{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T18:02:01Z","timestamp":1788804121033,"version":"build-2803163510"},"reference-count":82,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitamin D plays an important role in skeletal muscle function and metabolism. The\n                    aim of this review was A) to discuss the clinical evidence of vitamin D\n                    supplementation either alone or combined with other strategies in the prevention\n                    of sarcopenia in non-sarcopenic individuals and B) to critically discuss the\n                    clinical evidence on the effect of vitamin D combined with other strategies on\n                    muscle strength, mass and function in sarcopenic individuals without vitamin D\n                    deficiency. Sparse clinical data on non-sarcopenic individuals indicate that\n                    vitamin D alone has a subtle beneficial effect on knee extensor strength at\n                    doses 880\u20131600 IU\/day without improving handgrip strength or\n                    muscle mass. When co-administered with other supplements such as protein, mixed\n                    effects appear to prevent the decline of muscle mass, possibly delaying the\n                    onset of sarcopenia in non-sarcopenic individuals, at doses of 800\u20131,000\n                    IU\/day over 6\u201312 weeks. In sarcopenic individuals, vitamin D\n                    100\u20131,000 IU\/day co-supplementation with protein results in\n                    increased handgrip strength between 9.8\u201340.5%. However, there is\n                    no strong clinical evidence that vitamin D dosage correlates with changes in\n                    muscle strength or mass. Potential sources of discrepancy among studies are\n                    discussed. Future studies with appropriate experimental design are essential to\n                    dissect the net effect of vitamin D on sarcopenia.<\/jats:p>","DOI":"10.1055\/a-2116-9240","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T22:55:30Z","timestamp":1691621730000},"page":"843-856","source":"Crossref","is-referenced-by-count":13,"title":["Current Research on Vitamin D Supplementation against Sarcopenia: A\n                    Review of Clinical Trials"],"prefix":"10.1055","volume":"44","author":[{"given":"Heidi","family":"Kressel","sequence":"additional","affiliation":[{"name":"Centre for Biomedicine, Hull York Medical School, Hull, United Kingdom\n                    of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonios","family":"Matsakas","sequence":"additional","affiliation":[{"name":"Centre for Biomedicine, Hull York Medical School, Hull, United Kingdom\n                    of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,8,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: Report of the\n                    European Working Group on Sarcopenia in Older People","volume":"39","author":"A J Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afz046","article-title":"Sarcopenia: Revised European consensus on definition and diagnosis","volume":"48","author":"A J Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jamda.2013.11.025","article-title":"Sarcopenia in Asia: Consensus report of the asian working group for\n                    sarcopenia","volume":"15","author":"L K Chen","year":"2014","journal-title":"J Am Med Dir Assoc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/gerona\/glu010","article-title":"The FNIH sarcopenia project: Rationale, study description, conference\n                    recommendations, and final estimates","volume":"69","author":"S A Studenski","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jamda.2011.01.003","article-title":"Sarcopenia: An undiagnosed condition in older adults. Current consensus\n                    definition: Prevalence, etiology, and consequences. International working group\n                    on sarcopenia","volume":"12","author":"R A Fielding","year":"2011","journal-title":"J Am Med Dir Assoc"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/gerona\/glu012","article-title":"Criteria for clinically relevant weakness and low lean mass and their\n                    longitudinal association with incident mobility impairment and mortality: The\n                    foundation for the National Institutes of Health (FNIH) sarcopenia project","volume":"69","author":"R R McLean","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40200-017-0302-x","article-title":"Prevalence of sarcopenia in the world: A systematic review and meta- analysis of\n                    general population studies","volume":"16","author":"G Shafiee","year":"2017","journal-title":"J Diabetes Metab Disord"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s13539-010-0014-2","article-title":"An overview of sarcopenia: Facts and numbers on prevalence and clinical\n                    impact","volume":"1","author":"S von Haehling","year":"2010","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jbspin.2018.08.001","article-title":"Sarcopenia","volume":"86","author":"A Tournadre","year":"2019","journal-title":"Joint Bone Spine"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0749-0690(02)00002-2","article-title":"The epidemiology of falls and syncope","volume":"18","author":"L Z Rubenstein","year":"2002","journal-title":"Clin Geriatr Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/gerona\/glr035","article-title":"Prevalence and risk factors of sarcopenia among nursing home older\n                    residents","volume":"67","author":"F