{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:47:10Z","timestamp":1789757230401,"version":"4.0.1"},"reference-count":50,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Chronic inflammation is a common factor in obesity, diabetes mellitus, and the\n                    complications of diabetes, including diabetic wounds. These ulcers are\n                    characterized by persistent lesions that are challenging to heal, significantly\n                    decreasing patients\u2019 quality of life and imposing a substantial\n                    financial burden on society. MMP are zinc endopeptidases that play a role in\n                    wound healing in response to various stimuli, including diabetes mellitus. MMP\n                    levels fluctuate throughout the wound healing process in diabetic\n                    patients' serum, skin tissues, and wound fluid, indicating their\n                    potential as biomarkers for diabetic foot ulcers. Targeting MMP has emerged as a\n                    promising strategy for treating diabetic wounds, as these enzymes are involved\n                    in critical biological processes related to wound healing, including\n                    extracellular matrix secretion, angiogenesis, granulation tissue formation,\n                    collagen growth, re-epithelization, inflammatory response, and oxidative\n                    stress.<\/jats:p>","DOI":"10.1055\/a-2171-5879","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T01:47:58Z","timestamp":1696556878000},"page":"752-757","source":"Crossref","is-referenced-by-count":20,"title":["Based on Clinical Research Matrix Metalloprotease (MMP) Inhibitors to\n                    Promote Diabetic Wound Healing"],"prefix":"10.1055","volume":"55","author":[{"given":"Jagat Pal","family":"Yadav","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences, Rama University, Kanpur,\n                    India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.diabres.2011.10.029","article-title":"IDF Diabetes Atlas: global estimates of the prevalence of diabetes for 2011 and\n                    2030","volume":"94","author":"D R Whiting","year":"2011","journal-title":"Diabetes Res Clin Pract"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"e202200200","DOI":"10.1002\/cbdv.202200200","article-title":"Cucumis melo var. momordica as a potent antidiabetic, antioxidant and possible\n                    anticovid alternative: investigation through experimental and computational\n                    methods","volume":"19","author":"J P Yadav","year":"2022","journal-title":"Chem 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