{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T19:18:45Z","timestamp":1735586325183,"version":"3.28.0"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Was ist neu?<\/jats:title><jats:p>\n          Endokrinologische Tumorpr\u00e4dispositionen Die Kenntnis \u00fcber eine genetische Tumorpr\u00e4disposition hat einen wesentlichen Einfluss auf die Behandlung sowie die Fr\u00fcherkennung und Pr\u00e4vention bei Patient*innen mit endokrinen Tumoren. Die im Rahmen einer famili\u00e4ren Pr\u00e4disposition entstehenden Tumore manifestieren sich oft fr\u00fch und betreffen h\u00e4ufig mehrere endokrine Organe. Im folgenden Artikel werden die innerhalb der Tumorsyndrome h\u00e4ufig vorkommenden Krankheitsbilder wie die MEN-Syndrome (Multiple Endokrine Neoplasien) sowie seltenere Manifestationen wie das famili\u00e4re isolierte Hypophysenadenom (FIPA) anhand ihrer jeweiligen Indikator-Erkrankungen vorgestellt. <\/jats:p>","DOI":"10.1055\/a-2131-2450","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:29:48Z","timestamp":1709080188000},"page":"283-289","source":"Crossref","is-referenced-by-count":1,"title":["Tumorpr\u00e4disposition in der Endokrinologie \u2013 von MEN bis FIPA"],"prefix":"10.1055","volume":"149","author":[{"given":"Lina","family":"Jegodzinski","sequence":"additional","affiliation":[{"name":"Medizinische Klinik 1, Bereich Endokrinologie und Diabetologie, Universit\u00e4tsklinikum Schleswig Holstein, Campus L\u00fcbeck, L\u00fcbeck"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Gebauer","sequence":"additional","affiliation":[{"name":"Medizinische Klinik 1, Bereich Endokrinologie und Diabetologie, Universit\u00e4tsklinikum Schleswig Holstein, Campus L\u00fcbeck, L\u00fcbeck"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,27]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3390\/genes14051025","article-title":"Hereditary Cancer Syndromes: A Comprehensive Review with a Visual Tool","volume":"14","author":"M Garutti","year":"2023","journal-title":"Genes (Basel)"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1038\/nature21063","article-title":"Whole-genome landscape of pancreatic neuroendocrine tumours","volume":"543","author":"A Scarpa","year":"2017","journal-title":"Nature"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1210\/er.2012-1013","article-title":"Familial isolated pituitary adenomas (FIPA) and the pituitary adenoma predisposition due to mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene","volume":"34","author":"A Beckers","year":"2013","journal-title":"Endocr Rev"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1955","DOI":"10.1210\/jc.2013-3826","article-title":"Acromegaly and McCune-Albright syndrome","volume":"99","author":"S Salenave","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e389708","DOI":"10.1200\/EDBK_389708","article-title":"Papaleontiou M. 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