{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:32:41Z","timestamp":1740126761696,"version":"3.37.3"},"reference-count":72,"publisher":"Georg Thieme Verlag KG","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Eine ein- oder beidseitige Zwerchfellparese kann verschiedene Ursachen haben, an erster Stelle stehen (intraoperative) Verletzungen des Nervus phrenicus. In bis zu 20% der F\u00e4lle l\u00e4sst sich jedoch trotz umfangreicher Abkl\u00e4rung keine Erkl\u00e4rung finden. Die neuralgische Amyotrophie (NA, syn. Parsonage-Turner-Syndrom) ist eine h\u00e4ufige, im Alltag unterdiagnostizierte, multifokale autoimmun-inflammatorische Erkrankung, die \u00fcberwiegend proximale Nervenabschnitte der oberen Extremit\u00e4ten betrifft. Klassische Symptome sind akut einsetzende, starke Schmerzen im Bereich des Schulterg\u00fcrtels mit zeitverz\u00f6gert auftretenden Paresen der Schulter- und Armmuskulatur. In mindestens 7% der F\u00e4lle ist der N. phrenicus (mit-)betroffen. Legt man die j\u00e4hrliche Inzidenz einer NA von 1:1000 zugrunde, ist die Entit\u00e4t als Ursache einer Zwerchfellfunktionsst\u00f6rung wahrscheinlich nicht so ungew\u00f6hnlich, wie bislang angenommen. Die klinische Erfahrung zeigt jedoch, dass diese Diagnose oft nicht in Betracht gezogen und die Zwerchfellparese somit f\u00e4lschlicherweise als idiopathisch klassifiziert wird. Fatal ist dies v.a. im Hinblick auf die M\u00f6glichkeit einer medikament\u00f6sen Therapie mittels Kortikosteroiden im Akutstadium einer NA sowie einer m\u00f6glicherweise zu fr\u00fchen operativen Zwerchfellraffung aufgrund des Potenzials der Erkrankung einer spontanen Heilung auch viele Monate nach Symptombeginn.<\/jats:p><jats:p>Ziel des vorliegenden Artikels ist es, das Bewusstsein f\u00fcr die Entit\u00e4t der NA als Ursache einer Zwerchfellparese zu sch\u00e4rfen und einen standardisierten Ansatz f\u00fcr die Diagnostik und Behandlung zu etablieren.<\/jats:p>","DOI":"10.1055\/a-2113-0385","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T22:50:26Z","timestamp":1693435826000},"page":"814-824","source":"Crossref","is-referenced-by-count":2,"title":["Die neuralgische Amyotrophie: eine h\u00e4ufige Ursache uni- oder bilateraler 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