Landi","year":"2012","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.clnesp.2022.01.027","article-title":"Screening, diagnosis and monitoring of sarcopenia: When to use which tool?","volume":"48","author":"L Ackermans","year":"2022","journal-title":"Clin Nutr ESPEN"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11357-013-9556-5","article-title":"Diagnostic criteria for sarcopenia and physical performance","volume":"36","author":"A Y Bijlsma","year":"2014","journal-title":"Age (Dordr)"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/agm2.12168","article-title":"Advances in research on pharmacotherapy of sarcopenia","volume":"4","author":"Y Feike","year":"2021","journal-title":"Aging Med (Milton)"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"98","DOI":"10.4235\/agmr.19.0028","article-title":"Pharmacological interventions for treatment of sarcopenia: current status of\n                    drug development for sarcopenia","volume":"23","author":"J Y Kwak","year":"2019","journal-title":"Ann Geriatr Med Res"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1007\/s12603-018-1139-9","article-title":"International clinical practice guidelines for sarcopenia (icfsr): screening,\n                    diagnosis and management","volume":"22","author":"E Dent","year":"2018","journal-title":"J Nutr Health Aging"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.arr.2010.03.004","article-title":"Resistance exercise for muscular strength in older adults: a meta-analysis","volume":"9","author":"M D Peterson","year":"2010","journal-title":"Ageing Res Rev"},{"key":"ref18","first-page":"25","article-title":"Exercise as a remedy for sarcopenia","volume":"17","author":"F Landi","year":"2014","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.jocd.2015.04.011","article-title":"Exercise and Sarcopenia","volume":"18","author":"S Phu","year":"2015","journal-title":"J Clin Densitom"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5534\/wjmh.200190","article-title":"Rehabilitation nutrition and exercise therapy for sarcopenia","volume":"40","author":"S Kakehi","year":"2022","journal-title":"World J Mens Health"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.3390\/nu11102504","article-title":"Beneficial effects of leucine supplementation on criteria for sarcopenia: a\n                    systematic review","volume":"11","author":"F M Martinez-Arnau","year":"2019","journal-title":"Nutrients"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.jamda.2012.07.005","article-title":"Protein supplementation improves physical performance in frail elderly people: A\n                    randomized, double-blind, placebo-controlled trial","volume":"13","author":"M Tieland","year":"2012","journal-title":"J Am Med Dir Assoc"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"899","DOI":"10.3945\/ajcn.113.064154","article-title":"Protein-enriched diet, with the use of lean red meat, combined with progressive\n                    resistance training enhances lean tissue mass and muscle strength and reduces\n                    circulating IL-6 concentrations in elderly women: A cluster randomized\n                    controlled trial","volume":"99","author":"R M Daly","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s12603-011-0017-5","article-title":"Effects of high-intensity exercise and protein supplement on muscle mass in ADL\n                    dependent older people with and without malnutrition: A randomized controlled\n                    trial","volume":"15","author":"M Carlsson","year":"2011","journal-title":"J Nutr Health Aging"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1093\/gerona\/gls221","article-title":"Efficacy of whey protein supplementation on resistance exercise-induced changes\n                    in lean mass, muscle strength, and physical function in mobility-limited older\n                    adults","volume":"68","author":"A Chale","year":"2013","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.clnu.2014.04.007","article-title":"Protein intake and exercise for optimal muscle function with aging:\n                    Recommendations from the ESPEN Expert Group","volume":"33","author":"N E Deutz","year":"2014","journal-title":"Clin Nutr"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1743-7075-8-68","article-title":"Skeletal muscle protein metabolism in the elderly: Interventions to counteract\n                    the 'anabolic resistance' of ageing","volume":"8","author":"L Breen","year":"2011","journal-title":"Nutr Metab (Lond)"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1080\/0264041031000140581","article-title":"Dietary supplements","volume":"22","author":"R J Maughan","year":"2004","journal-title":"J Sports Sci"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.maturitas.2015.03.014","article-title":"Sarcopenia in post-menopausal women: Is there any role for vitamin D?","volume":"82","author":"P Anagnostis","year":"2015","journal-title":"Maturitas"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jamda.2010.04.014","article-title":"Nutritional recommendations for the management of sarcopenia","volume":"11","author":"J E Morley","year":"2010","journal-title":"J Am Med Dir Assoc"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"3189","DOI":"10.3390\/nu12103189","article-title":"Vitamin D and sarcopenia: potential of vitamin d supplementation in sarcopenia\n                    prevention and treatment","volume":"12","author":"R Uchitomi","year":"2020","journal-title":"Nutrients"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3390\/biomedicines9020172","article-title":"Vitamin