{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:32:28Z","timestamp":1791329548874,"version":"4.3.1"},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Handchir Mikrochir Plast Chir"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Der Fallbericht beschreibt die interdisziplin\u00e4re Behandlung einer\n                    komplexen Granatsplitterverletzung des rechten Femurs bei einem\n                    18-j\u00e4hrigen ukrainischen Soldaten. Die offene mehrfragment\u00e4re\n                    Defektfraktur des Femurs mit Substanzdefekt und Osteomyelitis wurde durch\n                    mehrere multiresistenten Bakterien, u.\u2009a. Acinetobacter baumanii,\n                    verkompliziert, welche durch eine mehrfache Antibiotikatherapie nicht eradiziert\n                    werden konnte. Keimfreiheit konnte erst durch mehrfaches radikales Debridement\n                    und lokale Sp\u00fcl-Vakuum-Therapie mit hypochloriger S\u00e4ure erreicht\n                    werden. Anschlie\u00dfend wurde das Femur mit einem chim\u00e4ren\n                    Double-Barrel-Fibula-Lappenplastik rekonstruiert. Dieser Bericht unterstreicht\n                    die Bedeutung multimodaler antimikrobieller Wundbehandlungen in Zeiten\n                    zunehmender Antibiotikaresistenzen, um die plastisch-rekonstruktive Therapie zu\n                    erm\u00f6glichen.<\/jats:p>","DOI":"10.1055\/a-2108-8978","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T23:20:16Z","timestamp":1696893616000},"page":"457-461","source":"Crossref","is-referenced-by-count":1,"title":["Multiresistente Keimbesiedelung bei ukrainischen Kriegsverletzten:\n                    Notwendigkeit zur multimodalen Therapie"],"prefix":"10.1055","volume":"55","author":[{"given":"Wolfram","family":"Demmer","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Hand-, Plastische und \u00c4sthetische\n                    Chirurgie, LMU Klinikum, LMU M\u00fcnchen, M\u00fcnchen,\n                    Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene Mesas","family":"Aranda","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Hand-, Plastische und \u00c4sthetische\n                    Chirurgie, LMU Klinikum, LMU M\u00fcnchen, M\u00fcnchen,\n                    Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul Severin","family":"Wiggenhauser","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Hand-, Plastische und \u00c4sthetische\n                    Chirurgie, LMU Klinikum, LMU M\u00fcnchen, M\u00fcnchen,\n                    Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Braig","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Hand-, Plastische und \u00c4sthetische\n                    Chirurgie, LMU Klinikum, LMU M\u00fcnchen, M\u00fcnchen,\n                    Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Orthop\u00e4die und Unfallchirurgie, LMU\n                    Klinikum, LMU M\u00fcnchen, M\u00fcnchen, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Giunta","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Hand-, Plastische und \u00c4sthetische\n                    Chirurgie, LMU Klinikum, LMU M\u00fcnchen, M\u00fcnchen,\n                    Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"ref2","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1097\/00006534-197509000-00001","article-title":"The anatomy of several free flap donor sites","volume":"56","author":"G I Taylor","year":"1975","journal-title":"Plast Reconstr Surg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1097\/00006534-198803000-00011","article-title":"The \u201cdouble barrel\u201d free vascularized fibular bone graft","volume":"81","author":"N F Jones","year":"1988","journal-title":"Plast Reconstr Surg"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"S110","DOI":"10.1007\/s10039-004-0910-9","article-title":"Infekt-\/Defektpseudarthrose","volume":"7","author":"V Heppert","year":"2005","journal-title":"Trauma und Berufskrankheit"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1111\/j.1742-481X.2012.01073.x","article-title":"Comparison of tissue damage, cleansing and cross-contamination potential during\n                    wound cleansing via two methods: lavage and negative pressure wound therapy with\n                    instillation","volume":"11","author":"D Allen","year":"2014","journal-title":"Int Wound J"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1097\/00006534-197505000-00002","article-title":"The free vascularized bone graft. A clinical extension of microvascular\n                    techniques","volume":"55","author":"G I Taylor","year":"1975","journal-title":"Plast Reconstr Surg"},{"key":"ref7","first-page":"e5","article-title":"Hypochlorous acid as a potential wound care agent: part I. Stabilized\n                    hypochlorous acid: a component of the inorganic armamentarium of innate\n                    immunity","volume":"6","author":"L Wang","year":"2007","journal-title":"J Burns Wounds"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1177\/1757177420963829","article-title":"Ability of chlorhexidine, octenidine, polyhexanide and chloroxylenol to inhibit\n                    metabolism of biofilm-forming clinical multidrug-resistant organisms","volume":"22","author":"F G\u00fcnther","year":"2021","journal-title":"J Infect Prev"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17071161","article-title":"Effectiveness of Hypochlorous Acid to Reduce the Biofilms on Titanium Alloy\n                    Surfaces in Vitro","volume":"17","author":"C J Chen","year":"2016","journal-title":"Int J Mol Sci"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1097\/01.Asw.0000526607.80113.66","article-title":"Disruption of Biofilms and Neutralization of Bacteria Using Hypochlorous Acid\n                    Solution: An In Vivo and In Vitro Evaluation","volume":"30","author":"A Day","year":"2017","journal-title":"Adv Skin Wound Care"}],"container-title":["Handchirurgie \u00b7 Mikrochirurgie \u00b7 Plastische Chirurgie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2108-8978.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T12:52:43Z","timestamp":1719665563000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2108-8978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,9]]},"references-count":9,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2023,12,7]]},"published-print":{"date-parts":[[2023,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2108-8978","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0722-1819","1439-3980"],"issn-type":[{"value":"0722-1819","type":"print"},{"value":"1439-3980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,9]]}}}