorac Surg"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.athoracsur.2018.12.037","article-title":"Sutureless aortic valve and pacemaker rate: from surgical tricks to clinical outcomes","volume":"108","author":"F Vogt","year":"2019","journal-title":"Ann Thorac Surg"},{"issue":"05","key":"ref5","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1177\/2047487318756131","article-title":"Association between serum calcium, serum phosphate and aortic stenosis with implications for prevention","volume":"25","author":"D S Wald","year":"2018","journal-title":"Eur J Prev Cardiol"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1093\/eurjpc\/zwac016","article-title":"Association of serum levels of calcium phosphate and vitamin D with risk of developing aortic stenosis: the UK Biobank cohort","volume":"29","author":"C Xia","year":"2022","journal-title":"Eur J Prev Cardiol"},{"issue":"02","key":"ref7","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1161\/01.CIR.90.2.844","article-title":"Characterization of the early lesion of \u2018degenerative\u2019 valvular aortic stenosis. 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the American College of Cardiology Foundation; and the Heart Rhythm Society","volume":"53","author":"B Surawicz","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"ref22","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1093\/ehjci\/jev343","article-title":"Calcium distribution patterns of the aortic valve as a risk factor for the need of permanent pacemaker implantation after transcatheter aortic valve implantation","volume":"17","author":"B Fujita","year":"2016","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"21","key":"ref23","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1016\/j.jcin.2016.08.034","article-title":"Predictors of permanent pacemaker implantation after transcatheter aortic valve replacement with the SAPIEN 3","volume":"9","author":"V Mauri","year":"2016","journal-title":"JACC Cardiovasc Interv"},{"issue":"03","key":"ref24","first-page":"167","article-title":"Risk of conduction disturbances following different transcatheter aortic valve prostheses: the role of aortic valve calcifications","volume":"19","author":"F Pollari","year":"2022","journal-title":"J Geriatr Cardiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.jcmg.2016.11.020","article-title":"A highly predictive risk model for pacemaker implantation after TAVR","volume":"10","author":"Y Maeno","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"issue":"03","key":"ref26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.14740\/cr1011","article-title":"Aortic valve calcification as a predictor of post-transcatheter aortic valve replacement pacemaker dependence","volume":"11","author":"E Sharma","year":"2020","journal-title":"Cardiol Res"},{"issue":"19","key":"ref27","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1016\/j.jacc.2012.02.093","article-title":"Calcific aortic stenosis: a disease of the valve and the myocardium","volume":"60","author":"M R Dweck","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"02","key":"ref29","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s11748-020-01450-y","article-title":"Modified annular suturing technique for minimizing postoperative pacemaker use after surgical aortic valve replacement","volume":"69","author":"H Yanagisawa","year":"2021","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1161\/CIRCULATIONAHA.109.926873","article-title":"Correlates and causes of death in patients with severe symptomatic aortic stenosis who are not eligible to participate in a clinical trial of transcatheter aortic valve implantation","volume":"122","author":"I Ben-Dor","year":"2010","journal-title":"Circulation"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2052-8848.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T23:50:09Z","timestamp":1741305009000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2052-8848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,13]]},"references-count":29,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2025,3,6]]},"published-print":{"date-parts":[[2025,3]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2052-8848","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published-other":{"date-parts":[[2023,3,13]]},"published":{"date-parts":[[2023,3,13]]}}}