{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:14Z","timestamp":1740126854256,"version":"3.37.3"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003Coronavirus disease 2019 (COVID-19) generally causes milder illness in the pediatric population. However, infants represent a higher-risk population with evolving symptomatology and severity. There is a paucity of large population-based data on the impact of COVID-19 on hospitalized infants.<\/jats:p><jats:p>\n            Study Design\u2003In this large cohort study, the National Inpatient Sample database was queried for all infant hospital admissions between January and December 2020 in the United States, with and without a diagnosis of COVID-19 based on ICD-10-CM U07. The mortality and morbidity of infants with and without COVID-19 were evaluated. Parent-reported race and outcomes were also analyzed.<\/jats:p><jats:p>\n            Results\u2003A weighted total of 3,754,236 infants who were hospitalized were identified, of which 4,265 patients (0.11%) had a concomitant diagnosis of COVID-19. Infants with COVID-19 had similar mortality and extracorporeal membrane oxygenation utilization. Infants with concomitant COVID-19 had a higher rate of respiratory failure, congestive heart failure, acute kidney injury, and coagulopathy. Compared with Caucasian infants and Asian infants, Hispanic and African American infants were more likely to have COVID-19 hospital admissions than hospitalizations without COVID-19 diagnosis. Patients with lower median household income represented the majority of the COVID-19 hospitalization. The infants with COVID-19 were more likely to have Medicaid or Medicare insurance and less likely to have private insurance.<\/jats:p><jats:p>\n            Conclusion\u2003In this large cohort of hospitalized infants with COVID-19, the infection was associated with complications, including respiratory failure and endotracheal intubations but not associated with a higher risk for mortality. Infants from racial minorities and lower socioeconomic strata carry the highest burden of COVID-19 infection.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2149-8810","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T23:03:28Z","timestamp":1691449408000},"page":"e2727-e2734","source":"Crossref","is-referenced-by-count":1,"special_numbering":"S","title":["Nationwide Analysis of the Outcomes and Mortality of Hospitalized Infants with Concomitant Diagnosis of COVID-19"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7278-0565","authenticated-orcid":false,"given":"Parvathy","family":"Krishnan","sequence":"additional","affiliation":[{"name":"Department of Neonatal-Perinatal Medicine, Westchester Medical Center and New York Medical College, Valhalla, New 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York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lance","family":"Parton","sequence":"additional","affiliation":[{"name":"Department of Neonatal-Perinatal Medicine, Westchester Medical Center and New York Medical College, Valhalla, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Chandrasekharan","sequence":"additional","affiliation":[{"name":"Department of Neonatal-Perinatal Medicine, University at Buffalo, Kaleida Health, UBMD Pediatrics, Buffalo, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meenakshi","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neonatal-Perinatal Medicine, Westchester Medical Center and New York Medical College, Valhalla, New 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