{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:00Z","timestamp":1740126840298,"version":"3.37.3"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n            Purpose To assess splenic involvement using B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) compared with standard imaging with contrast-enhanced computerized tomography (CT) \/ 18-fluorodeoxyglucose positron-emission tomography (PET-CT) in patients with Hodgkin lymphoma.<\/jats:p><jats:p>\n            Materials and Methods Imaging data from 112 patients from 12\/2003 to 10\/2022 with histologically confirmed Hodgkin lymphoma during staging or relapse were analyzed for splenic lymphoma involvement. In all patients, standard imaging (CT\/PET-CT), along with B-mode US and CEUS examinations, was performed. Evidence of focal splenic lesions (FSLs) found by imaging procedures was suggestive of splenic involvement. Follow-up imaging was performed in each patient after treatment, and treatment response indicated definitive splenic involvement.<\/jats:p><jats:p>\n            Results 40 patients (35.7%) were identified by imaging modalities as having splenic involvement, which was confirmed by response during follow-up. Standard CT\/PET-CT imaging detected splenic involvement in 36\/112 patients (32.1%). FSLs were detected with B-mode US in 38 patients (33.9%) and CEUS in 36 patients (32.1%). The sensitivity of standard imaging, B-mode US, and CEUS was 90%, 95%, and 90%, respectively.<\/jats:p><jats:p>\n            Conclusion B-mode US examination is a diagnostic method used in addition to standard imaging for the detection of splenic involvement in Hodgkin lymphoma. CEUS does not provide additional benefit compared to B-mode US and the standard reference procedure.<\/jats:p>","DOI":"10.1055\/a-2173-2361","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T22:36:00Z","timestamp":1697841360000},"page":"484-492","source":"Crossref","is-referenced-by-count":0,"title":["B-Mode Ultrasound and Contrast-Enhanced Ultrasound for the Detection of Splenic Involvement in Hodgkin Lymphoma: A Retrospective Analysis of 112 Patients"],"prefix":"10.1055","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0180-5452","authenticated-orcid":false,"given":"Hajo","family":"Findeisen","sequence":"additional","affiliation":[{"name":"Department for Internal Medicine, Red Cross Hospital Bremen, Bremen, Germany"},{"name":"Interdisciplinary Center of Ultrasound Diagnostics, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"G\u00f6rg","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center of Ultrasound Diagnostics; Gastroenterology, Endocrinology, Metabolism and Clinical Infectiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Winter","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center of Ultrasound Diagnostics, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4573-7802","authenticated-orcid":false,"given":"Corinna","family":"Trenker","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center of Ultrasound Diagnostics; Department of Hematology, Oncology and Immunology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6015-6347","authenticated-orcid":false,"given":"Christoph F.","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Department General Internal Medicine, Kliniken Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1308-988X","authenticated-orcid":false,"given":"Amjad","family":"Alhyari","sequence":"additional","affiliation":[{"name":"Interdisciplinary Center of Ultrasound Diagnostics; 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