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Die Einf\u00fchrung des Procalcitonins (PCT) im Serum als zus\u00e4tzlichen Biomarker zur Unterscheidung zwischen bakterieller und viraler Meningitis.<\/jats:p><jats:p>\n            Mikrobiologische Diagnostik: Die Verwendung der Multiplex-PCR \u2013 als Erg\u00e4nzung, nicht als Ersatz der Standarddiagnostik \u2013 zur Beschleunigung der Erregeridentifikation.<\/jats:p><jats:p>\n            Antiinfektiva-Therapie: Anpassung der Antibiotika-Empfehlungen, basierend auf der aktuellen Resistenzlage; insbesondere bei Meningokokken-Meningitis die Ber\u00fccksichtigung von Penicillin G nur nach Resistenztestung.<\/jats:p><jats:p>\n            Dexamethason: Einsatzgebiete und -dauer der Dexamethason-Gabe bei bakterieller Meningitis, insbesondere solide Datenlage bei Pneumokokken-Meningitis, und kontroversen Datenlage bei Listerien-Meningitis.<\/jats:p><jats:p>\n            Intrakranielle Komplikationen: Neue Erkenntnisse zur sicheren Anwendung von Heparin bei septischen Sinusthrombosen ohne 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