{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T11:10:01Z","timestamp":1730805001631,"version":"3.28.0"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die bemannte Raumfahrt stellt besondere Anforderungen an den menschlichen K\u00f6rper, auch an die Organe im HNO-Bereich. Diese Organe spielen eine entscheidende Rolle bei der Aufrechterhaltung der Gesundheit und Sicherheit der Astronauten im Weltraum. In diesem Beitrag werden h\u00e4ufige HNO-Probleme in der Raumfahrt besprochen, darunter \u00d6deme der oberen Atemwege, Mittelohr- und Mastoiderg\u00fcsse, H\u00f6rverlust und Schwindel mit \u00dcbelkeit. Wir er\u00f6rtern die zugrunde liegenden Mechanismen, die zu diesen Beschwerden beitragen, ihre klinischen Erscheinungsformen und m\u00f6gliche Behandlungsstrategien. Dar\u00fcber hinaus untersuchen wir die m\u00f6glichen Auswirkungen dieser Erkrankungen auf die Gesundheit der Astronauten und die Ergebnisse der Mission. Schlie\u00dflich betonen wir die Bedeutung von Pr\u00e4ventivma\u00dfnahmen und zuk\u00fcnftiger Forschung in diesem Bereich, um die Gesundheit und Sicherheit der Astronauten auf zuk\u00fcnftigen Missionen zu optimieren.<\/jats:p>","DOI":"10.1055\/a-2192-7502","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T23:34:07Z","timestamp":1703288047000},"page":"275-278","source":"Crossref","is-referenced-by-count":0,"title":["Hals, Nase und Ohren in der Schwerelosigkeit: die kosmischen Herausforderungen der HNO-Heilkunde"],"prefix":"10.1055","volume":"103","author":[{"given":"Philipp Heinrich","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde und Kopf-Hals-Chirurgie, Universit\u00e4tsklinik K\u00f6ln,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Jansen","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde und Kopf-Hals-Chirurgie, Universit\u00e4tsklinik K\u00f6ln,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens Peter","family":"Klu\u00dfmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde und Kopf-Hals-Chirurgie, Universit\u00e4tsklinik K\u00f6ln,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2469","DOI":"10.1152\/jappl.1991.71.6.2469","article-title":"Transcapillary fluid shifts in tissues of the head and neck during and after simulated microgravity","volume":"71","author":"SE Parazynski","year":"1991","journal-title":"J Appl Physiol (1985)"},{"issue":"S 01","key":"ref2","doi-asserted-by":"publisher","first-page":"i143","DOI":"10.1093\/bja\/aex336","article-title":"An overview of space medicine","volume":"119","author":"PD Hodkinson","year":"2017","journal-title":"Br J Anaesth"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/978-0-387-68164-1_2","volume-title":"Human Response to Space Flight","author":"ES Baker","year":"2008"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e1915011","DOI":"10.1001\/jamanetworkopen.2019.15011","article-title":"Assessment of Jugular Venous Blood Flow Stasis and Thrombosis During Spaceflight","volume":"2","author":"K Marshall-Goebel","year":"2019","journal-title":"JAMA Netw Open"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1001\/jamaoto.2020.0228","article-title":"Spaceflight-Associated Changes in the Opacification of the Paranasal Sinuses and Mastoid Air Cells in Astronauts","volume":"146","author":"DC Inglesby","year":"2020","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1038\/s41526-019-0075-2","article-title":"Supplying a pharmacy for NASA exploration spaceflight: challenges and current understanding","volume":"5","author":"RS Blue","year":"2019","journal-title":"NPJ Microgravity"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e181","DOI":"10.1016\/j.amjmed.2020.09.020","article-title":"Gravity and Mastoid Effusion","volume":"134","author":"L Lecheler","year":"2021","journal-title":"Am J Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"350","DOI":"10.4187\/respcare.05172","article-title":"Radiographic Mastoid and Middle Ear Effusions in Intensive Care Unit Subjects","volume":"62","author":"P Huyett","year":"2017","journal-title":"Respir Care"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1001\/jamaoto.2020.0274","article-title":"Sinus Space in Outer Space","volume":"146","author":"MB Stenger","year":"2020","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s00405-016-4198-8","article-title":"Eustachian tube evaluation in aviators","volume":"274","author":"G Iannella","year":"2017","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"16063","DOI":"10.1038\/nrdp.2016.63","article-title":"Otitis media","volume":"2","author":"AGM Schilder","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1007\/s00106-013-2791-3","article-title":"Aerosinusitis: part 1: Fundamentals, pathophysiology and prophylaxis","volume":"62","author":"R Weber","year":"2014","journal-title":"HNO"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1007\/s00106-013-2828-7","article-title":"Aerosinusitis. 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