D and Its Role in the Lipid Metabolism and the Development of\n                    Atherosclerosis","volume":"9","author":"A M Surdu","year":"2021","journal-title":"Biomedicines"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"105423","DOI":"10.1016\/j.jsbmb.2019.105423","article-title":"Effects of vitamin D on primary human skeletal muscle cell proliferation,\n                    differentiation, protein synthesis and bioenergetics","volume":"193","author":"K Romeu Montenegro","year":"2019","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1017\/S0954422419000064","article-title":"Mechanisms of vitamin D action in skeletal muscle","volume":"32","author":"K R Montenegro","year":"2019","journal-title":"Nutr Res Rev"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1074\/jbc.M115.684399","article-title":"1alpha,25-dihydroxyvitamin d3 regulates mitochondrial oxygen consumption and\n                    dynamics in human skeletal muscle cells","volume":"291","author":"Z C Ryan","year":"2016","journal-title":"J Biol Chem"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1249\/JES.0000000000000013","article-title":"The emerging biomolecular role of vitamin D in skeletal muscle","volume":"42","author":"R M Pojednic","year":"2014","journal-title":"Exerc Sport Sci Rev"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1177\/2040622310381934","article-title":"Effects of vitamin d on muscle function and performance: A review of evidence\n                    from randomized controlled trials","volume":"2","author":"L Rejnmark","year":"2011","journal-title":"Ther Adv Chronic Dis"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.jada.2008.06.432","article-title":"Calcium, vitamin D supplementation, and physical function in the Women's\n                    Health Initiative","volume":"108","author":"R L Brunner","year":"2008","journal-title":"J Am Diet Assoc"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/ageing\/14.2.76","article-title":"Do vitamin D supplements improve the physical capabilities of elderly hospital\n                    patients?","volume":"14","author":"D Corless","year":"1985","journal-title":"Age Ageing"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1210\/jc.2005-1436","article-title":"Effect of vitamin D replacement on musculoskeletal parameters in school\n                    children: A randomized controlled trial","volume":"91","author":"G El-Hajj Fuleihan","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/BF03324819","article-title":"Muscle strength and mobility in vitamin D-insufficient female geriatric\n                    patients: A randomized controlled trial on vitamin D and calcium\n                    supplementation","volume":"22","author":"H C Janssen","year":"2010","journal-title":"Aging Clin Exp Res"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1046\/j.1532-5415.2003.51561.x","article-title":"Effects of vitamin D supplementation on strength, physical function, and health\n                    perception in older, community-dwelling men","volume":"51","author":"A M Kenny","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1152\/japplphysiol.00392.2009","article-title":"Effects of resistance exercise and fortified milk on skeletal muscle mass,\n                    muscle size, and functional performance in middle-aged and older men: An 18-mo\n                    randomized controlled trial","volume":"107","author":"S Kukuljan","year":"2009","journal-title":"J Appl Physiol (1985)"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.1532-5415.2003.51101.x","article-title":"A randomized, controlled trial of quadriceps resistance exercise and vitamin D\n                    in frail older people: The Frailty Interventions Trial in Elderly Subjects\n                    (FITNESS)","volume":"51","author":"N K Latham","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"985","DOI":"10.3945\/ajcn.2009.28113","article-title":"Once-weekly dose of 8400 IU vitamin D(3) compared with placebo: Effects on\n                    neuromuscular function and tolerability in older adults with vitamin D\n                    insufficiency","volume":"91","author":"P Lips","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1161\/CIRCHEARTFAILURE.109.907899","article-title":"The effects of vitamin D supplementation on physical function and quality of\n                    life in older patients with heart failure: A randomized controlled trial","volume":"3","author":"M D Witham","year":"2010","journal-title":"Circ Heart Fail"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.maturitas.2021.01.002","article-title":"The effect of vitamin D plus protein supplementation on sarcopenia: A systematic\n                    review and meta-analysis of randomized controlled trials","volume":"145","author":"N K Gkekas","year":"2021","journal-title":"Maturitas"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s12603-010-0287-3","article-title":"Effect of vitamin D nutritional status on muscle function and strength in\n                    healthy women aged over sixty-five years","volume":"15","author":"S R Mastaglia","year":"2011","journal-title":"J Nutr Health Aging"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.clnu.2013.09.016","article-title":"A positive association of vitamin D deficiency and sarcopenia in 50 year old\n                    women, but not men","volume":"33","author":"S Park","year":"2014","journal-title":"Clin Nutr"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.3390\/nu11122861","article-title":"Vitamin D Deficiency