{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T10:44:23Z","timestamp":1788518663364,"version":"build-2803163510"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>\n            Background\u2002Delayed bleeding is among the most common adverse events associated with endoscopic mucosal resection (EMR) of nonampullary duodenal polyps. We evaluated the rate of delayed bleeding and complete defect closure using a novel through-the-scope (TTS) suturing system for the closure of duodenal EMR defects. <\/jats:p><jats:p>\n            Methods\u2002We reviewed the electronic medical records of patients who underwent EMR for nonampullary duodenal polyps of \u2265\u200a10\u200amm and prophylactic defect closure with TTS suturing between March 2021 and May 2022 at centers in the USA. We evaluated the rates of delayed bleeding and complete defect closure. <\/jats:p><jats:p>\n            Results\u200236 nonconsecutive patients (61\u200a% women; mean [SD] age, 65 [12] years) underwent EMR of \u2265\u200a10-mm duodenal polyps followed by attempted defect closure with TTS suturing. The mean (SD) lesion size was 29 (19) mm, defect size was 37 (25) mm; eight polyps (22\u200a%) involved &gt;\u200a50\u200a% of the lumen circumference. Complete closure was achieved in all cases (78\u200a% with TTS suturing alone), using a median of one TTS suturing kit. There were no cases of delayed bleeding and no adverse events attributed to application of the TTS suturing device. <\/jats:p><jats:p>\n            Conclusion\u2002Prophylactic closure of nonampullary duodenal EMR defects using TTS suturing resulted in a high rate of complete closure and no delayed bleeding events. <\/jats:p>","DOI":"10.1055\/a-2077-4832","type":"journal-article","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T22:39:57Z","timestamp":1684535997000},"page":"865-870","source":"Crossref","is-referenced-by-count":16,"title":["Through-the-scope suture closure of nonampullary duodenal endoscopic mucosal resection defects: a retrospective multicenter cohort study"],"prefix":"10.1055","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6804-0645","authenticated-orcid":false,"given":"Jose Antonio","family":"Almario","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda Y.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Johns Hopkins Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Cohen","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, New York University School of Medicine, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory B.","family":"Haber","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, New York University School of Medicine, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemchand","family":"Ramberan","sequence":"additional","affiliation":[{"name":"Virginia Gastroenterology Institute, Program in Endoscopic Oncology and Advanced Endoscopy, Suffolk, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0619-5235","authenticated-orcid":false,"given":"Andrew C.","family":"Storm","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic Minnesota, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Gordon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey M.","family":"Adler","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heiko","family":"Pohl","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Dartmouth Hitchcock Medical Center, Lebanon, 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bashar","family":"Qumseya","sequence":"additional","affiliation":[{"name":"Gastroenterology, Hepatology, and Nutrition, University of Florida Health, Gainesville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter V.","family":"Draganov","sequence":"additional","affiliation":[{"name":"Gastroenterology, Hepatology, and Nutrition, University of Florida Health, Gainesville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil A.","family":"Kumta","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6646-6693","authenticated-orcid":false,"given":"Andrew","family":"Canakis","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Gastroenterology and 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