{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T18:20:44Z","timestamp":1774894844028,"version":"3.50.1"},"reference-count":47,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>\n            Background\u2002Splenic lesions are rare and mostly incidental findings on cross-sectional imaging. Most lesions are of benign nature and can be correctly identified based on imaging characteristics. Further, invasive evaluation is only necessary in cases of splenic lesions with uncertain or potentially malignant etiology.<\/jats:p><jats:p>\n            Method\u2002While in most cases a correct diagnosis can be made from computed tomography (CT), (additional) magnetic resonance imaging (MRI) can aid in the identification of lesions. As these lesions are rare, only a few of the differential diagnoses are regularly diagnosed in the clinical routine.<\/jats:p><jats:p>\n            Result and Conclusion\u2002This review presents the differential diagnoses of splenic lesions, including imaging characteristics and a flowchart to determine the right diagnosis. In conjunction with laboratory results and clinical symptoms, histological workup is necessary only in a few cases, especially in incidental findings. In these cases, image-guided biopsies should be preferred over splenectomy, if possible.<\/jats:p><jats:p>\n            Key Points\u2002<\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-2193-2292","type":"journal-article","created":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T00:15:45Z","timestamp":1700093745000},"page":"573-581","source":"Crossref","is-referenced-by-count":9,"title":["Diagnostic approach to splenic lesions"],"prefix":"10.1055","volume":"196","author":[{"given":"Hermann","family":"Kr\u00e4hling","sequence":"additional","affiliation":[{"name":"Clinic of Radiology, University of M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Seidensticker","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter L.","family":"Heindel","sequence":"additional","affiliation":[{"name":"Clinic of Radiology, University of M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjam","family":"Gerwing","sequence":"additional","affiliation":[{"name":"Clinic of Radiology, University of M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/s40477-013-0014-0","article-title":"Focal splenic lesions: US findings","volume":"16","author":"M Caremani","year":"2013","journal-title":"J Ultrasound"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s00261-015-0605-7","article-title":"Prevalence of benign focal liver lesions: ultrasound investigation of 45,319 hospital patients","volume":"41","author":"T E 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