{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:51:47Z","timestamp":1788821507981,"version":"build-2803163510"},"reference-count":41,"publisher":"Georg Thieme Verlag KG","issue":"CP","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sports Med Int Open"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose EXERT-BC is a dose-escalated resistance training regimen created to\n                    improve body composition, strength, and balance in women treated for breast\n                    cancer (BC). Herein, we report the interim analysis. Women treated for BC\n                    underwent this 3-month exercise regimen in an exercise oncology facility with\n                    continual monitoring of load and strength. Twenty women completed the\n                    IRB-approved protocol, with a mean age of 57 years (range 41\u201374).\n                    Concurrent therapies included anti-estrogen therapy (73%), chemotherapy\n                    (14%), and radiotherapy (23%). 27% of women endorsed\n                    prior exercise. Subjects missed an average of 1.75 classes (range 0\u20137),\n                    with all meeting adherence over 75%. No injuries or adverse events were\n                    reported aside from muscle soreness and 2 days of knee pain. Significant\n                    differences in body composition at completion included reduced body fat\n                    (38.2% vs. 36.7%, p=0.003), and increased muscle mass\n                    (33.1% vs. 37.1%, p&lt;0.001), functional mobility\n                    screening (9.82 vs. 11.73, p=0.018), and Y-balance (left: 72.4 vs. 85.3,\n                    p=0.001; right: 70.3 vs. 85.2. p&lt;0.001). Significant increases\n                    in load were demonstrated: split squat (p&lt;0.001), trap bar deadlift\n                    (p=0.035), inclined dumbbell press (p&lt;0.001), and bird dog rows\n                    (p&lt;0.001). Dose-escalated resistance training in women with BC is safe\n                    and feasible, endorsing significant improvements across body composition,\n                    balance, and strength.<\/jats:p>","DOI":"10.1055\/a-2193-0922","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T23:12:39Z","timestamp":1697584359000},"source":"Crossref","is-referenced-by-count":6,"special_numbering":"S","title":["EXERT-BC: Prospective Study of an Exercise Regimen After Treatment\n                    for Breast Cancer"],"prefix":"10.1055","volume":"08","clinical-trial-number":[{"clinical-trial-number":"nct05747209","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1879-7463","authenticated-orcid":false,"given":"Colin E.","family":"Champ","sequence":"additional","affiliation":[{"name":"Exercise Oncology and Resiliency Center, Allegheny Health Network,\n                    Pittsburgh, United States"},{"name":"Department of Radiation Oncology, Allegheny Health Network, Pittsburgh,\n                    United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Peluso","sequence":"additional","affiliation":[{"name":"Exercise Oncology and Resiliency Center, Allegheny Health Network,\n                    Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Carenter","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Duke University Medical Center, Durham, United\n                    States"},{"name":"Department of Radiation Oncology, Wellstar Paulding Medical Center,\n                    Hiram, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Exercise Science, Syracuse University, Syracuse, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Velasquez","sequence":"additional","affiliation":[{"name":"Exercise Oncology and Resiliency Center, Allegheny Health Network,\n                    Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Annichine","sequence":"additional","affiliation":[{"name":"Exercise Oncology and Resiliency Center, Allegheny Health Network,\n                    Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krista","family":"Matsko","sequence":"additional","affiliation":[{"name":"Exercise Oncology and Resiliency Center, Allegheny Health Network,\n                    Pittsburgh, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parker N.","family":"Hyde","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of North Georgia, Dahlonega,\n                    United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander K.","family":"Diaz","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Duke University Medical Center, Durham, United\n                    States"},{"name":"Department of Radiation Oncology, Murray-Calloway County Hospital,\n                    Murray, KY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushil","family":"Beriwal","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Allegheny Health Network, Pittsburgh,\n                    United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christie","family":"Hilton","sequence":"additional","affiliation":[{"name":"Medical Oncology, Allegheny Health Network, Pittsburgh, United\n                    States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1038\/nrc1408","article-title":"Overweight, obesity and cancer: epidemiological evidence and proposed\n                    mechanisms","volume":"4","author":"E E Calle","year":"2004","journal-title":"Nat Rev Cancer"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1155\/2012\/506868","article-title":"Weight gain, metabolic syndrome, and breast cancer recurrence: Are dietary\n                    recommendations supported by the data?","volume":"2012","author":"C E Champ","year":"2012","journal-title":"Int J Breast Cancer"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12885-015-1971-9","article-title":"Physical activity before and after breast cancer diagnosis and survival\n                    \u2013 the Norwegian women and 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objective?","volume":"35","author":"J Rosenberg","year":"2021","journal-title":"J Strength Cond Res"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1080\/02640414.2016.1210197","article-title":"Dose-response relationship between weekly resistance training volume and\n                    increases in muscle mass: A systematic review and meta-analysis","volume":"35","author":"B J Schoenfeld","year":"2017","journal-title":"J Sports Sci"}],"container-title":["Sports Medicine International 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