{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T17:47:06Z","timestamp":1770227226275,"version":"3.49.0"},"reference-count":64,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Das autoimmune polyendokrine Syndrom (APS) ist eine beim Hund selten vorkommende\n                    Kombination autoimmun bedingter endokriner Erkrankungen. H\u00e4ufige\n                    Kombinationen sind Hypothyreose mit Hypoadrenokortizismus oder Diabetes\n                    mellitus. Des Weiteren k\u00f6nnen seltener Hypoparathyreoidismus und\n                    Orchitis als Teil eines APS auftreten. Die Diagnose des APS erfolgt \u00fcber\n                    die Diagnose der jeweiligen Erkrankungen. Ebenso besteht die Therapie des APS in\n                    der Therapie der beteiligten Erkrankungen, d.h. in der Substitution der\n                    defizienten Hormone. Entstehen unter einer zuvor stabilen Therapie einer\n                    endokrinen Erkrankung weitere Symptome (z.B. Polyurie, Polydipsie oder\n                    Gewichtsverlust), sollte an die zus\u00e4tzliche Entstehung anderer\n                    Endokrinopathien wie Hypoadrenokortizismus oder Diabetes mellitus gedacht\n                    werden. Die Diagnose der initial diagnostizierten Endokrinopathie sollte jedoch\n                    ebenfalls kritisch hinterfragt werden. Dieser Artikel fasst Fallberichte aus dem\n                    eigenen Patientengut sowie ausgew\u00e4hlte Fallberichte aus der Literatur\n                    mit ihren Besonderheiten zusammen.<\/jats:p>","DOI":"10.1055\/a-2183-0654","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T23:30:31Z","timestamp":1699918231000},"page":"313-325","source":"Crossref","is-referenced-by-count":2,"title":["Polyendokrine Syndrome beim Hund"],"prefix":"10.1055","volume":"51","author":[{"given":"Sina","family":"Strey","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintiere, Stiftung Tier\u00e4rztliche\n                    Hochschule Hannover, Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Mischke","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintiere, Stiftung Tier\u00e4rztliche\n                    Hochschule Hannover, Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Rieder","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kleintiere, Stiftung Tier\u00e4rztliche\n                    Hochschule Hannover, Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,11,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1056\/NEJMra030158","article-title":"Autoimmune polyendocrine syndromes","volume":"350","author":"G S Eisenbarth","year":"2004","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1056\/NEJMra1713301","article-title":"Autoimmune polyendocrine syndromes","volume":"378","author":"E S Husebye","year":"2018","journal-title":"N Engl J Med"},{"key":"ref3","first-page":"485","volume-title":"Hypoadrenocorticism. 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