and Sarcopenia in Older Persons","volume":"11","author":"F Remelli","year":"2019","journal-title":"Nutrients"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1038\/ejcn.2013.144","article-title":"Low vitamin D status is associated with reduced muscle mass and impaired\n                    physical performance in frail elderly people","volume":"67","author":"M Tieland","year":"2013","journal-title":"Eur J Clin Nutr"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"5766","DOI":"10.1210\/jc.2003-030604","article-title":"Low vitamin D and high parathyroid hormone levels as determinants of loss of\n                    muscle strength and muscle mass (sarcopenia): The Longitudinal Aging Study\n                    Amsterdam","volume":"88","author":"M Visser","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1055\/a-1015-3123","article-title":"Ethical Standards in Sport and Exercise Science Research: 2020 Update","volume":"40","author":"D J Harriss","year":"2019","journal-title":"Int J Sports Med"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s11657-018-0553-2","article-title":"Vitamin D supplementation and muscle strength in pre-sarcopenic elderly Lebanese\n                    people: A randomized controlled trial","volume":"14","author":"C El Hajj","year":"2018","journal-title":"Arch Osteoporos"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/ggi.13547","article-title":"Effects of branched-chain amino acids and vitamin D supplementation on physical\n                    function, muscle mass and strength, and nutritional status in sarcopenic older\n                    adults undergoing hospital-based rehabilitation: A multicenter randomized\n                    controlled trial","volume":"19","author":"I Takeuchi","year":"2019","journal-title":"Geriatr Gerontol Int"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/jbmr.181","article-title":"The effects of whole-body vibration training and vitamin D supplementation on\n                    muscle strength, muscle mass, and bone density in institutionalized elderly\n                    women: A 6-month randomized, controlled trial","volume":"26","author":"S M Verschueren","year":"2011","journal-title":"J Bone Miner Res"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1007\/s00198-015-3151-9","article-title":"Effect of vitamin D supplementation alone on muscle function in postmenopausal\n                    women: A randomized, double-blind, placebo-controlled clinical trial","volume":"26","author":"L M Cangussu","year":"2015","journal-title":"Osteoporos Int"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/GME.0000000000000525","article-title":"Effect of isolated vitamin D supplementation on the rate of falls and postural\n                    balance in postmenopausal women fallers: A randomized, double-blind,\n                    placebo-controlled trial","volume":"23","author":"L M Cangussu","year":"2016","journal-title":"Menopause"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.3945\/jn.117.252510","article-title":"Supplementing breakfast with a vitamin d and leucine-enriched whey protein\n                    medical nutrition drink enhances postprandial muscle protein synthesis and\n                    muscle mass in healthy older men","volume":"147","author":"A Chanet","year":"2017","journal-title":"J Nutr"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.3390\/nu12061816","article-title":"Leucine-enriched protein supplementation increases lean body mass in healthy\n                    korean adults aged 50 years and older: a randomized, double-blind,\n                    placebo-controlled trial","volume":"12","author":"Y Kang","year":"2020","journal-title":"Nutrients"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s12603-019-1163-4","article-title":"Effects of 12 weeks of essential amino acids (eaa)-based multi-ingredient\n                    nutritional supplementation on muscle mass, muscle strength, muscle power and\n                    fatigue in healthy elderly subjects: a randomized controlled double-blind\n                    study","volume":"23","author":"M Negro","year":"2019","journal-title":"J Nutr Health Aging"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.3945\/jn.115.228965","article-title":"Medium-chain triglycerides in combination with leucine and vitamin d increase\n                    muscle strength and function in frail elderly adults in a randomized controlled\n                    trial","volume":"146","author":"S Abe","year":"2016","journal-title":"J Nutr"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/j.jamda.2015.05.021","article-title":"Effects of a vitamin D and leucine-enriched whey protein nutritional supplement\n                    on measures of sarcopenia in older adults, the PROVIDE study: A randomized,\n                    double-blind, placebo-controlled trial","volume":"16","author":"J M Bauer","year":"2015","journal-title":"J Am Med Dir Assoc"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.clnu.2017.12.020","article-title":"A high whey protein, vitamin D and E supplement preserves muscle mass, strength,\n                    and quality of life in sarcopenic older adults: A double-blind randomized\n                    controlled trial","volume":"38","author":"Y Bo","year":"2019","journal-title":"Clin Nutr"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1139\/apnm-2020-0643","article-title":"Effects of nutrition supplementation and physical exercise on muscle mass,\n                    muscle strength and fat mass among sarcopenic elderly: A randomized