{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:29:08Z","timestamp":1790026148880,"version":"4.0.1"},"reference-count":81,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"name":"Ministerium f\u00fcr Wirtschaft, Arbeit und Tourismus, Baden W\u00fcrttemberg","award":["35-4223.10\/20"],"award-info":[{"award-number":["35-4223.10\/20"]}]},{"name":"Ministerium f\u00fcr Wirtschaft, Arbeit und Tourismus, Baden W\u00fcrttemberg","award":["35-4223.10\/20"],"award-info":[{"award-number":["35-4223.10\/20"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Background\u2002Photon-counting detector computed tomography (PCD-CT) is a promising new technology with the potential to fundamentally change workflows in the daily routine and provide new quantitative imaging information to improve clinical decision-making and patient management.<\/jats:p>\n                  <jats:p>Method\u2002The contents of this review are based on an unrestricted literature search of PubMed and Google Scholar using the search terms \u201cphoton-counting CT\u201d, \u201cphoton-counting detector\u201d, \u201cspectral CT\u201d, \u201ccomputed tomography\u201d as well as on the authors\u2019 own experience.<\/jats:p>\n                  <jats:p>Results\u2002The fundamental difference with respect to the currently established energy-integrating CT detectors is that PCD-CT allows for the counting of every single photon at the detector level. Based on the identified literature, PCD-CT phantom measurements and initial clinical studies have demonstrated that the new technology allows for improved spatial resolution, reduced image noise, and new possibilities for advanced quantitative image postprocessing.<\/jats:p>\n                  <jats:p>Conclusion\u2002For clinical practice, the potential benefits include fewer beam hardening artifacts, a radiation dose reduction, and the use of new or combinations of contrast agents. In particular, critical patient groups such as oncological, cardiovascular, lung, and head &amp; neck as well as pediatric patient collectives benefit from the clinical advantages.<\/jats:p>\n                  <jats:p>Key Points:\u2002<\/jats:p>\n                  <jats:p>Citation Format<\/jats:p>","DOI":"10.1055\/a-2119-5802","type":"journal-article","created":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T18:51:48Z","timestamp":1696445508000},"page":"25-35","source":"Crossref","is-referenced-by-count":35,"title":["Photon-counting computed tomography \u2013 clinical application in oncological, cardiovascular, and pediatric radiology"],"prefix":"10.1055","volume":"196","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1215-9428","authenticated-orcid":false,"given":"Florian","family":"Hagen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, University Hospital T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Soschynski","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meike","family":"Weis","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Taha","family":"Hagar","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Krumm","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, University Hospital T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Ayx","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Taron","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Krauss","sequence":"additional","affiliation":[{"name":"Department 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Krozingen, University Hospital Freiburg, Faculty of medicine, 79106 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L.","family":"Schlett","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9388-0219","authenticated-orcid":false,"given":"Jakob","family":"Neubauer","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilias","family":"Tsiflikas","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, University Hospital T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian Frederik","family":"Russe","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Arnold","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Medical Center \u2013 University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0694-9375","authenticated-orcid":false,"given":"Sebastian","family":"Faby","sequence":"additional","affiliation":[{"name":"Computed Tomography, Siemens Healthcare GmbH, Forchheim, 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