{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T17:10:07Z","timestamp":1730826607983,"version":"3.28.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n            Einleitung Die Adenotomie (AT) stellt eine der ersten und h\u00e4ufigsten Operationen im Kindesalter dar. M\u00f6gliche Gerinnungsst\u00f6rungen (GS) sind zum OP-Zeitpunkt h\u00e4ufig noch nicht diagnostiziert. Im Jahr 2006 empfahlen die Deutschen Gesellschaften f\u00fcr An\u00e4sthesiologie &amp; Intensivmedizin sowie Kinder- &amp; Jugendmedizin und HNO-Heilkunde, Kopf- und Hals-Chirurgie, im Rahmen der pr\u00e4operativen Vorbereitungen f\u00fcr eine AT auf die routinem\u00e4\u00dfige Blutentnahme zu verzichten und stattdessen einen standardisierten Gerinnungsbogen (GB) zur Abkl\u00e4rung einer GS zu verwenden. Wenn hingegen Auff\u00e4lligkeiten bestehen, ist die Indikation zur Gerinnungsdiagnostik (GD) indiziert.<\/jats:p><jats:p>\n            Material und Methoden In dieser unizentrischen, nicht randomisierten, retrospektiven Studie erhielten zwischen dem 01.01.2011 und dem 31.12.2018 insgesamt 2633 Kinder zwischen dem 1. und dem 6. Lebensjahr eine AT oder Re-AT, die in die weiteren Analysen eingeschlossen wurden. Es sollte eruiert werden, ob durch die Einf\u00fchrung des GB im Jahr 2014 die Nachblutungsrate nach AT gesenkt werden konnte.<\/jats:p><jats:p>\n            Ergebnisse Von den 2633 Kindern hatten 1451 einen GB und 1182 keinen GB. Es ergab sich eine Nachblutungsrate von 0,83% ohne GB und von 2,08% mit GB. 174 GB waren auff\u00e4llig, und es erfolgten 169 GD, 164 hiervon waren unauff\u00e4llig, 2 ergaben ein gesichertes mildes Typ-1-von-Willebrand-Syndrom (vWS) sowie 2 den V.a. ein vWS und eine den V.a. einen Faktor-VII-Mangel. Die Sensitivit\u00e4t des GB betrug 16% und die Spezifit\u00e4t 87,5%. Der positive pr\u00e4diktive Wert lag bei 2,8% und der negative pr\u00e4diktive Wert bei 98%.<\/jats:p><jats:p>\n            Schlussfolgerungen Ergebnis dieser Untersuchungen war, dass der GB ein Werkzeug daf\u00fcr ist, eine m\u00f6gliche GS zu detektieren, jedoch nicht daf\u00fcr geeignet ist, die Nachblutungsrate zu senken.<\/jats:p>","DOI":"10.1055\/a-2209-6169","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T23:34:07Z","timestamp":1703288047000},"page":"358-364","source":"Crossref","is-referenced-by-count":0,"title":["Ver\u00e4ndert die Einf\u00fchrung eines pr\u00e4operativen Gerinnungsbogens die Nachblutungsrate nach Adenotomie?"],"prefix":"10.1055","volume":"103","author":[{"given":"Georges","family":"Joseph","sequence":"additional","affiliation":[{"name":"HNO \/ Kopf & Halschirurgie, Klinikum Mutterhaus der Borrom\u00e4erinnen gGmbH, Trier, 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