controlled\n                    trial","volume":"46","author":"Z Li","year":"2021","journal-title":"Appl Physiol Nutr Metab"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jamda.2020.08.035","article-title":"A novel fortified dairy product and sarcopenia measures in sarcopenic older\n                    adults: a double-blind randomized controlled trial","volume":"22","author":"N Nasimi","year":"2021","journal-title":"J Am Med Dir Assoc"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.3390\/nu12082391","article-title":"A five-ingredient nutritional supplement and home-based resistance exercise\n                    improve lean mass and strength in free-living elderly","volume":"12","author":"M I Nilsson","year":"2020","journal-title":"Nutrients"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1002\/jcsm.12532","article-title":"Improving rehabilitation in sarcopenia: A randomized-controlled trial utilizing\n                    a muscle-targeted food for special medical purposes","volume":"11","author":"M Rondanelli","year":"2020","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"830","DOI":"10.3945\/ajcn.115.113357","article-title":"Whey protein, amino acids, and vitamin D supplementation with physical activity\n                    increases fat-free mass and strength, functionality, and quality of life and\n                    decreases inflammation in sarcopenic elderly","volume":"103","author":"M Rondanelli","year":"2016","journal-title":"Am J Clin Nutr"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.clnu.2017.01.005","article-title":"Sufficient levels of 25-hydroxyvitamin D and protein intake required to increase\n                    muscle mass in sarcopenic older adults - The PROVIDE study","volume":"37","author":"S Verlaan","year":"2018","journal-title":"Clin Nutr"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/ggi.13643","article-title":"Synergistic effect of bodyweight resistance exercise and protein supplementation\n                    on skeletal muscle in sarcopenic or dynapenic older adults","volume":"19","author":"M Yamada","year":"2019","journal-title":"Geriatr Gerontol Int"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1093\/ageing\/afy179","article-title":"Effects of exercise and nutrition supplementation in community-dwelling older\n                    Chinese people with sarcopenia: A randomized controlled trial","volume":"48","author":"L Y Zhu","year":"2019","journal-title":"Age Ageing"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/advances\/nmy065","article-title":"The impact of dairy protein intake on muscle mass, muscle strength, and physical\n                    performance in middle-aged to older adults with or without existing sarcopenia:\n                    a systematic review and meta-analysis","volume":"10","author":"N I Hanach","year":"2019","journal-title":"Adv Nutr"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/j.1753-4887.2010.00321.x","article-title":"Effect of protein intake on bone and muscle mass in the elderly","volume":"68","author":"S Genaro Pde","year":"2010","journal-title":"Nutr Rev"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1210\/jc.2014-1742","article-title":"The effects of vitamin D on skeletal muscle strength, muscle mass, and muscle\n                    power: A systematic review and meta-analysis of randomized controlled\n                    trials","volume":"99","author":"C Beaudart","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1001\/jamainternmed.2015.3874","article-title":"Treatment of vitamin D insufficiency in postmenopausal women: a randomized\n                    clinical trial","volume":"175","author":"K E Hansen","year":"2015","journal-title":"JAMA Intern Med"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1093\/ajcn\/nqz138","article-title":"Medium-chain triglycerides (8:0 and 10:0) are promising nutrients for\n                    sarcopenia: A randomized controlled trial","volume":"110","author":"S Abe","year":"2019","journal-title":"Am J Clin Nutr"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"260","DOI":"10.2174\/1874609811104030260","article-title":"Skeletal muscle protein balance and metabolism in the elderly","volume":"4","author":"C S Fry","year":"2011","journal-title":"Curr Aging Sci"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.arr.2018.07.005","article-title":"The age-related loss of skeletal muscle mass and function: Measurement and\n                    physiology of muscle fibre atrophy and muscle fibre loss in humans","volume":"47","author":"D J Wilkinson","year":"2018","journal-title":"Ageing Res Rev"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"M221","DOI":"10.1093\/gerona\/55.4.M221","article-title":"Lower extremity function and subsequent disability: Consistency across studies,\n                    predictive models, and value of gait speed alone compared with the short\n                    physical performance battery","volume":"55","author":"J M Guralnik","year":"2000","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"676","DOI":"10.3390\/nu11030676","article-title":"Nutrigenomics of Vitamin D","volume":"11","author":"C Carlberg","year":"2019","journal-title":"Nutrients"},{"key":"ref82","first-page":"69","article-title":"Nutrigenetics and nutrigenomics: Viewpoints on the current status and\n                    applications in nutrition research and practice","volume":"4","author":"M Fenech","year":"2011","journal-title":"J Nutrigenet Nutrigenomics"}],"container-title":["International Journal of Sports 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