{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:05:46Z","timestamp":1761897946197,"version":"3.30.2"},"reference-count":124,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Hyperemesis gravidarum (HG) ist eine multifaktorielle Erkrankung,\n                    charakterisiert durch persistierende \u00dcbelkeit\/Erbrechen,\n                    Dehydratation, Gewichtsverlust von mindestens 5%,\n                    Elektrolytst\u00f6rungen und Ketoazidose. Die Pr\u00e4valenz liegt\n                    weltweit zwischen 0,3 und 10%. Die Diagnose wird anhand der Anamnese,\n                    der klinischen Symptome, der k\u00f6rperlichen Untersuchung und der typischen\n                    Laborver\u00e4nderungen gestellt. Grundpfeiler der Therapie sind\n                    Ern\u00e4hrungsberatung, Beratung zum Lebensstil,\n                    psychologische\/psychosoziale Unterst\u00fctzung der Schwangeren und\n                    die Gabe von Antiemetika im Sinne eines sich an dem Schweregrad der Symptome\n                    orientierenden Stufenkonzepts. Ein h\u00e4ufiger Wechsel von Antiemetika ist\n                    zu vermeiden. Die Behandlung der HG erfordert eine enge interprofessionelle und\n                    interdisziplin\u00e4re Zusammenarbeit.<\/jats:p>","DOI":"10.1055\/a-2200-9686","type":"journal-article","created":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T00:45:16Z","timestamp":1702082716000},"page":"218-231","source":"Crossref","is-referenced-by-count":1,"title":["Hyperemesis gravidarum \u2013 eine interprofessionelle und\n                interdisziplin\u00e4re Herausforderung"],"prefix":"10.1055","volume":"228","author":[{"given":"Werner","family":"Rath","sequence":"additional","affiliation":[{"name":"Gyn\u00e4kologie und Geburtshilfe, Universit\u00e4tsklinikum\n                    Schleswig-Holstein, Campus Kiel, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Maul","sequence":"additional","affiliation":[{"name":"Geburtshilfe und Pr\u00e4natalmedizin, Asklepios Kliniken Hamburg,\n                    Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald","family":"Abele","sequence":"additional","affiliation":[{"name":"Frauenklinik, Universit\u00e4tklinikum T\u00fcbingen,\n                    T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Pauluschke","sequence":"additional","affiliation":[{"name":"Frauenklinik, Universit\u00e4tklinikum T\u00fcbingen,\n                    T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.gtc.2011.03.009","article-title":"Nausea and vomiting","volume":"40","author":"N M Lee","year":"2011","journal-title":"Gastroenterol Clin North Am"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0002-9378(00)70349-8","article-title":"Nausea and vomiting during pregnancy: a 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