{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T05:10:45Z","timestamp":1781759445762,"version":"3.54.5"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg G Grosstiere Nutztiere"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective This retrospective evaluation of data from a large commercial\n                    embryo transfer facility aimed to determine the extent to which age and\n                    treatment on the day of embryo transfer in recipient mares influence the\n                    likelihood of pregnancy.<\/jats:p><jats:p>\n          Material and methods Embryo recovery was carried out on days 8\u201310\n                    post-ovulation using transcervical uterine flushing. Recipient mares grouped\n                    according to their age were treated once on the day of embryo transfer (Day\n                    3\u20138 post ovulation) and were assigned randomly to 1 of 3 groups: Mares\n                    in Group A (n=101) received antispasmodic, antimicrobial, and\n                    anti-inflammatory drugs. Mares in Group B (n=100) received gentamicin\n                    and flunixin meglumine. Group C (control) (n=103) did not receive any\n                    treatment. Detomidine (0.008\u2009mg\/kg bwt i.v.) was administered to\n                    all recipients before transfer of the embryo. The influence of treatment and\n                    recipient\u00b4s age was calculated using binary logistic regression.<\/jats:p><jats:p>\n          Results Day 16 post-transfer pregnancy rates were highest in Group A\n                    (74\/101, 73.3a%), when compared to Group B\n                    (60\/100, 60%), and Group C (57\/103,\n                    55.3b%) (a vs b, p&lt;0.05). Pregnancy loss rates at D45\n                    were not different between groups, A (8\/74, 10.8%), B\n                    (5\/60, 8.3%), and C (6\/57, 10.5%), respectively\n                    (p&gt;0.05). Pregnancy losses were increased in recipient mares\n                    17\u201322 years (33.3a%) compared to younger recipient\n                    mares (2\u20136 years 7b%, 7\u201311 years 10%,\n                    12\u201316 years 8b%) (a:b p&lt;0.05). The regression\n                    model showed that the predicted probability for pregnancy after embryo transfer\n                    decreased as the age of the recipient mare increased for treated recipients in\n                    Group A (p=0.012), there was no effect of treatment and\n                    recipient\u00b4s age in Group B, and a decreased likelihood of pregnancy in\n                    recipients of advanced age (\u226512 years of age) in untreated recipients\n                    (group C).<\/jats:p><jats:p>\n          Conclusions and clinical relevance Likelihood of pregnancy increased\n                    following single administration of antispasmodic, antimicrobial, and\n                    anti-inflammatory drugs at the time of embryo transfer in recipients\n                    2\u201312 years of age. Likelihood of pregnancy in recipients decreased in\n                    recipients\u226512 years of age. These results, obtained under the conditions\n                    of a large commercial embryo transfer program, offer an opportunity to improve\n                    pregnancy rates in recipient mares\u226412 years of age.<\/jats:p>","DOI":"10.1055\/a-2186-2693","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T23:35:11Z","timestamp":1701905711000},"page":"358-366","source":"Crossref","is-referenced-by-count":1,"title":["Age and treatment on the day of embryo transfer in recipient mares\n                    affect likelihood of pregnancy"],"prefix":"10.1055","volume":"51","author":[{"given":"Miguel","family":"Blanco","sequence":"additional","affiliation":[{"name":"Studfarm Lewitz \u2013 PS Pferdehaltung, Neustadt-Glewe,\n                    Germany"},{"name":"Unit for Reproductive Medicine \u2013 Clinic for Horses, University\n                    of Veterinary Medicine Hanover, Foundation, Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Foss","sequence":"additional","affiliation":[{"name":"Equine Medical Services, Columbia, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"T\u00f6ni\u00dfen","sequence":"additional","affiliation":[{"name":"Unit for Reproductive Medicine \u2013 Clinic for Horses, University\n                    of Veterinary Medicine Hanover, Foundation, Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Rohn","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Epidemiology, University of Veterinary\n                    Medicine Hanover, Foundation, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Burger","sequence":"additional","affiliation":[{"name":"Swiss Institute of Equine Medicine ISME, University of Berne, and\n                    Agroscope, Avenches, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Sieme","sequence":"additional","affiliation":[{"name":"Unit for Reproductive Medicine \u2013 Clinic for Horses, University\n                    of Veterinary Medicine Hanover, Foundation, Hanover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,12,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1530\/jrf.0.0310187","article-title":"Non-surgical recovery of equine eggs, and an attempt at non-surgical egg\n                    transfer in horses","volume":"31","author":"N Oguri","year":"1972","journal-title":"J Reprod Fertil"},{"key":"ref2","first-page":"484","article-title":"Transfer of ova between horses and donkeys","volume":"7","author":"W R Allen","year":"1972","journal-title":"Proc Am Ass Equine 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Nutztiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2186-2693.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T23:35:50Z","timestamp":1701905750000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2186-2693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":28,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2023,12,6]]},"published-print":{"date-parts":[[2023,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2186-2693","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1434-1220","2567-5834"],"issn-type":[{"value":"1434-1220","type":"print"},{"value":"2567-5834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]}}}