{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T23:10:24Z","timestamp":1746573024229,"version":"3.37.3"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Padiatr"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective Exercise induced laryngeal obstruction (EILO) is an important\n                    differential diagnosis to exercise induced bronchoconstriction (EIB) and\n                    diagnosed via continuous laryngoscopy while exercising (CLE). However,\n                    availability of CLE is limited to specialized centres. And without CLE EILO is\n                    often misdiagnosed as EIB. Therefore it is essential to carefully preselect\n                    potential EILO candidates. Aim of this study was to investigate whether two\n                    short questionnaires -Asthma Control Test (ACT) and Dyspnea Index (DI)\n                    evaluating upper airway-related dyspnea- can differentiate between EIB and\n                    EILO.<\/jats:p><jats:p>\n          Methods Patients with dyspnea while exercising were analysed with an\n                    exercise challenge in the cold chamber (ECC) to diagnose EIB in visit 1 (V1), as\n                    appropriate a CLE in visit 2 (V2, 4\u20136 weeks after V1) and ACT and DI in\n                    V1 and V2. EIB patients were treated with asthma medication after V1.<\/jats:p><jats:p>\n          Results Complete dataset of 36 subjects were gathered. The ACT showed\n                    lower values in V2 in EILO compared to EIB patients. A lack of improvement in\n                    ACT in V2 after asthma medication of EIB patients is suspicious for additional\n                    EILO diagnosis. The DI showed higher values in V1 in EILO compared to EIB\n                    patients. A score\u226530 can predict a positive CLE reaction.<\/jats:p><jats:p>\n          Conclusion ACT and DI are valuable tools in preselecting CLE candidates to\n                    assure timely diagnostic despite limited diagnostic capabilities.<\/jats:p>","DOI":"10.1055\/a-2151-2269","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:21:33Z","timestamp":1706574093000},"page":"139-144","source":"Crossref","is-referenced-by-count":2,"title":["Are Questionnaires Helpful To Predict Exercise-Induced\n                    Bronchoconstriction (EIB) And Exercise-Induced Laryngeal Obstruction\n                    (EILO)?"],"prefix":"10.1055","volume":"236","author":[{"given":"Melanie","family":"Dre\u00dfler","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Lassmann","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celine","family":"Eichhorn","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordis","family":"Trischler","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7455-8037","authenticated-orcid":false,"given":"Martin","family":"Hutter","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Zielen","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Schulze","sequence":"additional","affiliation":[{"name":"Goethe-University Frankfurt, University Hospital, Department of\n                    Pediatrics, Pneumology, Allergology, Infectious Diseases, Gastroenterology,\n                    Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1164\/rccm.201303-0437ST","article-title":"An official American Thoracic Society clinical practice guideline:\n                    Exercise-induced bronchoconstriction","volume":"187","author":"J P Parsons","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1007\/s00405-011-1612-0","article-title":"Exercise-induced laryngeal obstructions: prevalence and symptoms in the general\n                    public","volume":"268","author":"P M Christensen","year":"2011","journal-title":"Eur Arch 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Pediatr"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1002\/ppul.23634","article-title":"Therapeutic laryngoscopy during exercise: A novel non-surgical therapy for\n                    refractory EILO","volume":"52","author":"J T Olin","year":"2017","journal-title":"Pediatr Pulmonol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1007\/s00405-011-1656-1","article-title":"Exercise-induced laryngeal obstruction: natural history and effect of surgical\n                    treatment","volume":"268","author":"R C Maat","year":"2011","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3389\/fsurg.2019.00044","article-title":"Severe Exercise-Induced Laryngeal Obstruction Treated With\n                    Supraglottoplasty","volume":"6","author":"A Sandnes","year":"2019","journal-title":"Front Surg"}],"container-title":["Klinische 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