{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T04:37:08Z","timestamp":1792125428762,"version":"4.4.0"},"reference-count":36,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The present study employed a randomized crossover design to investigate the\n                    effect of strength-training exercise at varying intensities on acute changes in\n                    plasma brain-derived neurotrophic factor (BDNF) levels. Fourteen trained male\n                    subjects (41.0\u00b15.8 years old) were enrolled in the current study. The\n                    strength-training protocol included bench press, leg press, and lat pull-down\n                    exercises. Participants performed four sets with repetition failure at\n                    60% or 80% of their one-repetition maximum (1RM), with a\n                    two-minute rest period. The order of intensity was randomized among volunteers.\n                    Blood samples were collected before, immediately after, and one hour after each\n                    exercise protocol. A time-point comparison revealed that a single session of\n                    strength training at 60% of 1RM increased lactate plasma concentrations\n                    from 1.2 to 16\u2009mmol\/L (p&lt;0.0001). However, no\n                    significant changes were observed in the plasma BDNF concentration. Conversely,\n                    the training session at 80% of 1RM increased lactate concentrations from\n                    1.3 to 14\u2009mmol\/L (p&lt;0.0001) and BDNF concentrations from\n                    461 to 1730 pg\/ml (p=0.035) one hour after the session\u2019s\n                    conclusion. These findings support the hypothesis that a single\n                    strength-training session at 80% 1RM can significantly enhance\n                    circulating levels of BDNF.<\/jats:p>","DOI":"10.1055\/a-2197-1201","type":"journal-article","created":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T23:13:16Z","timestamp":1698102796000},"page":"155-161","source":"Crossref","is-referenced-by-count":10,"title":["Impact of Strength Training Intensity on Brain-derived Neurotrophic\n                    Factor"],"prefix":"10.1055","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7966-2709","authenticated-orcid":false,"given":"Marcos","family":"Borges Junior","sequence":"additional","affiliation":[{"name":"Neurosciense, UFMG, Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa Ferreira Jacomini","family":"Tavares","sequence":"additional","affiliation":[{"name":"Neurosciense, UFMG, Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Yumi","family":"Nagata","sequence":"additional","affiliation":[{"name":"Medicine School, UFMG, Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00e9lia Scarabeli Silva","family":"Barroso","sequence":"additional","affiliation":[{"name":"Pediatrics, Federal University of Minas Gerais, Belo Horizonte,\n                    Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heliana Barros","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Morphology, UFMG, Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Felipe","family":"Souza-Gomes","sequence":"additional","affiliation":[{"name":"Nutrition, UFOP, Ouro Preto, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Silva","family":"Miranda","sequence":"additional","affiliation":[{"name":"Morphology, UFMG, Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alben\u00e1","family":"Nunes-Silva","sequence":"additional","affiliation":[{"name":"Physical Education Department, UFOP, Ouro Preto, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3389\/fnagi.2022.965190","article-title":"The emerging neuroprotective roles of exerkines in Alzheimer\u2019s\n                    disease","volume":"14","author":"T Rody","year":"2022","journal-title":"Front Aging Neurosci"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/s12888-020-02583-3","article-title":"Physical exercise, mental health problems, and suicide attempts in university\n                    students","volume":"20","author":"M Grasdalsmoen","year":"2020","journal-title":"BMC 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