{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T10:12:33Z","timestamp":1693649553754},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n            Anamnese und klinischer Befund Ein 20-j\u00e4hriger Patient stellte sich mit gro\u00dffl\u00e4chigen und \u00e4u\u00dferst schmerzhaften Purpura mit Nekrosearealen und Vesikeln, vor allem an den unteren Extremit\u00e4ten, aber auch an den Armen, am Stamm und an den Ohren in unserer Notaufnahme vor. Vorbestehend war ein Konsum von Kokain.<\/jats:p><jats:p>\n            Untersuchungen In den Laboruntersuchungen zeigten sich erh\u00f6hte Entz\u00fcndungszeichen sowie eine Erh\u00f6hung der Proteinase 3- und Myeloperoxidase-ANCA (Anti-Neutrophile cytoplasmatische Antik\u00f6rper).<\/jats:p><jats:p>\n            Diagnose In Zusammenschau der Anamnese, des klinischen Befundes und der Laborwerte zeigte sich eine Vaskulitis der Haut nach Kokainkonsum.<\/jats:p><jats:p>\n            Therapie und Verlauf Unter einer Therapie mit Steroid sowie Drogenkarenz kam es zu einer R\u00fcckbildung der Ver\u00e4nderungen.<\/jats:p><jats:p>\n            Folgerung Die Vaskulitis ist eine schwerwiegende Komplikation der Einnahme von Kokain.<\/jats:p>","DOI":"10.1055\/a-2142-1530","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T22:37:27Z","timestamp":1693607847000},"page":"1182-1186","source":"Crossref","is-referenced-by-count":0,"title":["Vaskulitis der Haut nach Kokainkonsum"],"prefix":"10.1055","volume":"148","author":[{"given":"Rubi Stephani","family":"Hellwege","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Intensivmedizin, Universit\u00e4tsspital Z\u00fcrich,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Sitter","sequence":"additional","affiliation":[{"name":"Medizinische Klinik und Poliklinik IV, LMU Klinikum Campus Innenstadt, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"W\u00f6rnle","sequence":"additional","affiliation":[{"name":"Zentrale Notaufnahme, LMU Klinikum Campus Innenstadt, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, M\u00fcnchen, 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