{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:36:13Z","timestamp":1740137773137,"version":"3.37.3"},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"11","funder":[{"name":"Broxmeyer Fellowship in Clinical Thrombosis and Janssen Pharmaceuticals"},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"crossref","award":["R24AG064191"],"award-info":[{"award-number":["R24AG064191"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Hellenic Medical Society of New York"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>\n            Background\u2003Coronavirus disease 2019 (COVID-19) is associated with venous and arterial thromboembolism (VTE and ATE) and all-cause mortality (ACM) in hospitalized patients. High-quality data are needed on postdischarge outcomes in patients with cardiovascular disease.<\/jats:p><jats:p>\n            Objectives\u2003To analyze outcomes and identify risk factors for ATE, VTE, and ACM in a high-risk subgroup of hospitalized COVID-19 patients with baseline cardiovascular disease.<\/jats:p><jats:p>\n            Methods\u2003We investigated postdischarge rates and associated risk factors of ATE, VTE, and ACM in 608 hospitalized COVID-19 patients with coronary artery disease, carotid artery stenosis (CAS), peripheral arterial disease (PAD), or ischemic stroke.<\/jats:p><jats:p>\n            Results\u2003Through 90 days postdischarge, outcome rates were: ATE 27.3% (10.2% myocardial infarction, 10.1% ischemic stroke, 13.2% systemic embolism, 12.7% major adverse limb event); VTE 6.9% (4.1% deep vein thrombosis, 3.6% pulmonary embolism); composite of ATE, VTE, or ACM 35.2% (214\/608). Multivariate analysis showed significant association between this composite endpoint and age &gt;75 years (odds ratio [OR]: 1.90, 95% confidence interval [CI]: 1.22\u20132.94, p\u2009=\u20090.004), PAD (OR: 3.23, 95% CI: 1.80\u20135.81, p \u2264 0.0001), CAS (OR: 1.74, 95% CI: 1.11\u20132.75, p\u2009=\u20090.017), congestive heart failure (CHF) (OR: 1.84, 95% CI: 1.02\u20133.35, p\u2009=\u20090.044), previous VTE (OR: 3.08, 95% CI: 1.75\u20135.42, p\u2009&lt;\u20090.0001), and intensive care unit (ICU) admission (OR: 2.93, 95% CI: 1.81\u20134.75, p\u2009&lt;\u20090.0001).<\/jats:p><jats:p>\n            Conclusion\u2003COVID-19 inpatients with cardiovascular disease experience high rates of ATE, VTE, or ACM through 90 days postdischarge. Age &gt;75 years, PAD, CAS, CHF, previous VTE, and ICU admission are independent risk factors.<\/jats:p>","DOI":"10.1055\/a-2087-3003","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T23:15:40Z","timestamp":1683328540000},"page":"1089-1099","source":"Crossref","is-referenced-by-count":6,"title":["Risk Factors for Postdischarge Major Thromboembolism and Mortality in Hospitalized Patients with COVID-19 with Cardiovascular Comorbidities: Insights from the CORE-19 Registry"],"prefix":"10.1055","volume":"123","author":[{"given":"Dimitrios","family":"Giannis","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Vascular Surgery, University of Thessaly, Larissa, Greece"},{"name":"Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health at Lenox Hill Hospital, New York, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Goldin","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health at Lenox Hill Hospital, New York, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husneara","family":"Rahman","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United 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States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Ngu","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Medicine, Anticoagulation and Clinical Thrombosis Services, Northwell Health at Lenox Hill Hospital, New York, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Tsang","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Qiu","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shreya","family":"Sanghani","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackson","family":"Yeh","sequence":"additional","affiliation":[{"name":"Institute of Health Systems Science, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, United States"},{"name":"Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempstead, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miltiadis","family":"Matsagkas","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University of Thessaly, Larissa, Greece"},{"name":"Department of Anesthesiology, University of Thessaly, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni","family":"Arnaoutoglou","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University of Thessaly, Larissa, Greece"},{"name":"Department of Anesthesiology, University of Thessaly, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3175-461X","authenticated-orcid":false,"given":"Alex 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