{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T19:23:46Z","timestamp":1785266626883,"version":"3.55.0"},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The PRESERFLO\u2122 MicroShunt (MP; Santen Inc., Osaka, Japan) is a minimally invasive bleb surgery (MIBS) manufactured to treat primary open-angle glaucoma (POAG), with lower postoperative adverse effects than with conventional filtering surgeries. We describe here the case study of a 58-year-old woman who presented with bilateral severe myopia with bilateral advanced POAG and unreached target pressure under quadritherapy, who was successfully managed by PM surgery. A review of the literature completes our observation. At presentation, the patient had a spherical equivalent of \u2212\u20097.50 RE and \u2212\u20097.75 LE with an IOP of 22\u2009mmHg right and left eye (RLE) under quadritherapy, and with severe bilateral visual field loss, including scotomas within the central 5\u00b0. The patient presented with systemic hypertension treated with an antihypertensive drug. Two selective laser trabeculoplasties (SLT), performed 3 months apart, were first tried on the LE, without any change in IOP at 2\n          months. After considering the high risk of postoperative complications, a PM operation was proposed, with a targeted IOP in the mid-fifteens RLE. The patient\u02bcs eyes underwent PM surgery with mitomycin C (MMC) MMC0.2\u2009mg\/mL for 3 minutes without any complications. The LE required 2 consecutive needlings with 1\u2009mL MMC0.2\u2009mg\/mL. At 24 months after surgery, the two eyes gave successful results without the need for any additional medical therapy, and with well-functioning conjunctival blebs. The PM was an effective alternative to the gold standard trabeculectomy in our severely myopic patient. A comparative study between conventional filtering operations and this MIBS in highly myopic patients would confirm our observation.<\/jats:p>","DOI":"10.1055\/a-2239-0636","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T22:51:25Z","timestamp":1713912685000},"page":"361-366","source":"Crossref","is-referenced-by-count":1,"title":["PRESERFLO MicroShunt in Severe Myopia: A Case Report and Review of the Literature"],"prefix":"10.1055","volume":"241","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1942-0100","authenticated-orcid":false,"given":"J\u00e9r\u00f4me","family":"George","sequence":"additional","affiliation":[{"name":"Ophthalmology, University of Geneva, Faculty of Medicine, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Abouzeid","sequence":"additional","affiliation":[{"name":"Ophthalmology, University of Geneva, Faculty of Medicine, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,4,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1038\/s41433-021-01805-6","article-title":"Myopia prediction: a systematic review","volume":"36","author":"X Han","year":"2022","journal-title":"Eye (Lond)"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1167\/iovs.61.4.49","article-title":"The Complications of Myopia: A Review and Meta-Analysis","volume":"61","author":"A EG Haarman","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"e0175120","DOI":"10.1371\/journal.pone.0175120","article-title":"Glaucoma in high myopia and parapapillary delta zone","volume":"12","author":"J B Jonas","year":"2017","journal-title":"PLoS 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