{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T08:16:18Z","timestamp":1783671378101,"version":"3.55.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"S 01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>\n            Objective\u2003The benefit of mechanical ripening agents following preterm premature rupture of membranes (PPROM) has not been established. We sought to compare the time to delivery in women who received transcervical Foley catheter plus oxytocin infusion versus oxytocin infusion alone in patients with unfavorable cervices and PPROM.<\/jats:p><jats:p>\n            Study Design\u2003This is a retrospective cohort study of patients presenting with PPROM of a live, singleton gestation between 240\/7 and 366\/7 weeks' gestation from January 2005 to October 2018 at a single, tertiary care institution. Patients with an unfavorable cervical examination (\u22642-cm dilation), no contraindication to labor and undergoing labor induction were analyzed. Time to delivery was analyzed using multivariable linear regression adjusting for cervical dilation at induction and nulliparity. Bivariate and multivariate analyses were used where appropriate.<\/jats:p><jats:p>\n            Results\u2003A total of 260 participants were included: 109 who received a Foley catheter and oxytocin (Foley\/oxytocin) and 151 who had oxytocin alone. Demographic characteristics were similar between the two groups. Unadjusted time to delivery was significantly shorter in the oxytocin only group (Foley\/oxytocin: 20.35\u2009hours vs. oxytocin alone: 14.7\u2009hours, p\u2009&lt;\u20090.001). No differences in length of labor were detected after adjusting for cervical dilation at induction and nulliparity (p\u2009=\u20090.5). The unadjusted rate of cesarean delivery was higher in the combination Foley\/oxytocin group (Foley\/oxytocin: 16.5% vs. oxytocin alone: 7.3%, p\u2009=\u20090.03), but no differences were found in the adjusted analysis (p\u2009=\u20090.06). There were no differences in clinical chorioamnionitis rates between the two groups (Foley\/oxytocin: 8.3% vs. oxytocin alone: 9.3%, p\u2009=\u20090.83). Furthermore, no significant differences were found in maternal and neonatal outcomes between the two groups.<\/jats:p><jats:p>\n            Conclusion\u2003In patients with PROM, the use of a transcervical Foley catheter in addition to oxytocin is not associated with a shorter time to delivery compared with oxytocin alone.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/a-2185-4102","type":"journal-article","created":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T22:59:01Z","timestamp":1696460341000},"page":"e3030-e3034","source":"Crossref","is-referenced-by-count":2,"special_numbering":"S","title":["Combination Foley Catheter\u2013Oxytocin versus Oxytocin Alone following Preterm Premature Rupture of Membranes"],"prefix":"10.1055","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5354-3442","authenticated-orcid":false,"given":"Helen B.","family":"Gomez Slagle","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Columbia University Irving Medical Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2927-8693","authenticated-orcid":false,"given":"Matthew K.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Christiana Care Health System, Newark, Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony C.","family":"Sciscione","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Christiana Care Health System, Newark, Delaware"},{"name":"Department of Maternal\u2014Fetal Medicine, Delaware Center for Maternal Fetal Medicine, Newark, Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwan","family":"Ma'ayeh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Christiana Care Health System, Newark, Delaware"},{"name":"Department of Maternal\u2014Fetal Medicine, Delaware Center for Maternal Fetal Medicine, Newark, Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,11,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jpeds.2016.11.074","article-title":"Impact of latency duration on the prognosis of preterm infants after preterm premature rupture of membranes at 24 to 32 weeks' gestation: a national population-based cohort study","volume":"182","author":"E Lorthe","year":"2017","journal-title":"J Pediatr"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1097\/AOG.0000000000002663","article-title":"ACOG practice bulletin no. 188: prelabor rupture of membranes","volume":"131","author":"K Kuba","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"12","key":"ref3","first-page":"998","article-title":"[Preterm premature rupture of membranes: CNGOF guidelines for clinical practice - Short version]","volume":"46","author":"T Schmitz","year":"2018","journal-title":"Gyn\u00e9col Obst\u00e9t Fertil S\u00e9nol"},{"issue":"12","key":"ref4","first-page":"1068","article-title":"Modalities of birth in case of uncomplicated preterm premature rupture of membranes: CNGOF Preterm Premature Rupture of Membranes Guidelines [in French]","volume":"46","author":"P Delorme","year":"2018","journal-title":"Gyn\u00e9col Obst\u00e9t Fertil S\u00e9nol"},{"issue":"06","key":"ref5","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1097\/AOG.0000000000001778","article-title":"Mechanical and pharmacologic methods of labor induction: a randomized controlled trial","volume":"128","author":"L D Levine","year":"2016","journal-title":"Obstet Gynecol"},{"issue":"09","key":"ref6","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1111\/1471-0528.13981","article-title":"Methods to induce labour: a systematic review, network meta-analysis and cost-effectiveness analysis","volume":"123","author":"Z Alfirevic","year":"2016","journal-title":"BJOG"},{"issue":"14","key":"ref7","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.3109\/14767058.2015.1086331","article-title":"Controlled-release dinoprostone insert versus Foley catheter for labor induction: a meta-analysis","volume":"29","author":"H Wang","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/AOG.0000000000001002","article-title":"Evaluation of a transcervical foley catheter as a source of infection: a systematic review and meta-analysis","volume":"126","author":"K McMaster","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"09","key":"ref9","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1055\/s-0036-1580608","article-title":"Foley catheter or oral misoprostol for induction of labor in women with term premature rupture of membranes: a randomized multicenter trial","volume":"33","author":"H Kruit","year":"2016","journal-title":"Am J Perinatol"},{"issue":"06","key":"ref10","doi-asserted-by":"crossref","first-page":"967","DOI":"10.3109\/14767058.2015.1027191","article-title":"Use of intracervical balloons and chorioamnionitis in term premature rupture of membranes","volume":"29","author":"I B Cabrera","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"360.e1","DOI":"10.1016\/j.ajog.2017.04.038","article-title":"A randomized trial of foley bulb for labor induction in premature rupture of membranes in nulliparas (FLIP)","volume":"217","author":"J MH Amorosa","year":"2017","journal-title":"Am J Obstet Gynecol"},{"issue":"04","key":"ref12","doi-asserted-by":"crossref","first-page":"e1001208","DOI":"10.1371\/journal.pmed.1001208","article-title":"Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks: a randomized controlled trial","volume":"9","author":"D P van der Ham","year":"2012","journal-title":"PLoS Med"},{"issue":"04","key":"ref13","doi-asserted-by":"crossref","first-page":"276.e1","DOI":"10.1016\/j.ajog.2012.07.024","article-title":"Management of late-preterm premature rupture of membranes: the PPROMEXIL-2 trial","volume":"207","author":"D P van der Ham","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0140-6736(15)00724-2","article-title":"Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial","volume":"387","author":"J M Morris","year":"2016","journal-title":"Lancet"},{"issue":"01","key":"ref15","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/AOG.0000000000002374","article-title":"Foley plus oxytocin compared with oxytocin for induction after membrane rupture: a randomized controlled trial","volume":"131","author":"A D Mackeen","year":"2018","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2185-4102.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T13:46:08Z","timestamp":1730814368000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2185-4102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,4]]},"references-count":15,"journal-issue":{"issue":"S 01","published-online":{"date-parts":[[2024,5,13]]},"published-print":{"date-parts":[[2024,5]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2185-4102","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10,4]]},"published":{"date-parts":[[2023,10,4]]}}}