{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:51Z","timestamp":1740126831170,"version":"3.37.3"},"reference-count":68,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Congenital LQTS is an often undetected inherited cardiac channel dysfunction and\n                    can be a reason for intrauterine fetal demise. It can present in utero as CTG\n                    and ultrasound abnormalities, i.\u2009e., bradycardia, ventricular tachycardia, or\n                    fetal hydrops. Diagnosis is made by CTG, echocardiography, or fMCG. Intrauterine\n                    therapy with a \u00df blocker and i.\u2009v. magnesium should be started. Our objective\n                    was to examine the current knowledge about diagnosis and treatment of LQTS and\n                    in particular to highlight the opportunity of vaginal birth under continuous\n                    intravenous magnesium therapy. Therefore, a thorough MEDLINE and Google Scholar\n                    search was conducted. Randomized controlled trials, meta-analyses, prospective\n                    and retrospective cohort trials, and case reports were considered. We showed the\n                    possibility of vaginal delivery under continuous magnesium therapy in a case of\n                    suspected fetal LQTS. A stepwise concept for diagnosis, monitoring, and\n                    peripartum management in low, intermediate, and high risk cases of fetal LQTS is\n                    presented. If risk is low or intermediate, a vaginal delivery under continuous\n                    monitoring is reasonable. Induction of labor at term should be evaluated.<\/jats:p>","DOI":"10.1055\/a-2231-9348","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T00:07:20Z","timestamp":1708646840000},"page":"328-339","source":"Crossref","is-referenced-by-count":0,"title":["Fetal Long QT Syndrome \u2013 Challenges in Perinatal Management: A Review\n                    and Case Report. Induction of Labor and Vaginal Birth Under Continuous Magnesium\n                    Therapy"],"prefix":"10.1055","volume":"228","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5216-1290","authenticated-orcid":false,"given":"Linda Sarah","family":"Wegner","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, St. Franziskus-Hospital M\u00fcnster GmbH,\n                    M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Steinhard","sequence":"additional","affiliation":[{"name":"Department of Fetal Cardiology, Heart and Diabetes Center, Bad\n                    Oeynhausen Hospital, Bad Oeynhausen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Neonatology and Pediatric Intensive Care, St.\n                    Franziskus-Hospital M\u00fcnster GmbH, M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai Thorsten","family":"Laser","sequence":"additional","affiliation":[{"name":"Department of Fetal Cardiology, Heart and Diabetes Center, Bad\n                    Oeynhausen Hospital, Bad Oeynhausen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karol","family":"Kubiak","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, St. Franziskus-Hospital M\u00fcnster GmbH,\n                    M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1161\/CIRCULATIONAHA.109.863209","article-title":"Prevalence of the congenital long-QT syndrome","volume":"120","author":"P J 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Tanaka","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1111\/jch.13397","article-title":"Beta-blocker subtypes and risk of low birth weight in newborns","volume":"20","author":"L Duan","year":"2018","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1159\/000443880","article-title":"Update reference charts: fetal biometry between the 15th and 20th week of\n                    gestation","volume":"40","author":"K Kubiak","year":"2016","journal-title":"Fetal Diagn Ther"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1161\/CIRCULATIONAHA.107.707877","article-title":"Gating properties of SCN5A mutations and the response to mexiletine in long-QT\n                    syndrome Type 3 patients","volume":"116","author":"Y 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Shima","year":"2020","journal-title":"J Cardiol Cases"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"186\u2013190","DOI":"10.1016\/j.ipej.2021.03.001","article-title":"Ventricular noncompaction and long QT syndrome \u2013 A deadly double hit for the\n                    foetus","volume":"21","author":"A G Cherian","year":"2021","journal-title":"Indian Pacing Electrophysiol J"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"64","DOI":"10.4103\/apc.apc_34_21","article-title":"Congenital long QT syndrome: A challenging diagnosis by fetal\n                    echocardiography","volume":"15","author":"A Santi","year":"2022","journal-title":"Ann Pediatr Cardiol"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/j.hrcr.2022.07.007","article-title":"Presentation and genetic confirmation of long QT syndrome in the fetus","volume":"8","author":"V Zidere","year":"2022","journal-title":"HeartRhythm Case Rep"}],"container-title":["Zeitschrift 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