{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:22Z","timestamp":1787004862645,"version":"build-2736575974"},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T00:00:00Z","timestamp":1680912000000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP Rep"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Congenital maxillomandibular synechia is a rare malformation that is characterized by a fusion of the maxilla and mandible. The fusion is fibrous or bony and prevents mouth opening, which causes difficulties in feeding and occasionally in breathing. Although extremely rare, neonatologists must understand the disease because it can be fatal and require emergency treatment after birth. We report the case of a very-low-birth-weight (VLBW) infant with congenital maxillomandibular synechia and other malformations, including cleft palate, syndactyly, and cryptorchidism. The patient presented with extremely limited mouth opening, and endotracheal intubation seemed impossible; fortunately, the patient did not have respiratory distress syndrome. The patient underwent surgical release of the fibrous bands on days 10 and 17, and good mouth opening was achieved. The patient was able to consume breast milk orally and was discharged home at a corrected gestational age of 1 month without recurrence of difficulty in mouth opening or any sequelae. This is the first reported case of a VLBW infant with congenital maxillomandibular synechia who required more complicated management of feeding, surgical intervention, and anesthesia.<\/jats:p>","DOI":"10.1055\/a-2070-8590","type":"journal-article","created":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T18:30:15Z","timestamp":1680978615000},"page":"e35-e39","source":"Crossref","is-referenced-by-count":3,"title":["Congenital Maxillomandibular Synechia with Multiple Malformations in a Very-Low-Birth-Weight Infant: A Case Report"],"prefix":"10.1055","volume":"13","author":[{"given":"Ryosuke","family":"Uchi","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"},{"name":"Department of Neonatology, Yokohama City University Medical Center, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayu","family":"Koto","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Nakao","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miku","family":"Hosokawa","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Ukawa","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chisa","family":"Tsurisawa","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiya","family":"Hisaeda","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shusuke","family":"Amagata","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Japanese Red Cross Medical Center, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,5,19]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1177\/000348949310200305","article-title":"Congenital oral synechiae","volume":"102","author":"M G Gartlan","year":"1993","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1597\/09-090","article-title":"Congenital syngnathia: case report and review of literature","volume":"47","author":"V G Naikmasur","year":"2010","journal-title":"Cleft Palate Craniofac J"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.ijom.2019.09.013","article-title":"Congenital syngnathia: review of clinical profile and proposal of a new classification-based management protocol","volume":"49","author":"A A Olusanya","year":"2020","journal-title":"Int J Oral Maxillofac Implants"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s12663-019-01308-8","article-title":"Congenital maxillomandibular syngnathia: review of literature and proposed new classification system","volume":"20","author":"V Kumar","year":"2021","journal-title":"J Maxillofac Oral Surg"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.tripleo.2005.10.051","article-title":"Congenital fusion of the maxilla and mandible: brief case report","volume":"102","author":"M G Shams","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"06","key":"ref6","first-page":"703","article-title":"Congenital alveolar synechiae with cleft palate","volume":"64","author":"O Salahuddin","year":"2014","journal-title":"J Pak Med Assoc"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4103\/2348-2125.176007","article-title":"Intraoral synechiae with cleft palate in an older child: a case report and review of literature","volume":"3","author":"K Mevada","year":"2016","journal-title":"J Cleft Lip Palate Craniofacial Anomalies"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/ng985","article-title":"Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes","volume":"32","author":"S Kondo","year":"2002","journal-title":"Nat Genet"},{"issue":"10","key":"ref9","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1002\/ajmg.a.36133","article-title":"Search for genetic modifiers of IRF6 and genotype-phenotype correlations in Van der Woude and popliteal pterygium syndromes","volume":"161A","author":"E J Leslie","year":"2013","journal-title":"Am J Med Genet A"}],"container-title":["American Journal of Perinatology Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2070-8590.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,10]],"date-time":"2023-12-10T06:30:09Z","timestamp":1702189809000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2070-8590"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":9,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2023,5,8]]},"published-print":{"date-parts":[[2023,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2070-8590","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2157-6998","2157-7005"],"issn-type":[{"value":"2157-6998","type":"print"},{"value":"2157-7005","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,4,8]]},"published":{"date-parts":[[2023,4]]}}}