{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T05:27:48Z","timestamp":1730870868484,"version":"3.28.0"},"reference-count":7,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Anamnese\u2002Die 71-j\u00e4hrige Patientin berichtete von langj\u00e4hrig bestehenden entz\u00fcndlichen Arthralgien bei Psoriasis vulgaris. Eine Therapie mit Methotrexat hatte zu Leberwerterh\u00f6hungen gef\u00fchrt, unter Behandlung mit dem TNF\u03b1-Inhibitor Adalimumab persistierten die Beschwerden.<\/jats:p><jats:p>\n          Untersuchungen\u2002Mittels Arthrosonografie und MRT konnte ein vorwiegend periartikul\u00e4res Inflammationsmuster an Handgelenken, Metakarpophalangeal-Gelenken und proximalen Interphalangeal-Gelenken ohne postentz\u00fcndliche Stigmata einer Psoriasisarthritis objektiviert werden. Laborchemisch fand sich ein erh\u00f6hter anti-HCV-Titer mit hoher Viruslast im Sinne einer floriden Hepatitis C.<\/jats:p><jats:p>\n          Diagnose\u2002Eine vorwiegend extrahepatisch manifestierte Hepatitis C mit assoziierter Periarthritis wurde diagnostiziert.<\/jats:p><jats:p>\n          Therapie und Verlauf\u2002Unter kombinierter, interferonfreier antiviraler Therapie sistierten die Gelenkbeschwerden.<\/jats:p><jats:p>\n          Folgerung\u2002Die Hepatitis C kann sich durch extrahepatische Manifestationen im Sinne einer periartikul\u00e4ren Inflammation \u00e4u\u00dfern. Entz\u00fcndlich suspekte Arthralgien bei Psoriasis vulgaris sind nicht gleichbedeutend mit der Diagnose einer Psoriasisarthritis und sollten fachgerecht rheumatologisch evaluiert werden.<\/jats:p>","DOI":"10.1055\/a-2199-1549","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T23:30:27Z","timestamp":1706052627000},"page":"102-105","source":"Crossref","is-referenced-by-count":0,"title":["Arthralgien bei Psoriasis vulgaris \u2013 manchmal lohnt ein zweiter Blick"],"prefix":"10.1055","volume":"149","author":[{"given":"Philipp","family":"Schulte-Terhusen","sequence":"additional","affiliation":[{"name":"Rheumazentrum Ruhrgebiet Herne, St. Elisabeth Gruppe GmbH, Herne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xenofon","family":"Baraliakos","sequence":"additional","affiliation":[{"name":"Rheumazentrum Ruhrgebiet Herne, St. Elisabeth Gruppe GmbH, Herne"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitra","family":"Karagkiozidou","sequence":"additional","affiliation":[{"name":"Rheumazentrum Ruhrgebiet Herne, St. Elisabeth Gruppe GmbH, Herne"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1007\/s00296-023-05284-8","article-title":"Imaging methods in polymyalgia rheumatica: a systematic review","volume":"43","author":"L Mekenyan","year":"2023","journal-title":"Rheumatol Int"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00005792-200001000-00005","article-title":"Extrahepatic manifestations associated with hepatitis C virus infection. 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