{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:03:03Z","timestamp":1791975783899,"version":"4.4.0"},"reference-count":47,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to investigate the acute effects of autoregulated and\n                    non-autoregulated applied pressures during blood flow restriction resistance\n                    exercise to volitional fatigue on indices of arterial stiffness using the Delfi\n                    Personalized Tourniquet System. Following a randomized autoregulated or\n                    non-autoregulated blood flow restriction familiarization session, 20 physically\n                    active adults (23\u00b15 years; 7 females) participated in three randomized\n                    treatment-order sessions with autoregulated and non-autoregulated and no blood\n                    flow restriction training. Participants performed four sets of dumbbell wall\n                    squats to failure using 20% of one repetition maximum. Blood flow\n                    restriction was performed with 60% of supine limb occlusion pressure.\n                    Testing before and post-session included an ultrasonic scan of the carotid\n                    artery, applanation tonometry, and blood pressure acquisition.<\/jats:p><jats:p>Carotid-femoral pulse wave velocity increased in the non-autoregulated and no\n                    blood flow restriction training groups following exercise while carotid-radial\n                    pulse wave velocity increased in the no blood flow restriction training group\n                    (all p&lt;0.05). Carotid-femoral pulse wave velocity exhibited an\n                    interaction effect between autoregulated and non-autoregulated blood flow\n                    restriction in favor of autoregulated blood flow restriction (p&lt;0.05).\n                    Autoregulated blood flow restriction training does not influence indices of\n                    arterial stiffness while non-autoregulated and no blood flow restriction\n                    training increases central stiffness.<\/jats:p>","DOI":"10.1055\/a-2152-0015","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T23:09:11Z","timestamp":1691708951000},"page":"23-32","source":"Crossref","is-referenced-by-count":22,"title":["Autoregulated and Non-Autoregulated Blood Flow Restriction on Acute\n                    Arterial Stiffness"],"prefix":"10.1055","volume":"45","clinical-trial-number":[{"clinical-trial-number":"nct05719090","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Nicholas","family":"Rolnick","sequence":"additional","affiliation":[{"name":"Exercise Science, Lehman College, Bronx, United States"},{"name":"Physical Therapy, The Human Performance Mechanic, Manhattan, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Licameli","sequence":"additional","affiliation":[{"name":"Physical Therapy, Strength Together, Inc., Nutley, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoud","family":"Moghaddam","sequence":"additional","affiliation":[{"name":"Physical Therapy, University of Maryland Eastern Shore, Princess Anne,\n                    United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Marquette","sequence":"additional","affiliation":[{"name":"Exercise Science, Salisbury University, Salisbury, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Walter","sequence":"additional","affiliation":[{"name":"Exercise Science, Salisbury University, Salisbury, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent","family":"Fedorko","sequence":"additional","affiliation":[{"name":"Exercise Science, Salisbury University, Salisbury, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Werner","sequence":"additional","affiliation":[{"name":"Exercise Science, Salisbury University, Salisbury, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"882472","DOI":"10.3389\/fphys.2022.882472","article-title":"Current trends in blood flow restriction","volume":"13","author":"M Cuffe","year":"2022","journal-title":"Front Physiol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s40279-017-0795-y","article-title":"Magnitude of muscle strength and mass adaptations between high-load resistance\n                    training versus low-load resistance training associated with blood-flow\n                    restriction: A systematic review and meta-analysis","volume":"48","author":"M E Lixandrao","year":"2018","journal-title":"Sports Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/sms.13632","article-title":"Effect of blood-flow restricted vs heavy-load strength training on muscle\n                    strength: Systematic review and meta-analysis","volume":"30","author":"B M Gronfeldt","year":"2020","journal-title":"Scand J Med Sci Sports"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"H90","DOI":"10.1152\/ajpheart.00468.2019","article-title":"Clinical safety of blood flow-restricted training? A comprehensive review of\n                    altered muscle metaboreflex in cardiovascular disease during ischemic\n                    exercise","volume":"318","author":"M Cristina-Oliveira","year":"2020","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1177\/0363546519882652","article-title":"The safety of blood flow restriction training as a therapeutic intervention for\n                    patients with musculoskeletal disorders: A systematic review","volume":"48","author":"M C Minniti","year":"2020","journal-title":"Am J Sports Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/sms.13902","article-title":"Low-intensity resistance exercise with blood flow restriction and arterial\n                    stiffness in humans: A systematic review","volume":"31","author":"S Amorim","year":"2021","journal-title":"Scand J Med Sci Sports"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","article-title":"Expert consensus document on arterial stiffness: methodological