{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:32:54Z","timestamp":1740126774203,"version":"3.37.3"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n                  Hintergrund Die medikament\u00f6s induzierte Schlafendoskopie (MISE) ist ein etabliertes diagnostisches Verfahren zur Beurteilung des oberen Atemwegs bei Patienten mit obstruktiver Schlafapnoe (OSA). Ein anatomisch-physiologischer Mechanismus zur \u00d6ffnung der oberen Atemwege ist das velopalatinale Coupling (VC). In der MISE wird die Atemwegs\u00f6ffnung u.a. durch Unterkiefervorschub mittels modifizierten Esmarch-Handgriffs (mEH) simuliert.<\/jats:p><jats:p>\n                  Material und Methoden Es wurden retrospektiv alle nach VOTE-Schema befundeten MISE der letzten 15 Monate eingeschlossen. H\u00e4ufigkeit und Art des Kollapses auf den anatomischen Ebenen wurden erfasst. Apnoe-Hypopnoe-Index (AHI), Body-Mass-Index (BMI) und Epworth Sleepiness Scale (ESS) wurden ermittelt. Der Effekt des mEH auf die anatomischen Ebenen wurde ausgewertet.<\/jats:p><jats:p>\n                  Ergebnisse Es konnten 61 Patienten eingeschlossen werden (f=13, m=48, 54,3\u00b112,9 J, ESS 11\u00b15,5, AHI 30,2\u00b119\/h, BMI 29,7\u00b14,5kg\/m2). Zwischen AHI und BMI konnte eine signifikante Korrelation von r=0,30 (p=0,02) ermittelt werden. Auf Velumebene wurde bei 16,4% ein konzentrischer, bei 70,5% ein anterior-posteriorer (a.p.) und bei 11,5% ein lateraler Kollaps festgestellt. Bei 75,5% der Patienten wurde mittels mEH eine Aufl\u00f6sung des Kollapses beobachtet. Bei Vorliegen eines konzentrischen Kollapses zeigte sich eine \u00d6ffnung in 33,3% der F\u00e4lle im Vergleich zu 86,5% bei a.p. Kollaps (p=0,003). Ein Zungengrundkollaps wurde in 98,0% der F\u00e4lle aufgel\u00f6st.<\/jats:p><jats:p>\n                  Schlussfolgerungen Es konnte ein Zusammenhang zwischen dem Erfolg des mEH auf die Atemwegs\u00f6ffnung auf Velumebene und dem Muster des Gaumenkollapses gezeigt werden. Insbesondere bei Hypoglossusstimulation und progenierenden Therapieverfahren scheint ein funktionierendes VC relevant zu sein, sodass der Optimierung der pr\u00e4operativen Diagnostik eine besondere Bedeutung zukommt.<\/jats:p>","DOI":"10.1055\/a-2092-3792","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T20:36:47Z","timestamp":1689194207000},"page":"120-124","source":"Crossref","is-referenced-by-count":1,"title":["Velopalatinales Coupling in der medikament\u00f6s induzierten Schlafendoskopie: Analyse der Kollapsmuster"],"prefix":"10.1055","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0032-1061","authenticated-orcid":false,"given":"Toni","family":"H\u00e4nsel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Charit\u00e9 Campus Mitte und Virchow-Klinikum, Charite Universitatsmedizin Berlin, Berlin, 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