{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:23Z","timestamp":1787004863853,"version":"build-2736575974"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The purpose of this study is to report the outcome of Descemet membrane endothelial keratoplasty (DMEK) in three eyes with a complex anterior segment and an artificial iris. A retrospective chart review of three cases was performed and clinically meaningful patient characteristics, clinical events, and therapeutic interventions were outlined. A literature search was performed and the clinical course of the three cases was discussed in the context of the published literature. DMEK in the presence of an artificial iris did not match the clinical results of DMEK in uncomplicated eyes. All three eyes experienced major complications, such as failure to achieve graft adherence, early graft failure, or an immune reaction. The indication for DMEK in complex anterior segments with an artificial iris should be made with the awareness of multiple possible complications and the potentially poor prognosis of the procedure.<\/jats:p>","DOI":"10.1055\/a-2089-3588","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T19:19:56Z","timestamp":1688152796000},"page":"741-743","source":"Crossref","is-referenced-by-count":1,"title":["Descemet Membrane Endothelial Keratoplasty in Eyes with an Artificial Iris"],"prefix":"10.1055","volume":"241","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8307-5267","authenticated-orcid":false,"given":"Philip","family":"Keye","sequence":"additional","affiliation":[{"name":"Eye Center, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Reinhard","sequence":"additional","affiliation":[{"name":"Eye Center, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip Christian","family":"Maier","sequence":"additional","affiliation":[{"name":"Eye Center, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,6,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1007\/s00417-017-3600-6","article-title":"Descemet membrane endothelial keratoplasty for graft failure following penetrating keratoplasty","volume":"255","author":"S Heinzelmann","year":"2017","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1055\/a-0839-2835","article-title":"[Therapeutic Options in Endothelial Decompensation Following 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