issues and\n                    clinical applications","volume":"27","author":"S Laurent","year":"2006","journal-title":"Eur Heart J"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1161\/CIRCRESAHA.121.318061","article-title":"Arterial stiffness and cardiovascular risk in hypertension","volume":"128","author":"P Boutouyrie","year":"2021","journal-title":"Circ Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1152\/physrev.00014.2016","article-title":"Vascular adaptation to exercise in humans: role of hemodynamic stimuli","volume":"97","author":"D J Green","year":"2017","journal-title":"Physiol Rev"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1046\/j.1523-1755.2003.00932.x","article-title":"Aortic pulse wave velocity index and mortality in end-stage renal disease","volume":"63","author":"J Blacher","year":"2003","journal-title":"Kidney Int"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/cpf.12245","article-title":"Haemodynamic responses during resistance exercise with blood flow restriction in\n                    hypertensive subjects","volume":"36","author":"R R Pinto","year":"2016","journal-title":"Clin Physiol Funct Imaging"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3831\/KPI.2017.20.002","article-title":"Restricted blood flow exercise in sedentary, overweight african-american females\n                    may increase muscle strength and decrease endothelial function and vascular\n                    autoregulation","volume":"20","author":"V Bond","year":"2017","journal-title":"J Pharmacopuncture"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e006427","DOI":"10.1161\/CIRCHEARTFAILURE.119.006427","article-title":"Effect of blood flow restricted resistance exercise and remote ischemic\n                    conditioning on functional capacity and myocellular adaptations in patients with\n                    heart failure","volume":"12","author":"T Groennebaek","year":"2019","journal-title":"Circ Heart Fail"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1249\/MSS.0b013e3181909d9d","article-title":"Hemodynamic and vascular response to resistance exercise with L-arginine","volume":"41","author":"C A Fahs","year":"2009","journal-title":"Med Sci Sports Exerc"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s11332-021-00748-5","article-title":"K T. 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A randomized clinical trial","volume":"19","author":"J B Barbosa","year":"2018","journal-title":"J Vasc Access"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"H357","DOI":"10.1152\/ajpheart.00039.2018","article-title":"Effect of sex, menstrual cycle phase, and monophasic oral contraceptive pill use\n                    on local and central arterial stiffness in young adults","volume":"315","author":"S E Priest","year":"2018","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s00421-018-3815-1","article-title":"Menstrual phase and the vascular response to acute resistance exercise","volume":"118","author":"J A Augustine","year":"2018","journal-title":"Eur J Appl Physiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1161\/HYPERTENSIONAHA.109.137703","article-title":"Arterial wave reflections during the menstrual cycle of healthy women: A\n                    reproducibility study","volume":"54","author":"T G Papaioannou","year":"2009","journal-title":"Hypertension"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s00421-015-3304-8","article-title":"Muscle damage and repeated bout effect following blood flow restricted\n                    exercise","volume":"116","author":"P Sieljacks","year":"2016","journal-title":"Eur J Appl Physiol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3390\/jcm10020291","article-title":"The acute effect of exercise on arterial stiffness in healthy subjects: A\n                    meta-analysis","volume":"10","author":"A Saz-Lara","year":"2021","journal-title":"J Clin Med"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"533","DOI":"10.3389\/fphys.2019.00533","article-title":"Blood flow restriction exercise: considerations of methodology, application, and\n                    safety","volume":"10","author":"S D Patterson","year":"2019","journal-title":"Front Physiol"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0000000000004093","article-title":"Repetition failure occurs earlier during low-load resistance exercise with high\n                    but not low blood flow restriction pressures: A systematic review and\n                    meta-analysis","author":"M S Cerqueira","year":"2021","journal-title":"J Strength Cond Res"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"e4697","DOI":"10.7717\/peerj.4697","article-title":"Influence and reliability of lower-limb arterial occlusion pressure at different\n                    body positions","volume":"6","author":"L Hughes","year":"2018","journal-title":"PeerJ"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00421-017-3770-2","article-title":"Body position influences arterial occlusion pressure: implications for the\n                    standardization of pressure during blood flow restricted exercise","volume":"118","author":"P Sieljacks","year":"2018","journal-title":"Eur J Appl Physiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1007\/s40846-016-0173-5","article-title":"Technique for measuring limb occlusion pressure that facilitates personalized\n                    tourniquet systems: a randomized trial","volume":"36","author":"B A Masri","year":"2016","journal-title":"J Med Biol Eng"},{"key":"ref37","first-page":"45","article-title":"Blood flow restriction therapy: The essential value of accurate surgical-grade\n                    tourniquet autoregulation","author":"TH L Lai","year":"2023","journal-title":"CMBES Proceedings"},{"key":"ref38","volume-title":"National Strength & Conditioning Association (U.S.). 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