{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:54:11Z","timestamp":1787316851298,"version":"build-2736575974"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Aim The aim of this study is to investigate the efficacy of placental\n                    strain ratio values measured by real-time sonoelastography and maternal\n                    subcutaneous adipose tissue thickness measured by two-dimensional\n                    ultrasonography in predicting gestational diabetes mellitus in the first\n                    trimester.<\/jats:p>\n                  <jats:p>Materials and methods The population of the study consisted of the first\n                    210 consecutive singleton pregnant women who applied for routine first-trimester\n                    screening between the 11th and 14th week of gestation.B-mode subcutaneous\n                    adipose tissue thickness sonography and real-time placental strain elastography\n                    scanning were performed.All patients underwent 75\u2009g oral glucose\n                    tolerance test between the 24th and 28th week of gestation. American Diabetes\n                    Association criteria were used in the diagnosis of gestational diabetes\n                    mellitus.<\/jats:p>\n                  <jats:p>Results It was observed that body mass index (p&lt;0.001),\n                    first-trimester fasting blood sugar (p&lt;0.001), subcutaneous adipose\n                    tissue thickness (p&lt;0.001), and placental strain ratio value\n                    (p&lt;0.001) affected the development of gestational diabetes mellitus\n                    statistically. The multivariate analysis shown that subcutaneous adipose tissue\n                    thickness (odds ratio=1.271, 95% CI=1.142\u20131.416,\n                    p&lt;0.001) and placental strain ratio value (odds ratio=3.664,\n                    95% CI=1.927\u20136.969, p&lt;0.001) were the\n                    independent risk factors affecting the development of gestational diabetes\n                    mellitus.<\/jats:p>\n                  <jats:p>Conclusions The findings of this study indicated a positive correlation\n                    between 75\u2009g oral glucose tolerance test application and first trimester\n                    subcutaneous adipose tissue thickness and placental strain ratio. Using the\n                    cut-off values of&gt;11.5\u2009mm for subcutaneous adipose tissue\n                    and&gt;0.986 for placental strain ratio, the development of gestational\n                    diabetes mellitus may be predicted in the early weeks of pregnancy.<\/jats:p>","DOI":"10.1055\/a-2109-4210","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T18:42:19Z","timestamp":1692211339000},"page":"269-276","source":"Crossref","is-referenced-by-count":4,"title":["Early Prediction of Gestational Diabetes Mellitus Using Placental\n                    Strain Elastography and Subcutaneous Adipose Tissue Thickness"],"prefix":"10.1055","volume":"227","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9129-4336","authenticated-orcid":false,"given":"Mustafa","family":"\u015eeng\u00fcl","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department, Izmir Katip Celebi University,\n                    Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halime \u015een","family":"Selim","sequence":"additional","affiliation":[{"name":"Obstetric and Gynecology, Izmir Ataturk Training and Research Hospital,\n                    Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,8,16]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s40618-016-0607-5","article-title":"Gestational diabetes mellitus: an updated overview","volume":"40","author":"E Chiefari","year":"2017","journal-title":"J Endocrinol Invest"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1097\/AOG.0000000000002501","article-title":"Implementation Bulletin No. 190: Gestational Diabetes Mellitus","volume":"131","author":"ACOG","year":"2018","journal-title":"Obstet 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