{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T05:30:08Z","timestamp":1730871008441,"version":"3.28.0"},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Cavernous sinus meningiomas (CSMs) are challenging given their proximity to neurovascular structures. Treatments include surgery, radiation, or observation. There are little data comparing outcomes based on treatment. This study presents the radiographic and functional outcomes of patients with CSMs treated with either radiation, surgical resection\u2009\u00b1\u2009radiation, or radiographic surveillance.<\/jats:p><jats:p>\n          Methods\u2003This is a retrospective review of adults diagnosed with CSMs between 2009 and 2016. Patient and tumor characteristics and outcomes were obtained from chart review. Categorical and continuous variables were compared via nonparametric tests.<\/jats:p><jats:p>\n          Results\u2003Sixty-four patients were diagnosed with CSMs between 2009 and 2016. Thirty-four had radiation. Thirteen had surgical resection with adjuvant radiation and 14 underwent observation.<\/jats:p><jats:p>Fifty-four patients had a pretreatment deficit (84.4%). Radiographic control rates were 100% in the surgery group, 97.1% in the radiation group, 69.2% in the surgery\u2009+\u2009adjuvant radiation, and 90.9% in the observation group (p\u2009=\u20090.035). The radiotherapy group had complete improvement of symptoms in 32.4% and partial improvement in 23.1% (p\u2009=\u20090.022). In the surgery group, one patient had complete resolution of symptoms (6.3%), eight had partial improvement (50.0%), and seven patients had no improvement (p\u2009=\u20090.002). Surgery was more likely to lead to progression of symptoms posttreatment (odds ratio: 5.16, confidence interval: 1.309\u201320.34) (p\u2009=\u20090.019).<\/jats:p><jats:p>\n          Conclusion\u2003Radiation has an excellent rate of radiographic control. Surgery is an option for large or symptomatic lesions. The role of surgery is primarily for vision preservation, decompression of cranial nerves, and tumor debulking and patients should be counseled extensively regarding treatment goals and expectations prior to surgery.<\/jats:p>","DOI":"10.1055\/a-2158-6321","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T23:11:42Z","timestamp":1692745902000},"page":"635-640","source":"Crossref","is-referenced-by-count":0,"title":["Functional and Radiographic Outcomes of Cavernous Meningiomas Based on Treatment Modality"],"prefix":"10.1055","volume":"85","author":[{"given":"Brandon","family":"Laing","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Feller","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall","family":"Treffy","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Montoure","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Washington, Seattle, Washington, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Best","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan T.","family":"Zwagerman","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,9,25]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1055\/s-0039-1683430","article-title":"Stereotactic radiosurgery of cavernous sinus meningiomas","volume":"81","author":"D Rue\u00df","year":"2020","journal-title":"J Neurol Surg B Skull Base"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3171\/2018.10.JNS181480","article-title":"Outcomes of decompressive surgery for cavernous sinus meningiomas: long-term follow-up in 50 patients","volume":"132","author":"Y M Gozal","year":"2020","journal-title":"J Neurosurg"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"937","DOI":"10.3171\/JNS-07\/11\/0937","article-title":"Long-term follow-up of meningiomas of the cavernous sinus after surgical treatment alone","volume":"107","author":"M 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Maruyama","year":"2004","journal-title":"Neurosurgery"},{"issue":"02","key":"ref7","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/00006123-199702000-00003","article-title":"The surgical resectability of meningiomas of the cavernous sinus","volume":"40","author":"M G O'Sullivan","year":"1997","journal-title":"Neurosurgery"},{"issue":"04","key":"ref8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000478024","article-title":"Gamma knife radiosurgery for cavernous sinus meningiomas: analysis of outcome in 166 patients","volume":"95","author":"M Azar","year":"2017","journal-title":"Stereotact Funct Neurosurg"}],"container-title":["Journal of Neurological Surgery Part B: Skull 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