{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:31:34Z","timestamp":1788258694494,"version":"build-2803163510"},"reference-count":40,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Erfassung der Health related quality of life (HRQL) hat in den letzten Jahren enorm an Bedeutung gewonnen. F\u00fcr die respiratorische Insuffizienz stehen krankheitsspezifische Frageb\u00f6gen zur Verf\u00fcgung, die die Erhebung der gesundheitsbezogenen Lebensqualit\u00e4t erm\u00f6glichen. Der \u201eSevere Respiratory Insufficiency\u201c (SRI)-Fragebogen, der speziell f\u00fcr Patient*innen mit respiratorischer Insuffizienz entwickelt wurde, eignet sich hervorragend zur Quantifizierung der Lebensqualit\u00e4t bei Patient*innen mit COPD und au\u00dferklinischer Beatmung. Basierend auf Untersuchungen mit dem SRI-Fragebogen ergab sich, dass die k\u00f6rperliche Funktionsf\u00e4higkeit bei Patient*innen mit chronischen Lungenerkrankungen unterschiedlicher Genese deutlich eingeschr\u00e4nkt ist, nicht selten jedoch ohne nennenswerte Einschr\u00e4nkungen des Wohlbefindens bleibt. Auch m\u00fcssen Erkrankungsschwere und Lebensqualit\u00e4t nicht in Korrelation zueinander stehen.<\/jats:p><jats:p>Sowohl invasive als auch nichtinvasive Beatmung k\u00f6nnen zur Verbesserung der Lebensqualit\u00e4t f\u00fchren. Hierbei m\u00fcssen Erkrankungsschwere und Lebensqualit\u00e4t nicht miteinander korrelieren.<\/jats:p><jats:p>Komorbidit\u00e4t und v.a. fortgeschrittenes Alter haben den h\u00f6chsten negativen pr\u00e4diktiven Wert bzgl. Krankenhausmortalit\u00e4t und Weaning-Versagen und der Anteil der \u00e4lter als 80-j\u00e4hrigen Patient*innen mit bleibender Abh\u00e4ngigkeit von au\u00dferklinischer invasiver Beatmung nach erfolglosem prolongiertem Weaning nimmt inzwischen deutlich zu. Hohe Abh\u00e4ngigkeit von invasiver au\u00dferklinischer Beatmung geht h\u00e4ufig mit Einbu\u00dfe der Lebensqualit\u00e4t und Autonomie einher. Vor diesem Hintergrund werden ethische Aspekte von beatmeten Patient*innen am Lebensende zunehmend thematisiert.<\/jats:p><jats:p>Nach erfolgloser Respiratorentw\u00f6hnung sollte die Indikation zur au\u00dferklinischen Beatmung angesichts der oft stark reduzierten Lebensqualit\u00e4t und schlechter Prognose sowie unter Ber\u00fccksichtigung des Willens der Patient*innen kritisch gepr\u00fcft werden.<\/jats:p><jats:p>Sind im Verlauf einer invasiven au\u00dferklinischen Beatmung die zuvor konsentierten Therapieziele nicht mehr erreichbar, sollten Gespr\u00e4che zur Therapieziel\u00e4nderung im Behandlungsteam, mit den Patient*innen, deren Angeh\u00f6rigen und ggf. mit gesetzlichen Vertreter*innen (z.B. auch in Form einer Fall- oder Familienkonferenz) gef\u00fchrt werden.<\/jats:p><jats:p>Um \u00dcbertherapie und unn\u00f6tiges Leiden von Patient*innen in der invasiven au\u00dferklinischen Beatmung zu vermeiden, sollten eine vorausschauende Versorgungsplanung (\u201eAdvanced Care Planning\u201c) m\u00f6glichst fr\u00fchzeitig beginnen und ggf. durch palliativmedizinische Ma\u00dfnahmen begleitet werden.<\/jats:p>","DOI":"10.1055\/a-2202-5558","type":"journal-article","created":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T23:51:10Z","timestamp":1704930670000},"page":"409-416","source":"Crossref","is-referenced-by-count":5,"title":["Au\u00dferklinische Beatmung: Lebensqualit\u00e4t und Lebensende"],"prefix":"10.1055","volume":"78","author":[{"given":"Sarah Bettina","family":"Stanzel","sequence":"additional","affiliation":[{"name":"Lungenklinik, Kliniken der Stadt K\u00f6ln gGmbH, Universit\u00e4t Witten\/Herdecke, K\u00f6ln, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Sch\u00f6nhofer","sequence":"additional","affiliation":[{"name":"Pneumologie und Intensivmedizin, Universit\u00e4tsklinik Ostwestfalen-Lippe (OWL), Evangelisches Klinikum Bethel (EvKB), Bielefeld, Deutschland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,1,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF00435734","article-title":"Study protocol for the World Health Organization project to develop a Quality of Life assessment instrument (WHOQOL)","volume":"2","author":"WHOQOL Group","year":"1993","journal-title":"Quality of Life Research"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1055\/s-0029-1239516","article-title":"Die Erfassung von Lebensqualit\u00e4t in der Versorgungsforschung \u2013 konzeptuelle, methodische und strukturelle Voraussetzungen","volume":"71","author":"M Koller","year":"2009","journal-title":"Gesundheitswesen"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1055\/s-2006-932152","article-title":"Lebensqualit\u00e4t bei Patienten mit h\u00e4uslicher Beatmung","volume":"60","author":"WC Windisch","year":"2006","journal-title":"Pneumologie"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/s0895-4356(98)00081-x","article-title":"Overview of the SF-36 health survey and the international quality of life\n          assessment (IQOLA) project","volume":"51","author":"JE Ware Jr","year":"1998","journal-title":"J Clin Epidemiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36): I. 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