{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:28Z","timestamp":1740126808598,"version":"3.37.3"},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\nDas prim\u00e4re maligne Melanom (PMM) der Harnwege ist eine seltene Entit\u00e4t mit weniger als 50 berichteten F\u00e4llen weltweit. Im Nachfolgenden wird der Fall einer 64-j\u00e4hrigen Patientin dargestellt. Diese stellte sich akut \u00fcber die Notaufnahme unseres Hauses mit einer Makroh\u00e4maturie vor. Im Rahmen der weiterf\u00fchrenden Diagnostik konnte ein prim\u00e4res Melanom in der Harnblase und in der Urethra diagnostiziert werden. Es erfolgte die radikale Urethrozystektomie mit pelviner Lymphadenektomie beidseits mit Ileum-Conduit-Anlage. Anschlie\u00dfend leiteten wir eine adjuvante systemische Therapie mittels Checkpointinhibitoren f\u00fcr ein Jahr ein.\n    <\/jats:p>","DOI":"10.1055\/a-2090-5013","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T22:48:57Z","timestamp":1687301337000},"page":"365-368","source":"Crossref","is-referenced-by-count":0,"title":["Prim\u00e4r pigmentiertes malignes Melanom in der Harnblase therapiert mit radikaler Urethrozystektomie und adjuvanter Therapie"],"prefix":"10.1055","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0939-8858","authenticated-orcid":false,"given":"Mohamad Hatem","family":"Albarghouth","sequence":"additional","affiliation":[{"name":"Urology, Klinikum Sankt Georg gGmbH Akademisches Lehrkrankenhaus der Universit\u00e4t Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Bothmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Urologie und Andrologie, Klinikum Sankt Georg gGmbH, Akademisches Lehrkrankenhaus der Universit\u00e4t Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Hamza","sequence":"additional","affiliation":[{"name":"Urology, Klinikum Sankt Georg gGmbH Akademisches Lehrkrankenhaus der Universit\u00e4t Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,6,20]]},"reference":[{"volume-title":"Urachal carcinoma","year":"2016","author":"A Lopez-Beltran","key":"ref1"},{"volume-title":"World Health Organization classification of tumors. Pathology and genetics of tumors of the urinary system and male genital organs","year":"2004","author":"JN Eble","key":"ref2"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1055\/s-0032-1301400","article-title":"Survival in Sinonasal Melanoma: A Meta-analysis","volume":"73","author":"MR Gore","year":"2012","journal-title":"J Neurol Surg B Skull Base"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jaad.2014.03.031","article-title":"Update on primary mucosal melanoma","volume":"71","author":"JD Tacastacas","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"224","DOI":"10.4081\/aiua.2018.3.224","article-title":"Primary melanoma of the bladder: Case report and review of the literature","volume":"90","author":"F Barillaro","year":"2018","journal-title":"Arch Ital Urol Androl"}],"container-title":["Aktuelle Urologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2090-5013.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T23:28:14Z","timestamp":1692833294000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2090-5013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,20]]},"references-count":5,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2023,8,23]]},"published-print":{"date-parts":[[2023,9]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2090-5013","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0001-7868","1438-8820"],"issn-type":[{"type":"print","value":"0001-7868"},{"type":"electronic","value":"1438-8820"}],"subject":[],"published":{"date-parts":[[2023,6,20]]}}}