{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:03:48Z","timestamp":1790240628865,"version":"4.1.0"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background Adenoma detection rate (ADR) is an important indicator of colonoscopy quality and colorectal cancer incidence. Both linked-color imaging (LCI) with artificial intelligence (LCA) and LCI alone increase adenoma detection during colonoscopy, although it remains unclear whether one modality is superior. This study compared ADR between LCA and LCI alone, including according to endoscopists\u2019 experience (experts and trainees) and polyp size.<\/jats:p>\n                  <jats:p>Methods Patients undergoing colonoscopy for positive fecal immunochemical tests, follow-up of colon polyps, and abdominal symptoms at a single institution were randomly assigned to the LCA or LCI group. ADR, adenoma per colonoscopy (APC), cecal intubation time, withdrawal time, number of adenomas per location, and adenoma size were compared.<\/jats:p>\n                  <jats:p>Results The LCA (n=400) and LCI (n=400) groups showed comparable cecal intubation and withdrawal times. The LCA group showed a significantly higher ADR (58.8% vs. 43.5%; P&lt;0.001) and mean (95%CI) APC (1.31 [1.15 to 1.47] vs. 0.94 [0.80 to 1.07]; P&lt;0.001), particularly in the ascending colon (0.30 [0.24 to 0.36] vs. 0.20 [0.15 to 0.25]; P=0.02). Total number of nonpolypoid-type adenomas was also significantly higher in the LCA group (0.15 [0.09 to 0.20] vs. 0.08 [0.05 to 0.10]; P=0.02). Small polyps (\u22645, 6\u20139mm) were detected significantly more frequently in the LCA group (0.75 [0.64 to 0.86] vs. 0.48 [0.40 to 0.57], P&lt;0.001 and 0.34 [0.26 to 0.41] vs. 0.24 [0.18 to 0.29], P=0.04, respectively). In both groups, ADR was not significantly different between experts and trainees.<\/jats:p>\n                  <jats:p>Conclusions LCA was significantly superior to LCI alone in terms of ADR.<\/jats:p>","DOI":"10.1055\/a-2239-8145","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T19:06:12Z","timestamp":1704740772000},"page":"376-383","source":"Crossref","is-referenced-by-count":27,"title":["Linked-color imaging with or without artificial intelligence for adenoma detection: a randomized trial"],"prefix":"10.1055","volume":"56","clinical-trial-number":[{"clinical-trial-number":"umin000046361","registry":"10.18810\/umin-japan"}],"author":[{"given":"Kazuya","family":"Miyaguchi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshikazu","family":"Tsuzuki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobutaka","family":"Hirooka","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Ohgo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetomo","family":"Nakamoto","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0898-6540","authenticated-orcid":false,"given":"Hiroyuki","family":"Imaeda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"H Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.gie.2014.07.058","article-title":"Quality indicators for colonoscopy","volume":"81","author":"DK Rex","year":"2015","journal-title":"Gastrointest 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Pohl","year":"2015","journal-title":"Endoscopy"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1055\/s-0043-117879","article-title":"Higher adenoma detection rate with the Endocuff: a randomized trial","volume":"49","author":"C Gonz\u00e1lez-Fern\u00e1ndez","year":"2017","journal-title":"Endoscopy"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1136\/gutjnl-2017-314889","article-title":"Improved adenoma detection with Endocuff Vision: the ADENOMA randomised controlled trial","volume":"68","author":"WS Ngu","year":"2019","journal-title":"Gut"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1055\/s-0034-1392421","article-title":"Multicenter, randomized, tandem evaluation of EndoRings colonoscopy \u2013 results of the CLEVER study","volume":"47","author":"VK Dik","year":"2015","journal-title":"Endoscopy"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1055\/a-1379-6868","article-title":"Adenoma detection by Endocuff-assisted versus standard colonoscopy in an organized screening program: the \u201cItaVision\u201d randomized controlled trial","volume":"54","author":"M Zorzi","year":"2022","journal-title":"Endoscopy"}],"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2239-8145.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T07:47:14Z","timestamp":1730792834000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2239-8145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,8]]},"references-count":34,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,4,23]]},"published-print":{"date-parts":[[2024,5]]}},"URL":"https:\/\/doi.org\/10.1055\/a-2239-8145","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1,8]]},"published":{"date-parts":[[2024,1,8]]}}}