{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:51:32Z","timestamp":1791301892037,"version":"4.1.0"},"reference-count":43,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Orthop Unfall"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>High tibial osteotomy (HTO) is a widespread option to avoid or delay total knee arthroplasty (TKA). The present study aimed to assess the long-term survival rate and postoperative\n        subjective knee function after isolated medial open wedge HTO in patients with symptomatic medial compartment knee osteoarthritis (OA) and varus malalignment.<\/jats:p>\n                  <jats:p>Sixty-nine patients (48.8\u00a0\u00b1\u00a06.7, 35\u201366 years; preoperative mechanical tibiofemoral angle [mTFA] \u22125.3\u00a0\u00b1\u00a03.4; \u221214.9\u20130.0\u00b0 varus) treated with medial open wedge HTO using a TomoFix plate were\n        included in this retrospective study, with a follow-up of at least 10 years (11.8\u00a0\u00b1\u00a01.0 years). The survival rate after HTO was calculated after 5 and 10 years. Subjective knee function was\n        assessed using Hospital for Special Surgery (HSS), Oxford knee, Lequesne, and Lysholm scores.<\/jats:p>\n                  <jats:p>Thirty-three patients underwent conversion to TKA, on average, 7.0\u00a0\u00b1\u00a03.4 (1.3\u201313.7) years after HTO. Five- and ten-year survival rates were 84.1 and 60.9%, respectively. Patients without\n        conversion to TKA showed a Lysholm score of 64.5 (35\u201392), Lequesne score of 7 (1\u201313), HSS score of 71 (56\u201386), and Oxford knee score of 38.5 (25\u201344) at the last follow-up (more than 10 years).\n        Significantly higher scores were registered at the last follow-up compared to the preoperative state regarding the Lysholm score (preoperative: 43.5 [12\u201395]; follow-up: 64.5 [35\u201392];\n        p\u00a0&lt;\u00a00.001). The HSS score (preoperative: 69.5 [43\u201393]; follow-up: 71 [56\u201386]; p\u00a0=\u00a00.6941) showed no statistically significant change during the 10-year follow-up period. The Lequesne score\n        was significantly lower than the preoperative score (preoperative: 11.5 [0.5\u201322]; follow-up: 7 [1\u201313]; p\u00a0&lt;\u00a00.001), indicating a lower handicap.<\/jats:p>\n                  <jats:p>The majority of patients with a valgus medial compartmental knee OA treated with HTO with fixation using the TomoFix plate can expect no conversion to TKA for more than 10 years.\n        Furthermore, patients without conversion to TKA after 10 years still had a significantly higher subjective knee function than preoperatively. Further research is needed to identify risk\n        factors for conversion to TKA. This helps to guide surgeons in selecting patients who will benefit most from HTO.<\/jats:p>","DOI":"10.1055\/a-2120-0993","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T18:52:07Z","timestamp":1693421527000},"page":"465-473","source":"Crossref","is-referenced-by-count":9,"title":["Long-term Outcomes after Medial Open Wedge High Tibial Osteotomy \u2013 A Retrospective Study of 69 Patients"],"prefix":"10.1055","volume":"162","author":[{"given":"Steffen","family":"Schr\u00f6ter","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Unfall- und Wiederherstellungschirurgie, Diakonie Klinikum GmbH Jung-Stilling, Siegen, Germany"},{"name":"Mitglied Osteotomie Komitee der Deutschen Kniegesellschaft,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Klink","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Unfall- und Wiederherstellungschirurgie, BG Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Ihle","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Unfall- und Wiederherstellungschirurgie, BG Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boyko Guergov","family":"Gueorguiev","sequence":"additional","affiliation":[{"name":"Biomedical Services, AO Research Institute Davos, Davos, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Herbst","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Unfall- und Wiederherstellungschirurgie, BG Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Maiotti","sequence":"additional","affiliation":[{"name":"Orthopedics, Shoulder Unit Villa Stuart Clinic (Rome), Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Histing","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Unfall- und Wiederherstellungschirurgie, BG Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7044-4182","authenticated-orcid":false,"given":"Marc-Daniel","family":"Ahrend","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Unfall- und Wiederherstellungschirurgie, BG Unfallklinik T\u00fcbingen, T\u00fcbingen, Germany"},{"name":"Mitglied Osteotomie Komitee der Deutschen Kniegesellschaft,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,8,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1016\/j.arthro.2007.05.018","article-title":"The effects of valgus medial opening wedge high tibial osteotomy on articular cartilage 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Traumatol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s13018-017-0547-6","article-title":"Long-term