{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T12:12:03Z","timestamp":1772280723083,"version":"3.50.1"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T00:00:00Z","timestamp":1688428800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Madelung's disease (MD) is a rare disease characterized by diffuse, nonencapsulated, multiple fat masses in different areas of the body. In this case report, we present a case of MD in Asia and its management. A 66-year-old man with a history of hypertension presented with massive growth of soft tissue around the neck, breasts, upper back, and lower abdomen. Preoperative magnetic resonance imaging revealed remarkably hypertrophic fat tissue around the neck and anterior chest was wall, which consistent with the diagnosis of MD. Multiple linear incisions were made on the neck and 763, 186, 635\u2009g of posterior, right, and left fat tissues were excised, respectively. A single wide, transverse incision was done to excise 1,072\u2009g of fat from the upper back. Masses of both breasts were excised, preserving the inferior pedicle, weighing 1,086 (right) and 1,164\u2009g (left). The recovery was optimal and the patient was discharged without complications. In this case, we excised the adipose masses as much as possible and improved contour and symmetry. However, the fat infiltrations in the patient were diffusely distributed, making total fat excision difficult. This rare case report may help in managing patients with MD.<\/jats:p>","DOI":"10.1055\/a-2122-6121","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T22:55:55Z","timestamp":1688511355000},"page":"463-467","source":"Crossref","is-referenced-by-count":3,"title":["A Case Report of Madelung's Disease"],"prefix":"10.1055","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1989-0026","authenticated-orcid":false,"given":"Bo Hyun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9610-7029","authenticated-orcid":false,"given":"Young Mann","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8990-0635","authenticated-orcid":false,"given":"Seong Oh","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4725-772X","authenticated-orcid":false,"given":"Lan Sook","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3365-1232","authenticated-orcid":false,"given":"Youn Hawn","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"key":"ref1","volume-title":"Clinical lectures on surgery, delivered at St. George's Hospital","author":"S B Brodie","year":"1846"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00266-016-0759-x","article-title":"Madelung's disease: revision of 59 surgical cases","volume":"41","author":"C IC Pinto","year":"2017","journal-title":"Aesthetic Plast Surg"},{"issue":"10","key":"ref3","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1007\/s11695-008-9502-2","article-title":"Launois-Bensaude syndrome: an unusual localization of obesity disease","volume":"18","author":"G Verna","year":"2008","journal-title":"Obes Surg"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1172\/JCI108881","article-title":"Multiple symmetric lipomatosis: a defect in 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Li","year":"2022","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/00005792-198401000-00004","article-title":"Multiple symmetric lipomatosis: an updated clinical report","volume":"63","author":"G Enzi","year":"1984","journal-title":"Medicine (Baltimore)"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s00266-004-3123-5","article-title":"Benign symmetric lipomatosis (Madelung's disease): case reports and current management","volume":"28","author":"R Gonz\u00e1lez-Garc\u00eda","year":"2004","journal-title":"Aesthetic Plast Surg"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1007\/s00266-020-02083-5","article-title":"Madelung disease epidemiology and clinical characteristics: a systematic review","volume":"45","author":"Q Liu","year":"2021","journal-title":"Aesthetic Plast 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