results and comparison of the three different high tibial osteotomy and fixation techniques in medial compartment arthrosis","volume":"12","author":"G Polat","year":"2017","journal-title":"J Orthop Surg Res"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1186\/s12891-016-1076-x","article-title":"Health-related quality of life and clinical outcomes following medial open wedge high tibial osteotomy: a prospective study","volume":"17","author":"C Ihle","year":"2016","journal-title":"BMC Musculoskelet Disord"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1007\/s00167-015-3938-4","article-title":"Health-related quality of life after open-wedge high tibial osteotomy","volume":"25","author":"T Saier","year":"2017","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"S 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A retrospective evaluation of five hundred and thirty three\n          patients","volume":"38","author":"S Floerkemeier","year":"2014","journal-title":"Int Orthop"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1177\/0363546513516577","article-title":"Medial opening wedge high tibial osteotomy for medial compartment overload\/arthritis in the varus knee: prognostic factors","volume":"42","author":"DE Bonasia","year":"2014","journal-title":"Am J Sports Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.joca.2005.08.013","article-title":"Factors that influence high tibial osteotomy results in patients with medial gonarthritis: a score to predict the results","volume":"14","author":"G Spahn","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s004020050018","article-title":"High tibial osteotomy: factors influencing the duration of satisfactory function","volume":"119","author":"EM Giagounidis","year":"1999","journal-title":"Arch Orthop Trauma Surg"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1007\/s00167-022-06909-4","article-title":"Work intensity and quality of life can be restored following double-level osteotomy in varus knee osteoarthritis","volume":"31","author":"C Ihle","year":"2023","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"2309499016684092","DOI":"10.1177\/2309499016684092","article-title":"Comparison of HTO with articular cartilage surgery and UKA in unicompartmental OA","volume":"25","author":"YS Jeon","year":"2017","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s13018-017-0552-9","article-title":"Unicompartmental knee arthroplasty, is it superior to high tibial osteotomy in treating unicompartmental osteoarthritis? A meta-analysis and systemic review","volume":"12","author":"MB Santoso","year":"2017","journal-title":"J Orthop Surg Res"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1111\/j.1445-2197.2007.04021.x","article-title":"Unicompartmental knee arthroplasty for the treatment of unicompartmental osteoarthritis: a systematic study","volume":"77","author":"T Griffin","year":"2007","journal-title":"ANZ J Surg"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1007\/s00167-014-3346-1","article-title":"Clinical outcome after UKA and HTO in ACL deficiency: a systematic review","volume":"24","author":"F Mancuso","year":"2016","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.arth.2013.02.010","article-title":"Comparison of high tibial osteotomy and unicompartmental knee arthroplasty in the treatment of unicompartmental osteoarthritis: a meta-analysis","volume":"28","author":"D Fu","year":"2013","journal-title":"J Arthroplasty"},{"key":"ref41","first-page":"307","article-title":"Unicompartmental Knee Osteoarthritis (UKOA): Unicompartmental Knee Arthroplasty (UKA) or High Tibial Osteotomy (HTO)?","volume":"4","author":"EC Rodriguez-Merchan","year":"2016","journal-title":"Arch Bone Joint Surg"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1007\/s11999-014-3712-9","article-title":"The risk of revision after TKA is affected by previous HTO or UKA","volume":"473","author":"O Robertsson","year":"2015","journal-title":"Clin Orthop Relat Res"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1080\/17453674.2019.1709711","article-title":"Reduced survival of total knee arthroplasty after previous unicompartmental knee arthroplasty compared with previous high tibial osteotomy: a propensity-score weighted mid-term\n          cohort study based on 2,133 observations from the Danish Knee Arthroplasty Registry","volume":"91","author":"A El-Galaly","year":"2020","journal-title":"Acta Orthop"}],"container-title":["Zeitschrift f\u00fcr Orthop\u00e4die und Unfallchirurgie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2120-0993.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T11:21:03Z","timestamp":1730805663000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2120-0993"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,30]]},"references-count":43,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,9,25]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2120-0993","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1864-6697","1864-6743"],"issn-type":[{"value":"1864-6697","type":"print"},{"value":"1864-6743","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,30]]}}}